askafex tr suspension - Terbutaline (2.5mg/5ml) + Bromhexine (8mg/5ml) medicine

askafex tr suspension - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Asklepios Remedies Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is askafex tr suspension used for?

Askafex TR Suspension (Terbutaline + Bromhexine) is used to treat RESPIRATORY. It contains Terbutaline (2.5mg/5ml) + Bromhexine (8mg/5ml), which Terbutaline stimulates beta-2 adrenergic receptors causing bronchodilation; Brom. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Terbutaline + Bromhexine
  • Manufacturer: Asklepios Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š askafex tr suspension Uses & Benefits

Bronchial asthma, chronic bronchitis, COPD with productive cough

Off-label uses: Not well established

๐Ÿ“‹ Drug Information

Generic Name(s)Terbutaline + Bromhexine
Brand NameAskafex TR Suspension
ManufacturerAsklepios Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassBronchodilator + Mucolytic
Route of AdministrationOral
StorageStore at room temperature (15-30ยฐC), protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from gastrointestinal tract
DistributionDistributes widely into body tissues and fluids
Protein BindingTerbutaline: ~20%; Bromhexine: ~90%
MetabolismTerbutaline: Hepatic via sulfation; Bromhexine: Hepatic via CYP450
Half-LifeTerbutaline: 3-4 hours; Bromhexine: 12 hours
ExcretionTerbutaline: Renal (60% unchanged); Bromhexine: Renal (metabolites)
BioavailabilityTerbutaline: ~15-20% (oral); Bromhexine: ~75-80%
Onset of ActionTerbutaline: 30 minutes; Bromhexine: 1 hour
Peak Plasma TimeTerbutaline: 2-3 hours; Bromhexine: 1-2 hours
Duration of ActionTerbutaline: 4-6 hours; Bromhexine: 8-12 hours

How It Works

Terbutaline stimulates beta-2 adrenergic receptors causing bronchodilation; Bromhexine reduces mucus viscosity by depolymerizing mucopolysaccharides

Mechanism Steps

1Terbutaline binds to beta-2 adrenergic receptors on bronchial smooth muscle
2Activates adenylate cyclase, increasing cAMP
3cAMP causes relaxation of bronchial smooth muscle

๐Ÿ’ก How to Take askafex tr suspension

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of askafex tr suspension

โœ… Common Side Effects

  • Tremor
  • Headache
  • Nausea
  • Dizziness
  • Cough

๐Ÿšจ Serious Side Effects

  • Tachycardia
  • Hypokalemia
  • Paradoxical bronchospasm
  • Cardiac arrhythmias

โš ๏ธ Rare Side Effects

  • Hypersensitivity reactions
  • Hepatotoxicity
  • Nephrotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Hypertensive crisis
Beta-blockers Major Antagonism of bronchodilator effect
Diuretics Major Hypokalemia
Corticosteroids Major Increased hypokalemia risk
Theophylline Moderate Increased cardiac toxicity
Anticholinergics Moderate Additive anticholinergic effects
Halogenated anesthetics Moderate Cardiac arrhythmias
Sympathomimetics Minor Additive sympathomimetic effects
Xanthine derivatives Minor Increased CNS stimulation

๐Ÿšจ Major Interactions

  • MAOIs
  • Beta-blockers
  • Diuretics
  • Corticosteroids

โšก Moderate Interactions

  • Theophylline
  • Anticholinergics
  • Halogenated anesthetics

โ„น๏ธ Minor Interactions

  • Sympathomimetics
  • Xanthine derivatives

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase sedation or hepatotoxicity risk

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, tachyarrhythmias, hypertrophic obstructive cardiomyopathy, severe hypertension

๐Ÿ“Š Monitoring Parameters

Heart rate, blood pressure, serum potassium, respiratory function

๐Ÿคฑ Lactation Safety

Caution; excreted in breast milk

๐Ÿ’Š Overdose Management

Gastric lavage, activated charcoal, supportive measures; beta-blockers for severe tachycardia

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

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