asizolam 0.25mg tablet - Etizolam (0.25mg) medicine

asizolam 0.25mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Shiron Pharmaceuticals ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is asizolam 0.25mg tablet used for?

Anxifit 50mg Tablet (Etizolam) is used to treat NEURO CNS. It contains Etizolam (0.25mg), which Enhances the inhibitory effects of gamma-aminobutyric acid (GABA) by binding to . Always consult your doctor before use. Take as prescribed.

  • Generic Name: Etizolam
  • Manufacturer: Shiron Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š asizolam 0.25mg tablet Uses & Benefits

Short-term management of anxiety disorders, panic attacks, and insomnia; adjunctive treatment for depression with anxiety.

Off-label uses: Restless legs syndrome, premenstrual dysphoric disorder, catatonia, and as a muscle relaxant.

๐Ÿ“‹ Drug Information

Generic Name(s)Etizolam
Brand NameAnxifit 50mg Tablet
ManufacturerShiron Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassBenzodiazepines
Route of AdministrationOral.
StorageStore at room temperature (20-25ยฐC) in a dry place, protected from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract with oral administration.
DistributionWidely distributed throughout the body; crosses the blood-brain barrier.
Protein BindingApproximately 93% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via CYP3A4 and CYP2C9 to active metabolites (alpha-hydroxyetizolam and 8-hydroxyetizolam).
Half-LifeApproximately 3.4 hours for parent drug; active metabolites have longer half-lives.
ExcretionPrimarily excreted in urine (90%) as metabolites, with less than 1% unchanged.
BioavailabilityApproximately 93% after oral administration.
Onset of ActionRapid onset within 15-30 minutes.
Peak Plasma TimePeak plasma concentrations reached in 0.5-2 hours.
Duration of ActionShort to intermediate duration of action (4-6 hours).

How It Works

Enhances the inhibitory effects of gamma-aminobutyric acid (GABA) by binding to benzodiazepine receptors on GABA-A receptors, increasing chloride ion channel opening frequency.

Mechanism Steps

1Binds to benzodiazepine site on GABA-A receptor
2Enhances GABA affinity for the receptor
3Increases frequency of chloride channel opening

๐Ÿ’ก How to Take asizolam 0.25mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of asizolam 0.25mg tablet

โœ… Common Side Effects

  • Drowsiness
  • Dizziness
  • Fatigue
  • Ataxia
  • Slurred speech
  • Headache
  • Blurred vision

๐Ÿšจ Serious Side Effects

  • Respiratory depression
  • Paradoxical reactions (agitation, aggression)
  • Physical dependence
  • Withdrawal seizures
  • Suicidal ideation

โš ๏ธ Rare Side Effects

  • Jaundice
  • Blood dyscrasias
  • Anaphylaxis
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Alcohol Major Enhanced sedation and respiratory depression
Opioids Major Increased risk of profound sedation, respiratory depression, coma, and death
Ketoconazole Major Increased etizolam plasma concentration due to CYP3A4 inhibition
Rifampin Major Decreased etizolam efficacy due to CYP3A4 induction
Antacids Moderate Reduced absorption of etizolam
Oral Contraceptives Moderate May increase etizolam half-life
Grapefruit Juice Minor May increase etizolam levels

๐Ÿšจ Major Interactions

  • CNS Depressants (e.g., alcohol, opioids, barbiturates)
  • CYP3A4 Inhibitors (e.g., ketoconazole, ritonavir)
  • CYP3A4 Inducers (e.g., rifampin, carbamazepine)

โšก Moderate Interactions

  • Antacids
  • Oral Contraceptives
  • Theophylline

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Disulfiram
  • Grapefruit Juice

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase plasma levels; high-fat meals may delay absorption.

๐Ÿท Alcohol Interaction

Additive CNS depression; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to etizolam or other benzodiazepines; severe respiratory insufficiency; myasthenia gravis; narrow-angle glaucoma; severe hepatic impairment; pregnancy (especially first trimester); breastfeeding.

๐Ÿ“Š Monitoring Parameters

Monitor for sedation, respiratory depression, dependence, and withdrawal symptoms; periodic liver function tests.

๐Ÿคฑ Lactation Safety

Not recommended; etizolam is excreted in breast milk and may cause sedation in the infant.

๐Ÿ’Š Overdose Management

Supportive care; gastric lavage if recent ingestion; administer flumazenil (benzodiazepine antagonist) with caution due to risk of seizures.

โฐ Missed Dose

If missed, take as soon as remembered unless close to next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for asizolam 0.25mg tablet

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Alternative brands with exact same active ingredient (Etizolam (0.25mg)):

Medical Note: Always consult your doctor before switching medications.

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