asevator 10mg tablet - Asenapine (10mg) medicine

asevator 10mg tablet - Uses, Price, Side Effects & Substitutes

No reviews yet
๐Ÿญ Ryon Pharma ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is asevator 10mg tablet used for?

Azin 10mg Tablet (Asenapine) is used to treat NEURO CNS. It contains Asenapine (10mg), which Antagonist at dopamine D2 and serotonin 5-HT2A receptors; also has affinity for . Always consult your doctor before use. Take as prescribed.

  • Generic Name: Asenapine
  • Manufacturer: Ryon Pharma
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š asevator 10mg tablet Uses & Benefits

Schizophrenia; acute treatment of manic or mixed episodes associated with bipolar I disorder.

Off-label uses: Treatment-resistant depression; Tourette syndrome; borderline personality disorder.

๐Ÿ“‹ Drug Information

Generic Name(s)Asenapine
Brand NameAzin 10mg Tablet
ManufacturerRyon Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassAtypical Antipsychotics
Route of AdministrationSublingual (tablet placed under tongue until dissolved).
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after sublingual administration; bioavailability is approximately 35% due to extensive first-pass metabolism.
DistributionVolume of distribution is approximately 20-25 L/kg; highly protein bound.
Protein Binding95% bound to plasma proteins, mainly albumin and alpha-1-acid glycoprotein.
MetabolismExtensively metabolized in the liver via glucuronidation (UGT1A4) and oxidative metabolism (CYP1A2); also metabolized by CYP3A4 and CYP2D6 to a lesser extent.
Half-LifeApproximately 24 hours.
ExcretionAbout 50% excreted in urine and 40% in feces, mostly as metabolites.
Bioavailability35% (sublingual); oral bioavailability is negligible due to first-pass metabolism.
Onset of ActionWithin 1-2 hours.
Peak Plasma Time0.5-1.5 hours after sublingual administration.
Duration of ActionApproximately 24 hours.

How It Works

Antagonist at dopamine D2 and serotonin 5-HT2A receptors; also has affinity for other receptors.

Mechanism Steps

1Asenapine binds to dopamine D2 receptors in the mesolimbic pathway, reducing positive symptoms of schizophrenia.
2Antagonism of serotonin 5-HT2A receptors in the frontal cortex improves negative symptoms and reduces extrapyramidal side effects.
3Blockade of 5-HT2C receptors may contribute to weight gain and metabolic effects.

๐Ÿ’ก How to Take asevator 10mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of asevator 10mg tablet

โœ… Common Side Effects

  • Somnolence
  • Dizziness
  • Extrapyramidal symptoms
  • Weight gain
  • Increased appetite
  • Dry mouth
  • Constipation
  • Dysgeusia

๐Ÿšจ Serious Side Effects

  • Neuroleptic malignant syndrome
  • Tardive dyskinesia
  • QT prolongation
  • Seizures
  • Hyperglycemia
  • Dyslipidemia

โš ๏ธ Rare Side Effects

  • Hepatic failure
  • Agranulocytosis
  • Pancreatitis
  • Priapism
  • Allergic reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Fluvoxamine Major Increased asenapine levels due to CYP1A2 inhibition
Carbamazepine Major Decreased asenapine levels due to CYP1A2 induction
Levodopa Major Antagonism of dopaminergic effects
Alcohol Moderate Increased CNS depression and sedation
Grapefruit juice Minor Possible increase in asenapine levels

๐Ÿšจ Major Interactions

  • CYP1A2 inhibitors (e.g., fluvoxamine)
  • CYP1A2 inducers (e.g., carbamazepine)
  • Dopamine agonists
  • Levodopa

โšก Moderate Interactions

  • Antihypertensives
  • CNS depressants (e.g., alcohol, benzodiazepines)
  • QTc-prolonging drugs

โ„น๏ธ Minor Interactions

  • CYP2D6 substrates
  • CYP3A4 substrates

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase asenapine levels; avoid high-fat meals within 10 minutes of administration.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase CNS depression and hypotensive effects.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to asenapine or any excipients; severe hepatic impairment.

๐Ÿ“Š Monitoring Parameters

Mental status, blood pressure, heart rate, ECG (QTc interval), liver function tests, blood glucose, lipid profile, weight.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk in animal studies.

๐Ÿ’Š Overdose Management

Supportive care; monitor vital signs, ECG, and mental status; no specific antidote.

โฐ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for asevator 10mg tablet

View All

Alternative brands with exact same active ingredient (Asenapine (10mg)):

Medical Note: Always consult your doctor before switching medications.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory
SaathiMed App
SaathiMed App Consult doctors & order medicines faster
Install