arthrin plus 100 mg/500 mg tablet - Uses, Price, Side Effects & Substitutes
What is arthrin plus 100 mg/500 mg tablet used for?
Aldigesic P (Aceclofenac + Paracetamol) is used to treat Pain and inflammation in osteoarthritis. It contains Aceclofenac (100mg) + Paracetamol (500mg), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paraceta. Always consult your doctor before use. Take as prescribed.
- Generic Name: Aceclofenac + Paracetamol
- Manufacturer: Elan Pharma India Pvt Ltd
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 arthrin plus 100 mg/500 mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
arthrin plus 100 mg/500 mg tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Aceclofenac (100mg) + Paracetamol (500mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Aceclofenac + Paracetamol |
|---|---|
| Brand Name | Aldigesic P |
| Manufacturer | Elan Pharma India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C), protect from moisture. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take arthrin plus 100 mg/500 mg tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at room temperature (20-25°C), protect from moisture.
⚙️ How arthrin plus 100 mg/500 mg tablet Works
Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.
💊 arthrin plus 100 mg/500 mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, dysmenorrhea, fever.
Off-label uses: Postoperative pain, migraine (limited evidence).
⚠️ What are the side effects of arthrin plus 100 mg/500 mg tablet?
✅ Common Side Effects
- Nausea
- Dizziness
- Drowsiness
- Rash
- GI upset
🚨 Serious Side Effects
- GI bleeding
- Hepatotoxicity
- Renal failure
- Stevens-Johnson syndrome
⚠️ Rare Side Effects
- Blood dyscrasias
- Anaphylaxis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Lithium | Major | Increased lithium levels |
| Aspirin | Major | Increased risk of GI ulceration |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Diuretics | Moderate | Reduced diuretic efficacy |
| Anticoagulants | Moderate | Increased INR |
| SSRIs | Moderate | Increased bleeding risk |
| Antacids | Minor | Reduced absorption of aceclofenac |
| Cholestyramine | Minor | Reduced absorption of paracetamol |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Lithium
- Aspirin
⚡ Moderate Interactions
- ACE inhibitors
- Diuretics
- Anticoagulants
- SSRIs
ℹ️ Minor Interactions
- Antacids
- Cholestyramine
🍽️ Food Interactions
Food may delay absorption; avoid alcohol.
🍷 Alcohol Interaction
Increased risk of hepatotoxicity (paracetamol) and GI bleeding (aceclofenac).
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy, history of asthma with NSAIDs.
📊 Monitoring Parameters
Liver function tests, renal function, CBC, blood pressure.
🤱 Lactation Safety
Caution; paracetamol is safe, aceclofenac may be excreted in small amounts.
💊 Overdose Management
Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for aceclofenac.
⏰ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose.
🛑 Myths vs. Facts about arthrin plus 100 mg/500 mg tablet
- Myth: Generic substitutes of arthrin plus 100 mg/500 mg tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Aceclofenac (100mg) + Paracetamol (500mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of arthrin plus 100 mg/500 mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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