Azisal-CL Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat, or difficulty breathing
- Severe watery diarrhea, bloody diarrhea, or diarrhea with fever and stomach cramps
- A painful rash with blisters, peeling skin, or sores in the mouth or eyes
- Yellowing of the skin or eyes, dark urine, or pale stools
- Fainting, dizziness, or a racing or irregular heartbeat
- Unusual bruising or bleeding
- Reduced urine output or swelling of the legs
- New or worsening muscle weakness or difficulty breathing
If experiencing severe symptoms, call emergency services immediately.
What is aroxim az lb 200mg/250mg tablet used for?
This medicine is a prescription antibiotic tablet that combines cefixime 200 mg and azithromycin 250 mg. It is used to treat certain bacterial infections when a doctor decides that two antibiotics are needed together. It is not for viral infections like the common cold. Take it exactly as prescribed, complete the full course, and avoid alcohol.
- Generic Name: Cefixime (200mg) + Azithromycin (250mg)
- Manufacturer: Aronex Life Sciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 aroxim az lb 200mg/250mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सेफिक्सिम 200 मिलीग्राम और एज़िथ्रोमाइसिन 250 मिलीग्राम का संयोजन है। यह एक प्रिस्क्रिप्शन एंटीबायोटिक है जिसका उपयोग डॉक्टर की सलाह पर कुछ बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है, जैसे सांस की नली का संक्रमण, कान-नाक-गले का संक्रमण, मूत्र मार्ग का संक्रमण, त्वचा का संक्रमण और टाइफाइड जैसी बीमारियाँ। यह दवा वायरल बीमारियों जैसे सर्दी-जुकाम या फ्लू में काम नहीं करती। इसे डॉक्टर के बताए अनुसार पूरा कोर्स करना बहुत जरूरी है, भले ही आपको जल्दी आराम लगने लगे। बिना डॉक्टर की सलाह के इसे न खरीदें और न ही किसी और को दें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में पेट खराब होना, दस्त, जी मिचलाना, उल्टी, पेट दर्द, सिरदर्द और मुँह का स्वाद बदलना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ दिनों में ठीक हो जाते हैं। कभी-कभी त्वचा पर दाने, खुजली, या मुँह और योनि में फंगल संक्रमण हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर चेहरे, होंठ, जीभ या गले में सूजन आए, साँस लेने में तकलीफ हो, तेज बुखार के साथ खून वाला दस्त हो, या त्वचा पर छाले पड़ें, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और पूरा कोर्स पूरा करें। टैबलेट को पानी के साथ पूरा निगलें, चबाएँ नहीं। पेट खराब होने पर इसे भोजन के साथ ले सकते हैं। इस दवा के साथ शराब न पिएँ क्योंकि इससे पेट की तकलीफ और चक्कर बढ़ सकते हैं। अगर आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको किडनी या लिवर की बीमारी है, तो डॉक्टर को जरूर बताएँ। अपने आप दवा की मात्रा न बदलें और न ही दवा बंद करें। एंटासिड के साथ इस दवा को लेने से बचें, कम से कम 2 घंटे का अंतर रखें। दवा को बच्चों से दूर और ठंडी सूखी जगह पर रखें।
💊 aroxim az lb 200mg/250mg tablet Uses & Benefits
[{"condition":"Community-acquired respiratory tract infections","description":"Used in selected cases of bacterial bronchitis, pneumonia, and other lower respiratory infections when a clinician decides that combined antibiotic cover is appropriate.","evidence":"Moderate"},{"condition":"Ear, nose, and throat infections","description":"May be prescribed for bacterial sinusitis, pharyngitis, tonsillitis, or otitis media when a doctor identifies a likely bacterial cause and chooses combination therapy.","evidence":"Moderate"},{"condition":"Urinary tract infections","description":"Cefixime component provides activity against many common urinary pathogens, and the combination may be used in selected complicated or recurrent cases under medical supervision.","evidence":"Moderate"},{"condition":"Skin and soft tissue infections","description":"May be used for certain bacterial skin infections when the doctor judges that the combined spectrum of cefixime and azithromycin is suitable.","evidence":"Limited"},{"condition":"Typhoid fever","description":"Cefixime is active against Salmonella typhi, and azithromycin is also used in some resistant cases; the combination may be chosen by a clinician in specific situations.","evidence":"Limited"}]
Off-label uses: [{"condition":"Mycoplasma genitalium infection","description":"Azithromycin has been used in some treatment regimens, but resistance is common and combination therapy is not standard for this product.","evidence":"Limited"},{"condition":"Chlamydial infection","description":"Azithromycin is used for chlamydia, but cefixime is not active against Chlamydia, so this combination is not a standard regimen for that infection.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Respiratory tract infections, Ear, nose, and throat infections, Urinary tract infections, Skin and soft tissue infections, Typhoid fever
📋 Drug Information
| Generic Name(s) | Cefixime (200mg) + Azithromycin (250mg) |
| Brand Name | aroxim az lb 200mg/250mg tablet |
| Manufacturer | Aronex Life Sciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature, between 15°C and 30°C, in a dry place. Keep it in the original blister pack or container, tightly closed. Protect it from direct sunlight, heat, and moisture. Do not store it in the bathroom or near the kitchen sink. Keep it out of the reach of children and pets. |
| Shelf Life | The shelf life is usually 24 months from the date of manufacture, but the exact expiry date is printed on the pack. Do not use the medicine after the expiry date. Check the pack before taking any dose. If the tablet looks discolored, cracked, or damaged, do not use it and ask your pharmacist for advice. |
| WHO Guideline | Not established from the available information. The World Health Organization does not have a specific recommendation for this fixed-dose combination. Antibiotic choice should follow local guidelines and culture results when available. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research promotes rational antibiotic use and advises against unnecessary combinations. This medicine should only be used when a doctor decides that both antibiotics are needed. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine contains two antibiotics with different mechanisms. Cefixime is a third-generation cephalosporin that binds to penicillin-binding proteins in the bacterial cell wall and blocks the cross-linking of peptidoglycan, which weakens the cell wall and causes the bacteria to die. Azithromycin is a macrolide that binds to the 50S ribosomal subunit and blocks the translocation step of protein synthesis, which stops bacteria from making essential proteins and prevents them from growing and multiplying. Together, these two mechanisms give a broader range of antibacterial activity than either agent alone.
Mechanism Steps
💡 How to Take aroxim az lb 200mg/250mg tablet
Strength: Immediate-release oral tablet containing cefixime 200 mg and azithromycin 250 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this fixed-dose combination is one tablet taken once daily, but the exact dose and duration depend on the type and severity of the infection, your kidney and liver function, and your doctor's judgment. Some doctors may prescribe it once daily for 5 to 7 days, while other infections may need a different schedule. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Never change the dose or stop early without talking to your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this fixed-dose combination. Consult a pediatrician. Children may need different antibiotics or weight-based doses of the individual ingredients, and this tablet is not suitable for all age groups. |
| Elderly Dosage | Older adults may need a lower dose or longer dosing interval, especially if kidney function is reduced. Kidney function naturally declines with age, and cefixime is removed by the kidneys. A doctor may check kidney function before and during treatment. Elderly patients should also be watched for dizziness, falls, and heart rhythm changes, especially if they take other medicines. |
| Renal Impairment | In people with mild kidney impairment, the usual dose may be acceptable. In moderate to severe kidney impairment, the dose of cefixime usually needs to be reduced or the dosing interval lengthened. Azithromycin generally does not need dose adjustment for kidney problems, but the combination should be used with caution. A doctor should check kidney function and decide the exact dose. Do not adjust the dose yourself. |
| Hepatic Impairment | People with mild to moderate liver disease usually do not need a dose change, but they should be monitored for side effects. In severe liver disease, this medicine should be used with caution because azithromycin is partly processed by the liver. A doctor may choose a different antibiotic or monitor liver tests closely. Do not take this medicine without telling your doctor about any liver condition. |
| Maximum Daily Dose | The maximum daily dose for this fixed-dose combination is generally one tablet per day, providing cefixime 200 mg and azithromycin 250 mg. Do not take more than the prescribed dose. Higher doses should only be used if a qualified clinician specifically prescribes them and monitors you closely. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of aroxim az lb 200mg/250mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ergotamine | Major | |
| Amiodarone | Major | |
| Carbamazepine | Major | |
| Digoxin | Moderate | |
| Cyclosporine | Moderate | |
| Theophylline | Moderate | |
| Antacids | Moderate | |
| Oral contraceptives | Minor | |
| Probiotics | Minor |
🚨 Major Interactions
- Warfarin and other blood thinners
- Ergotamine and dihydroergotamine
- Medicines that prolong the QT interval
- Carbamazepine
⚡ Moderate Interactions
- Antacids and proton pump inhibitors
- Digoxin
- Cyclosporine
- Theophylline
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can increase the chance of stomach upset, nausea, and dizziness. It can also put extra stress on the liver, which is already handling azithromycin. In rare cases, alcohol combined with antibiotics may worsen heart rhythm problems. It is best to wait until you have finished the course and your doctor says it is safe before drinking alcohol again.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to cefixime, other cephalosporins, or azithromycin","Previous severe allergic reaction to penicillins or other beta-lactam antibiotics","History of cholestatic jaundice or liver problems caused by azithromycin","Use of ergotamine or dihydroergotamine","Severe kidney disease without dose adjustment by a doctor","Myasthenia gravis, because azithromycin can worsen muscle weakness"]
⚠️ Warnings & Precautions
["Tell your doctor if you are allergic to penicillin or other antibiotics before taking this medicine.","Use with caution in people with kidney or liver disease; dose adjustment may be needed.","Avoid alcohol during treatment because it can worsen side effects.","Do not use this medicine for viral infections such as colds or flu.","Complete the full course even if you feel better to prevent resistance.","Watch for severe diarrhea, which may be a sign of a serious bowel infection.","Tell your doctor if you have heart rhythm problems or take medicines that affect heart rhythm.","This medicine may make you dizzy; avoid driving or operating machinery until you know how it affects you.","Do not share this medicine with others.","Keep out of reach of children."]
🤱 Lactation Safety
Both cefixime and azithromycin pass into breast milk in small amounts. They are generally considered compatible with breastfeeding, but the baby should be watched for diarrhea, thrush, or rash. If you are breastfeeding and your doctor prescribes this medicine, ask whether you should feed the baby just before taking the dose to reduce the amount in milk. Always consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
If you take too much of this medicine, contact your doctor or go to the nearest emergency department immediately. Take the medicine pack with you so the medical team knows exactly what you took. Overdose may cause severe nausea, vomiting, diarrhea, stomach pain, dizziness, or changes in heart rhythm. Treatment is supportive and may include fluids, monitoring of vital signs, and an ECG. There is no specific antidote for this combination. Do not try to make yourself vomit unless a medical professional tells you to.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, call your doctor or pharmacist. Try to take the medicine at the same time each day to keep steady levels in your body.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, at the same time each day, and complete the full course even if you feel better. Swallow the tablet whole with a glass of water. Taking it with food can reduce stomach upset. Do not crush, chew, or break the tablet unless your doctor or pharmacist tells you to. Do not share this medicine with anyone else, even if they have similar symptoms. Do not save leftover antibiotics for later use. Tell your doctor about all other medicines, vitamins, and herbal products you take, because this medicine can interact with some of them. Avoid alcohol while taking this medicine because it can worsen stomach upset and dizziness. If you are pregnant, planning pregnancy, or breastfeeding, speak to your doctor before taking this medicine. If you have kidney or liver problems, your doctor may need to adjust the dose or monitor you more closely. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose. Never double the dose. Keep this medicine out of the reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to have reduced kidney function, heart disease, and other medical conditions. Cefixime is removed by the kidneys, so the dose may need to be reduced. Azithromycin can affect heart rhythm, especially in people with existing heart problems or low electrolyte levels. Elderly patients should be monitored for dizziness, falls, confusion, and diarrhea. A doctor may check kidney function and electrolytes before and during treatment.
🤰 Pregnancy Planning (TTC)
If you are trying to conceive, tell your doctor before taking this medicine. Both cefixime and azithromycin are generally considered acceptable in pregnancy when prescribed for a clear bacterial infection, but this combination should only be used if needed. If you become pregnant while taking this medicine, contact your doctor right away. Do not start or stop any antibiotic without medical advice when you are planning pregnancy.
🏥 Post-Surgery Considerations
This medicine may be prescribed after some surgical procedures if a bacterial infection is suspected or to treat a known infection. It is not a routine preventive antibiotic for all surgeries. If you have had surgery and develop fever, redness, swelling, or discharge from the wound, contact your surgeon. Tell your surgical team about all medicines you take, including this one, before any operation.
🦷 Dental Procedures
Tell your dentist if you are taking this medicine before any dental procedure. Antibiotics can affect the normal bacteria in the mouth and may increase the risk of fungal infections such as oral thrush. If you need dental work while taking this medicine, your dentist may advise you to continue or adjust the timing. Do not stop the antibiotic without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can continue light activities if you feel well, but avoid strenuous exercise while you are recovering from an infection. If you feel dizzy, weak, or short of breath, rest and do not push yourself. People with heart conditions should be especially careful because azithromycin can rarely affect heart rhythm. Ask your doctor when you can return to your normal exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Most people can continue their usual work and daily activities while taking this medicine. However, some people may feel dizzy, tired, or have stomach upset. If you feel dizzy or drowsy, avoid driving, operating heavy machinery, or doing tasks that need full alertness until you know how the medicine affects you. Take your dose at a time that fits your routine, such as with breakfast, so you do not forget it. If your work involves close contact with others, follow hygiene measures to avoid spreading infection.
🛑 When to Stop This Medicine
Do not stop this medicine early unless your doctor tells you to. Complete the full course even if you feel better. You should stop the medicine and contact your doctor immediately if you develop a severe allergic reaction, a widespread blistering rash, severe or bloody diarrhea, yellowing of the skin or eyes, or an irregular heartbeat. If you have severe side effects that make it hard to continue, call your doctor before stopping so they can advise you on the best course of action.
📅 Long-Term Use Effects
This medicine is usually prescribed for a short course, so long-term effects are not common. However, repeated or prolonged use of antibiotics can lead to antibiotic resistance, gut bacteria imbalance, and a higher risk of fungal infections such as oral thrush or vaginal yeast infection. Rarely, azithromycin can affect the heart rhythm or liver with long-term use. If you need repeated courses of antibiotics, your doctor should review the underlying cause and may check your kidney and liver function. Do not use this medicine for longer than prescribed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
May be enough for some infections and avoids the extra antibiotic.
Evidence: Well-establishedMay be enough for certain respiratory or skin infections.
Evidence: Well-establishedAnother antibiotic option for some bacterial infections.
Evidence: Well-establishedImportant for recovery, but does not replace antibiotics for bacterial infections.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Antibiotics do not interfere with most vaccines, but if you are unwell with a fever, your doctor may advise waiting until you recover before getting vaccinated. Live vaccines should generally be avoided during acute illness. If you are due for a vaccine, tell the nurse or doctor that you are taking this medicine. There is no specific vaccine interaction established for this combination.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless the label says so
✅ DO
Keep in the original blister pack or container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children and pets
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label visible. Bring a copy of your prescription and a doctor's note if you are travelling internationally. Keep the medicine in your hand luggage, not in checked baggage, so it stays with you and is not exposed to extreme temperatures. Store it at room temperature and away from direct sunlight. If you are crossing time zones, ask your doctor how to adjust the timing of your doses. Check the customs rules of your destination country for prescription medicines. Do not pack it loosely with other items where it could get crushed or mixed up.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 24 to 72 hours, but some symptoms such as cough can take longer to settle. Complete the full course as prescribed.
A: Yes, you can take it with food. Taking it with a meal can reduce stomach upset.
A: Take the missed dose as soon as you remember, unless it is almost time for the next dose. If it is almost time, skip the missed dose and continue your regular schedule. Do not double the dose.
A: It is best to avoid alcohol during treatment because it can worsen stomach upset, dizziness, and liver stress.
A: Both ingredients are generally considered acceptable in pregnancy when prescribed by a doctor, but this combination should only be used if clearly needed. Do not self-medicate.
A: No. You should complete the full course prescribed by your doctor to prevent the infection from returning and to reduce the risk of antibiotic resistance.
🤔 Common Patient Concerns
🔄 Substitutes for aroxim az lb 200mg/250mg tablet
View AllAlternative brands with exact same active ingredient:
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cefivot az kid tabletVotary Laboratories I Ltd ₹92.81 58.8% CHEAPER
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ceficheck az 200mg/250mg tabletHilbert Healthcare ₹92.81 58.8% CHEAPER
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aelxim-az 200mg/250mg tabletAllenge India ₹93.38 58.5% CHEAPER
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Setxim AZ 200mg/250mg TabletAtyad Life Sciences Pvt Ltd ₹99.00 56% CHEAPER
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zytax-az 200mg/250mg tabletZodley Pharmaceuticals Pvt Ltd ₹99.60 55.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure the common cold and flu.
Fact: Colds and flu are caused by viruses, and this medicine only works against bacteria. Taking it for a viral illness does not help and can cause side effects and resistance. - Myth: You can stop antibiotics as soon as you feel better.
Fact: You should complete the full course prescribed by your doctor. Stopping early can allow the infection to come back and can lead to antibiotic resistance. - Myth: Two antibiotics are always better than one.
Fact: Combining antibiotics is only helpful in selected situations. Unnecessary combinations increase side effects, cost, and resistance. - Myth: Antibiotics weaken your immune system permanently.
Fact: Antibiotics do not permanently weaken the immune system, but they can disturb the normal bacteria in the gut for a short time.
🔄 Alternative Options
Generic Alternatives
- Cefixime 200 mg + Azithromycin 250 mg tablet
Brand Alternatives
- Azisal-CL Tablet