arocef 200mg tablet - Cefpodoxime Proxetil (200mg) medicine

Arocef 200mg Tablet - Uses, Price, Side Effects, and Dosage

4.5 (8 reviews)

Cefpodoxime Proxetil (200mg)

🏭 Intra Labs India Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is arocef 200mg tablet used for?

Arocef 200mg Tablet contains Cefpodoxime Proxetil, a cephalosporin antibiotic that fights bacteria by inhibiting cell wall synthesis. It is used to treat respiratory tract infections (like pneumonia, bronchitis), urinary tract infections, skin infections, and ear infections. It works best when taken at evenly spaced intervals, usually twice daily, with or without food.

Generic Name: Cefpodoxime Proxetil
Manufacturer: Intra Labs India Pvt Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 arocef 200mg tablet Uses & Benefits

Treatment of respiratory tract infections (e.g., community-acquired pneumonia, acute exacerbations of chronic bronchitis), urinary tract infections, skin and soft tissue infections, otitis media, sinusitis, and uncomplicated gonorrhea.

Off-label uses: Lyme disease, Meningococcal prophylaxis, Bacterial endocarditis prophylaxis

📋 Drug Information

Generic Name(s)	Cefpodoxime Proxetil
Brand Name	Axone O 200mg Tablet
Manufacturer	Intra Labs India Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI INFECTIVES
Action Class	Cephalosporins: 3 generation
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from gastrointestinal tract; absorption is enhanced by food.

DistributionDistributes widely into body tissues and fluids including lungs, tonsils, prostate, and middle ear; crosses placenta and enters breast milk.

Protein BindingAbout 21-29% bound to plasma proteins.

MetabolismCefpodoxime proxetil is de-esterified to active cefpodoxime; further metabolism is minimal.

Half-LifeApproximately 2-3 hours in patients with normal renal function.

ExcretionPrimarily excreted unchanged in urine via glomerular filtration and tubular secretion.

BioavailabilityApproximately 50% (increased to 60-70% when taken with food).

Onset of ActionRapid; within 1-2 hours after oral administration.

Peak Plasma Time2-3 hours after oral administration.

Duration of ActionApproximately 12 hours.

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and death.

Mechanism Steps

1Cefpodoxime proxetil is de-esterified by intestinal esterases to active cefpodoxime.

2Cefpodoxime binds to penicillin-binding proteins (PBPs) located on the bacterial cell wall.

3Inhibition of transpeptidase enzymes prevents cross-linking of peptidoglycan chains.

💡 How to Take arocef 200mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of arocef 200mg tablet

✅ Common Side Effects

Diarrhea
Nausea
Vomiting
Abdominal pain
Headache
Vaginal candidiasis

🚨 Serious Side Effects

Pseudomembranous colitis
Severe allergic reactions (anaphylaxis)
Stevens-Johnson syndrome
Toxic epidermal necrolysis
Seizures

⚠️ Rare Side Effects

Hemolytic anemia
Agranulocytosis
Thrombocytopenia
Interstitial nephritis
Hepatitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Probenecid	Moderate	Increased cefpodoxime levels
Antacids	Moderate	Reduced absorption of cefpodoxime

🚨 Major Interactions

Probenecid
Warfarin
Live typhoid vaccine

⚡ Moderate Interactions

BCG vaccine
Cholera vaccine
Estrogen derivatives
Sodium picosulfate

ℹ️ Minor Interactions

Antacids
H2-receptor antagonists
Iron supplements

🍽️ Food Interactions

Food increases absorption; avoid concurrent administration with antacids or iron supplements.

🍷 Alcohol Interaction

No direct interaction reported; however, alcohol may reduce immune response and increase side effects.

🛡️ Safety & Warnings

Liver

Low

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to cefpodoxime or other cephalosporins; history of immediate-type hypersensitivity to penicillins.

📊 Monitoring Parameters

Renal function (especially in elderly or renally impaired), signs of superinfection, prothrombin time if on warfarin.

🤱 Lactation Safety

Excreted in breast milk in small amounts; use with caution.

💊 Overdose Management

Supportive care; hemodialysis may enhance elimination.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose and resume regular schedule. Do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for arocef 200mg tablet

View All

Alternative brands with exact same active ingredient (Cefpodoxime Proxetil (200mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.