aricoff junior syrup - Phenylephrine (5mg) + Chlorpheniramine Maleate (2mg) medicine

Aricoff Junior Syrup - Uses, Price, Side Effects

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๐Ÿญ Aries Drugs Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is aricoff junior syrup used for?

Aricoff Junior Syrup is a combination medicine used to relieve symptoms of the common cold and allergies in children. It contains Phenylephrine, a decongestant that reduces nasal congestion, and Chlorpheniramine Maleate, an antihistamine that blocks histamine to relieve sneezing, runny nose, and watery eyes. It works by shrinking blood vessels in the nasal passages and blocking allergic reactions.

  • Generic Name: Phenylephrine + Chlorpheniramine Maleate
  • Manufacturer: Aries Drugs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š aricoff junior syrup Uses & Benefits

Allergic rhinitis, Common cold, Sinusitis

๐Ÿ“‹ Drug Information

Generic Name(s)Phenylephrine + Chlorpheniramine Maleate
Brand NameAscoril D Plus Syrup Sugar Free
ManufacturerAries Drugs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassDecongestant + Antihistamine
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from gastrointestinal tract
DistributionDistributes widely; crosses blood-brain barrier
Protein BindingPhenylephrine: low; Chlorpheniramine: 70%
MetabolismPhenylephrine: hepatic (MAO); Chlorpheniramine: hepatic (CYP450)
Half-LifePhenylephrine: 2-3 hours; Chlorpheniramine: 12-15 hours
ExcretionRenal (urine)
BioavailabilityPhenylephrine: ~38%; Chlorpheniramine: ~25-50%
Onset of ActionPhenylephrine: 15-30 min; Chlorpheniramine: 30-60 min
Peak Plasma TimePhenylephrine: 1-2 hours; Chlorpheniramine: 2-6 hours
Duration of ActionPhenylephrine: 4-6 hours; Chlorpheniramine: 4-6 hours

How It Works

Phenylephrine: alpha-1 adrenergic agonist causing vasoconstriction; Chlorpheniramine: H1 receptor antagonist blocking histamine effects

Mechanism Steps

1Phenylephrine binds to alpha-1 adrenergic receptors on vascular smooth muscle
2Causes vasoconstriction in nasal mucosa, reducing congestion
3Chlorpheniramine blocks H1 receptors on blood vessels and respiratory epithelium

๐Ÿ’ก How to Take aricoff junior syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of aricoff junior syrup

โœ… Common Side Effects

  • Drowsiness
  • Dry mouth
  • Nausea
  • Dizziness
  • Headache

๐Ÿšจ Serious Side Effects

  • Hypertension
  • Arrhythmias
  • Seizures
  • Urinary retention

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Thrombocytopenia
  • Hallucinations

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Hypertensive crisis
Beta-blockers Moderate Reduced antihypertensive effect
CNS depressants Moderate Increased sedation

๐Ÿšจ Major Interactions

  • MAOIs
  • Beta-blockers
  • Tricyclic antidepressants

โšก Moderate Interactions

  • Antihypertensives
  • Sympathomimetics
  • CNS depressants

โ„น๏ธ Minor Interactions

  • Antacids
  • Caffeine

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase chlorpheniramine levels

๐Ÿท Alcohol Interaction

Increased CNS depression

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Moderate
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypertension, Hyperthyroidism, Diabetes, Glaucoma, MAOI use, Severe coronary artery disease

๐Ÿ“Š Monitoring Parameters

Blood pressure, Heart rate, CNS effects

๐Ÿคฑ Lactation Safety

Caution; may be excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; may include activated charcoal, benzodiazepines for seizures

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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