arichlor 200mg tablet - Hydroxychloroquine (200mg) medicine

Hydroxychloroquine 200mg Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 Arlak Biotech Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for rheumatoid arthritis, lupus, and malaria; moderate for Sjögren's syndrome.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blurred vision or any changes in eyesight
  • Chest pain, shortness of breath, or irregular heartbeat
  • Severe skin rash with blistering or peeling
  • Unusual bruising or bleeding
  • Yellowing of skin or eyes (jaundice)
  • Severe abdominal pain or persistent vomiting
  • Signs of low blood sugar: shakiness, sweating, confusion

If experiencing severe symptoms, call emergency services immediately.

What is arichlor 200mg tablet used for?

Hydroxychloroquine 200mg tablet is a disease-modifying antirheumatic drug (DMARD) used to treat autoimmune conditions like rheumatoid arthritis and lupus, and to prevent and treat malaria. It works by modulating the immune system and reducing inflammation. It requires regular monitoring for eye and heart side effects.

  • Generic Name: Hydroxychloroquine (200mg)
  • Manufacturer: Arlak Biotech Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 arichlor 200mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा हाइड्रॉक्सीक्लोरोक्वीन 200mg युक्त है और मुख्य रूप से रूमेटॉयड आर्थराइटिस, ल्यूपस, और मलेरिया के इलाज में उपयोग की जाती है। यह शरीर की प्रतिरक्षा प्रणाली को नियंत्रित करके सूजन और दर्द को कम करती है। यह दवा धीरे-धीरे काम करती है और इसका पूरा असर होने में कई सप्ताह लग सकते हैं। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, पेट दर्द, सिरदर्द, चक्कर आना और त्वचा पर दाने शामिल हैं। गंभीर दुष्प्रभावों में आंखों की रोशनी पर असर, दिल की समस्या, और खून की बीमारियां हो सकती हैं। नियमित जांच कराते रहें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लेने से पेट की परेशानी कम हो सकती है। आंखों की नियमित जांच कराएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। शराब का सेवन न करें। दवा को बंद करने से पहले डॉक्टर से परामर्श करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 arichlor 200mg tablet Uses & Benefits

[{"condition":"Rheumatoid arthritis","description":"Used as a disease-modifying antirheumatic drug to reduce joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and progression of joint damage.","evidence":"Well-established"},{"condition":"Systemic lupus erythematosus","description":"Helps control skin rash, joint pain, fatigue, and other symptoms, and reduces flare frequency.","evidence":"Well-established"},{"condition":"Malaria","description":"Used for treatment and prevention of malaria caused by susceptible strains of Plasmodium species.","evidence":"Well-established"},{"condition":"Sjögren's syndrome","description":"May help relieve dry eyes, dry mouth, joint pain, and fatigue in some patients.","evidence":"Moderate"},{"condition":"Discoid lupus erythematosus","description":"Effective for skin lesions and photosensitivity associated with discoid lupus.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Porphyria cutanea tarda","description":"Sometimes used off-label to reduce skin blistering and liver enzyme abnormalities.","evidence":"Limited"},{"condition":"Sarcoidosis","description":"May be used off-label for skin and joint involvement, but evidence is limited.","evidence":"Limited"},{"condition":"Q fever","description":"Occasionally used as part of combination therapy for chronic Q fever.","evidence":"Limited"}]

Primary treatment for: Rheumatoid arthritis

Also treats: Systemic lupus erythematosus, Malaria, Sjögren's syndrome, Discoid lupus erythematosus

📋 Drug Information

Generic Name(s)Hydroxychloroquine (200mg)
Brand Namearichlor 200mg tablet
ManufacturerArlak Biotech Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassDisease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineHydroxychloroquine is included in WHO essential medicines list for malaria and autoimmune conditions. Specific recommendations vary by region and condition.
ICMR GuidelineICMR guidelines recommend hydroxychloroquine for rheumatoid arthritis and lupus as a DMARD, with regular monitoring. For malaria, it is used in areas with chloroquine-sensitive Plasmodium vivax.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Get a baseline eye examination before starting and then annually after 5 years of use.
3
Report any vision changes, such as blurred vision or difficulty seeing at night, immediately.
4
Do not stop taking this medicine suddenly without consulting your doctor.
5
Inform your doctor if you have diabetes, as this medicine can cause low blood sugar.
6
Avoid alcohol while taking this medicine to reduce the risk of liver problems.
7
Use effective contraception if you are of childbearing age and discuss pregnancy plans with your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain and swelling
This medicine is commonly prescribed for rheumatoid arthritis.
Likely Use
✅
Skin rash with photosensitivity
Used for lupus skin manifestations.
Likely Use
❌
Fever with chills
This medicine is not a primary fever reducer; it is used for malaria prevention/treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionHydroxychloroquine is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration. The bioavailability is approximately 74% due to first-pass metabolism. Food does not significantly affect absorption.
DistributionIt has a large volume of distribution (approximately 5,000-10,000 L) and is extensively distributed into tissues, including the liver, spleen, kidneys, lungs, and melanin-containing tissues such as the eyes and skin. It crosses the placenta and is excreted in breast milk.
Protein BindingApproximately 45% bound to plasma proteins.
MetabolismPartially metabolized in the liver by cytochrome P450 enzymes, primarily CYP2D6, CYP3A4, and CYP2C8, to active metabolites including desethylhydroxychloroquine.
Half-LifeThe terminal elimination half-life is long, ranging from 20 to 60 days, which allows for once-daily dosing but also means that side effects may persist after stopping the medicine.
ExcretionPrimarily excreted in urine (about 20-25% unchanged) and in feces. Renal clearance is significant, and dose adjustment may be needed in renal impairment.
BioavailabilityApproximately 74%.
Onset of ActionFor malaria, onset is within hours to days. For autoimmune conditions, clinical improvement may take 4 to 12 weeks, with full effects sometimes taking up to 6 months.
Peak Plasma TimePeak plasma concentrations are reached within 1 to 3 hours after oral administration.
Duration of ActionThe effects are long-lasting due to the long half-life, but therapeutic effects in autoimmune diseases require continuous administration. The duration of action for a single dose is not well-defined for chronic conditions.

How It Works

Hydroxychloroquine is a weak base that accumulates in lysosomes and raises their pH. This interferes with antigen processing and presentation, thereby dampening T-cell activation and reducing the production of pro-inflammatory cytokines such as tumor necrosis factor-alpha and interleukin-6. It also inhibits toll-like receptor signaling, which is involved in autoimmune responses. In malaria, it concentrates in the food vacuole of the parasite and prevents the polymerization of toxic heme into hemozoin, leading to parasite death. Additionally, it has mild immunomodulatory effects on B cells and can reduce the formation of autoantibodies.

Mechanism Steps

1
Lysosomal accumulation: Hydroxychloroquine enters cells and accumulates in lysosomes due to its weak base properties, raising lysosomal pH.
2
Inhibition of antigen processing: The increased pH impairs the activity of lysosomal enzymes, reducing the processing and presentation of antigens to T cells.
3
Suppression of immune activation: This leads to decreased T-cell activation and reduced production of pro-inflammatory cytokines, dampening the autoimmune response.
4
Inhibition of toll-like receptors: It also blocks TLR7 and TLR9 signaling, which are involved in recognizing nucleic acids and triggering inflammation in autoimmune diseases.
5
Antimalarial action: In malaria parasites, it prevents the polymerization of toxic heme into hemozoin, causing accumulation of toxic heme and parasite death.

💡 How to Take arichlor 200mg tablet

Strength: 200mg immediate-release tablet

1Take the tablet orally with a full glass of water.
2You may take it with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush, chew, or break it.
4Take it at the same time each day to maintain consistent levels.
5If you miss a dose, follow the missed dose instructions.
6Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe dose of this medicine must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. For rheumatoid arthritis, a typical starting dose is 400-600 mg daily, which may be reduced to 200-400 mg daily for maintenance. For lupus, 200-400 mg daily is common. For malaria treatment, doses vary by region and strain. Always follow your doctor's prescription exactly.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to side effects, especially retinopathy and cardiac effects. Dose should be individualized by a clinician, and regular monitoring is essential.
Renal ImpairmentDose adjustment may be necessary in renal impairment. Consult your doctor for personalized dosing.
Hepatic ImpairmentUse with caution in hepatic impairment. Dose adjustment may be needed. Consult your doctor.
Maximum Daily DoseThe maximum daily dose varies by indication and is determined by your doctor. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of arichlor 200mg tablet

✅ Common Side Effects

Nausea (Common (up to 10%))
Take with food or milk to reduce nausea. If it persists, consult your doctor.
Abdominal cramps (Common (5-10%))
Try taking with meals. If severe, contact your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if it persists.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Skin rash (Common (5-10%))
If rash is mild, monitor. If it spreads or is accompanied by fever, seek medical attention.

🚨 Serious Side Effects

Retinopathy (eye damage) (Uncommon (1-10% with long-term use))
Get regular eye exams. Report any vision changes immediately.
Cardiomyopathy (Rare (<0.1%))
Seek immediate care if you experience chest pain, shortness of breath, or swelling in legs.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Rare (<0.1%))
Stop the medicine and seek emergency care if you develop blistering, peeling skin, or sores in mouth.
Blood disorders (e.g., agranulocytosis, thrombocytopenia) (Rare (<0.1%))
Report unusual bruising, bleeding, or signs of infection to your doctor.
Liver toxicity (Rare (<0.1%))
Report yellowing of eyes or skin, dark urine, or severe abdominal pain.

⚠️ Rare Side Effects

Seizures
Seek emergency medical attention.
Hypoglycemia
Monitor blood sugar if diabetic. Report symptoms like shakiness, sweating, confusion.
Psychiatric disturbances
Report mood swings, depression, or hallucinations to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Digoxin Major
Methotrexate Major
Insulin Major
Amiodarone Major
Antacids Moderate
Cimetidine Moderate
Rifampicin Moderate
Ampicillin Minor
Neostigmine Minor
Warfarin Moderate

🚨 Major Interactions

  • Digoxin
  • Methotrexate
  • Antidiabetic drugs (e.g., insulin, sulfonylureas)
  • QT-prolonging drugs (e.g., amiodarone, sotalol)

⚡ Moderate Interactions

  • Antacids
  • Cimetidine
  • Rifampicin

🍷 Alcohol Interaction

Alcohol may increase the risk of liver toxicity and stomach bleeding. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to hydroxychloroquine or any component of the formulation","Pre-existing retinopathy or visual field changes","Use in children for long-term treatment of juvenile idiopathic arthritis (except under specialist care)","Concurrent use with drugs that prolong QT interval (relative)","Severe renal impairment (relative)"]

⚠️ Warnings & Precautions

["Perform baseline and periodic eye examinations to detect retinopathy early.","Use with caution in patients with liver disease, alcoholism, or concurrent hepatotoxic drugs.","May cause hypoglycemia; monitor blood glucose in diabetics.","May prolong QT interval; use caution in patients with cardiac disease or electrolyte imbalances.","Avoid in patients with porphyria or psoriasis as it may exacerbate these conditions.","Do not use for long-term treatment of children unless under specialist supervision.","May impair mental alertness; avoid driving if affected."]

🤱 Lactation Safety

Hydroxychloroquine passes into breast milk in small amounts. It is generally considered compatible with breastfeeding, but consult your doctor to weigh benefits and risks.

💊 Overdose Management

Overdose can be life-threatening, causing cardiac arrhythmias, hypotension, seizures, and respiratory depression. Seek emergency medical care immediately. Treatment is supportive and may include activated charcoal, gastric lavage, and management of arrhythmias. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet unless your doctor advises otherwise. Swallow it whole with a glass of water. You may take it with food or milk to reduce stomach upset. Do not stop taking this medicine suddenly without consulting your doctor, as this can worsen your condition. Keep all scheduled appointments for eye exams, blood tests, and heart checks. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Avoid alcohol while taking this medicine as it may increase the risk of liver problems. Do not drive or operate heavy machinery if you feel dizzy or have blurred vision. Store this medicine in a cool, dry place away from direct sunlight and out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of retinopathy and cardiac side effects. Regular monitoring is essential. Dose may need adjustment based on kidney function.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor. Hydroxychloroquine may be continued if benefits outweigh risks. Use effective contraception if not planning pregnancy.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may affect wound healing and increase risk of bleeding. Your doctor may advise temporary discontinuation.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may increase risk of bleeding and infection. Your dentist may recommend antibiotic prophylaxis for certain procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming or walking.
😴
Practice good posture and joint protection techniques.
💧
Include anti-inflammatory foods like omega-3 rich fish, fruits, and vegetables.
🧘
Get adequate sleep to support immune function.
🌞
Use sunscreen and protective clothing to manage photosensitivity.

🏋️ Exercise Considerations

Moderate exercise is encouraged, but avoid high-impact activities that stress joints. If you experience dizziness or muscle weakness, consult your doctor before continuing.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated
Limit alcohol
Avoid grapefruit

💼 Impact on Daily Work & Life

This medicine may cause dizziness or blurred vision in some people. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities, but fatigue and joint pain may require adjustments.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects like vision changes, chest pain, or severe rash, seek immediate medical attention and follow your doctor's advice on whether to stop.

📅 Long-Term Use Effects

Long-term use requires regular monitoring for retinopathy, cardiomyopathy, and blood disorders. The risk of eye damage increases with duration and cumulative dose. Annual eye exams are recommended after 5 years of use. Liver and kidney function should be checked periodically. Do not stop without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve joint function.

Evidence: Well-established
Dietary changes

Anti-inflammatory diet may help reduce symptoms.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Hydroxychloroquine may impair immune response to vaccines. Consult your doctor about timing of vaccinations, especially live vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. For air travel, keep it in your carry-on luggage. If crossing time zones, adjust dosing times gradually in consultation with your doctor. Store at room temperature and avoid extreme heat or cold. Check customs regulations for restricted medicines in your destination country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old woman with rheumatoid arthritis
She started this medicine as prescribed. After 8 weeks, her joint pain and swelling significantly reduced. She experienced mild nausea initially, which subsided when she took the tablet with breakfast. She continues regular eye check-ups.
💡 Lesson: Consistent use and taking with food improves tolerability and effectiveness.
👤 A 32-year-old man with systemic lupus erythematosus
He was prescribed this medicine for skin rash and joint pain. Within 3 months, his rash cleared and fatigue improved. He was advised to use sunscreen and avoid alcohol. He reports no side effects.
💡 Lesson: Long-term adherence and lifestyle modifications are key to managing lupus.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: For autoimmune conditions, it may take 4-12 weeks to see improvement, with full effects in up to 6 months. For malaria, it works within hours to days.

Q: Can I take this medicine if I am pregnant?

A: Consult your doctor. It may be used if clearly needed, but risks and benefits must be weighed.

Q: What should I avoid while taking this medicine?

A: Avoid alcohol, grapefruit, and antacids within 4 hours of dosing. Also avoid driving if you feel dizzy.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for arichlor 200mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Hydroxychloroquine is a painkiller.
    Fact: It is not a painkiller; it works slowly to modify the disease process and reduce inflammation.
  • Myth: Hydroxychloroquine is safe for everyone.
    Fact: It can cause serious side effects and is not suitable for people with certain eye, heart, or blood conditions.
  • Myth: You can stop hydroxychloroquine once you feel better.
    Fact: Stopping suddenly can cause flare-ups. Always consult your doctor before stopping.

🔄 Alternative Options

Generic Alternatives

  • Hydroxychloroquine sulfate 200mg tablet

Brand Alternatives

  • Alaquin 200mg tablet
  • HCQS 200mg tablet
  • Zy-Q 200mg tablet
  • Hydroxychloroquine 200mg tablet (various manufacturers)

📊 Comparison with Similar Medicines

[{"medicine":"Hydroxychloroquine","class":"DMARD/Antimalarial","main_use":"RA, lupus, malaria","route":"Oral","half_life":"20-60 days"},{"medicine":"Chloroquine","class":"Antimalarial","main_use":"Malaria, RA","route":"Oral","half_life":"20-60 days"},{"medicine":"Methotrexate","class":"DMARD","main_use":"RA, psoriasis","route":"Oral, injection","half_life":"3-10 hours"}]

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