arepar 650mg tablet - Uses, Price, Side Effects & Substitutes
What is arepar 650mg tablet used for?
Action or 1000mg Tablet (Paracetamol) is used to treat PAIN ANALGESICS. It contains Paracetamol (650mg), which Inhibits cyclooxygenase (COX) in the central nervous system, reducing prostaglan. Always consult your doctor before use. Take as prescribed.
- Generic Name: Paracetamol
- Manufacturer: Aeryn Lifesciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ arepar 650mg tablet Uses & Benefits
๐ Drug Information
| Generic Name(s) | Paracetamol |
| Brand Name | Action or 1000mg Tablet |
| Manufacturer | Aeryn Lifesciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Analgesic & Antipyretic-PCM |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30ยฐC); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits cyclooxygenase (COX) in the central nervous system, reducing prostaglandin synthesis; also activates descending serotonergic pathways.
Mechanism Steps
๐ก How to Take arepar 650mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of arepar 650mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Constipation
- Rash
๐จ Serious Side Effects
- Hepatotoxicity
- Acute liver failure
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Acute generalized exanthematous pustulosis
โ ๏ธ Rare Side Effects
- Thrombocytopenia
- Leukopenia
- Neutropenia
- Pancreatitis
- Hypersensitivity reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk with high doses of paracetamol |
| Alcohol | Major | Increased hepatotoxicity risk |
| Isoniazid | Major | Increased hepatotoxicity risk |
| Rifampin | Major | Reduced paracetamol efficacy; increased hepatotoxicity |
| Carbamazepine | Major | Reduced paracetamol efficacy; increased hepatotoxicity |
| Phenytoin | Major | Reduced paracetamol efficacy; increased hepatotoxicity |
| Barbiturates | Major | Reduced paracetamol efficacy; increased hepatotoxicity |
| Cholestyramine | Moderate | Reduced absorption of paracetamol |
| Metoclopramide | Moderate | Increased absorption rate of paracetamol |
| Domperidone | Moderate | Increased absorption rate of paracetamol |
| Probenecid | Moderate | Reduced clearance of paracetamol |
| Oral contraceptives | Moderate | Reduced analgesic effect of paracetamol |
| Caffeine | Minor | Enhanced analgesic effect |
| Zidovudine | Minor | Increased risk of neutropenia |
| Lamotrigine | Minor | Reduced lamotrigine efficacy |
๐จ Major Interactions
- Warfarin
- Alcohol (chronic heavy use)
- Isoniazid
- Rifampin
- Carbamazepine
- Phenytoin
- Barbiturates
โก Moderate Interactions
- Cholestyramine
- Metoclopramide
- Domperidone
- Probenecid
- Oral contraceptives
โน๏ธ Minor Interactions
- Caffeine
- Zidovudine
- Lamotrigine
๐ฝ๏ธ Food Interactions
Food may delay absorption; high-fat meals reduce peak concentration.
๐ท Alcohol Interaction
Chronic heavy alcohol use increases hepatotoxicity risk; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to paracetamol; severe hepatic impairment; chronic alcoholism.
๐ Monitoring Parameters
Liver function tests (in overdose or chronic high doses); renal function in long-term use.
๐คฑ Lactation Safety
Excreted in breast milk in small amounts; considered safe at therapeutic doses.
๐ Overdose Management
Activated charcoal if within 1 hour; N-acetylcysteine (NAC) as antidote; monitor liver function.
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for arepar 650mg tablet
View AllAlternative brands with exact same active ingredient (Paracetamol (650mg)):
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alice 650mg tabletInd Swift Laboratories Ltd โน3.31 81.4% CHEAPER
-
anglopar 650 tabletAnglo-French Drugs & Industries Ltd โน4.51 74.7% CHEAPER
-
paranir 650mg tabletNirlife Healthcare โน5.32 70.1% CHEAPER
-
parapil 650mg tabletPsychotropics India Ltd โน5.86 67.1% CHEAPER
-
doliprane 650mg tabletAbbott โน6.61 62.9% CHEAPER
-
cofamol 650mg tabletAdcock Ingram Healthcare Pvt Ltd โน6.90 61.3% CHEAPER
-
merimol 650mg tablet dtWockhardt Ltd โน7.03 60.5% CHEAPER
-
flumol 650mg tabletElder Pharmaceuticals Ltd โน7.25 59.3% CHEAPER
-
pyrexon 650mg tabletWockhardt Ltd โน7.79 56.3% CHEAPER
-
bactpar 650mg tabletBactolac Formulations Pvt Ltd โน7.97 55.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.