arelol 25mg tablet sr - Metoprolol Succinate (25mg) medicine

Aimet 25mg Tablet XR: Complete Medicine Guide

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🏭 Aretaeus Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Very slow heartbeat (less than 50 beats per minute)
  • Difficulty breathing or wheezing
  • Sudden weight gain or swelling of ankles or feet
  • Chest pain or worsening angina
  • Severe allergic reaction (rash, itching, swelling of face, lips, or throat)
  • Unusual bruising or bleeding
  • Yellowing of skin or eyes (jaundice)

If experiencing severe symptoms, call emergency services immediately.

What is arelol 25mg tablet sr used for?

This medicine is a beta-blocker used to treat high blood pressure, angina, and heart failure. It works by slowing the heart rate and reducing the heart's workload. Take it exactly as prescribed, and do not stop suddenly.

  • Generic Name: Metoprolol Succinate
  • Manufacturer: Aretaeus Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 arelol 25mg tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा मेटोप्रोलोल सक्सिनेट 25 मिलीग्राम युक्त है और उच्च रक्तचाप (हाइपरटेंशन), एनजाइना (सीने में दर्द), और हृदय विफलता के इलाज के लिए उपयोग की जाती है। यह हृदय की गति को धीमा करके और हृदय पर काम का बोझ कम करके काम करती है। इसे डॉक्टर के निर्देशानुसार ही लें और अचानक बंद न करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में थकान, चक्कर आना, हाथ-पैर ठंडे होना, और नींद में गड़बड़ी शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें धीमी हृदय गति, हृदय विफलता का बिगड़ना, और सांस लेने में कठिनाई शामिल हो सकती है। यदि आपको सांस लेने में तकलीफ, पैरों में सूजन, या सीने में दर्द हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे एनजाइना, अनियमित दिल की धड़कन, या दिल का दौरा पड़ सकता है। शराब का सेवन न करें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। यदि आपको अस्थमा, मधुमेह, या लीवर की समस्या है तो डॉक्टर को बताएं। गाड़ी चलाते समय सावधानी बरतें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 arelol 25mg tablet sr Uses & Benefits

[{"condition":"Hypertension","description":"This medicine helps lower high blood pressure by reducing the heart rate and the force of heart contractions, thereby decreasing the workload on the heart and blood vessels.","evidence":"Well-established"},{"condition":"Angina Pectoris","description":"It reduces the frequency and severity of angina attacks by decreasing the heart's oxygen demand, allowing more blood flow to the heart muscle.","evidence":"Well-established"},{"condition":"Heart Failure","description":"Used as part of a treatment regimen to improve survival and reduce hospitalizations in patients with stable heart failure with reduced ejection fraction.","evidence":"Well-established"},{"condition":"Myocardial Infarction (Secondary Prevention)","description":"After a heart attack, this medicine can reduce the risk of another heart attack and improve survival.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine Prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, though it is not FDA-approved for this indication.","evidence":"Limited"},{"condition":"Performance Anxiety","description":"Occasionally used off-label to manage symptoms of performance anxiety, such as rapid heartbeat and tremors.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Angina Pectoris, Heart Failure, Myocardial Infarction

📋 Drug Information

Generic Name(s)Metoprolol Succinate
Brand NameAimet 25mg Tablet XR
ManufacturerAretaeus Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassBeta blocker- Cardioselective
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineThe World Health Organization recommends beta-blockers as one of the first-line classes of antihypertensive medications for patients with compelling indications such as heart failure, ischemic heart disease, and post-myocardial infarction.
ICMR GuidelineThe Indian Council of Medical Research guidelines recommend beta-blockers for the management of hypertension, especially in patients with coexisting coronary artery disease or heart failure.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day, preferably in the morning, to maintain consistent blood levels.
2
Do not stop taking this medicine abruptly; your doctor will gradually reduce the dose to prevent rebound hypertension or angina.
3
Monitor your blood pressure and heart rate regularly and keep a record to share with your doctor.
4
If you have diabetes, be aware that this medicine can mask symptoms of low blood sugar; monitor your glucose levels closely.
5
Avoid alcohol while taking this medicine as it can increase drowsiness and lower blood pressure further.
6
Inform your doctor if you experience persistent dizziness, fatigue, or cold extremities.
7
If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
✅
Chest pain (angina)
This medicine helps reduce angina attacks.
Likely Use
✅
Heart failure
This medicine is used as part of heart failure treatment.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMetoprolol succinate is rapidly and completely absorbed from the gastrointestinal tract after oral administration. However, it undergoes extensive first-pass metabolism in the liver, resulting in a bioavailability of approximately 50%. The extended-release formulation provides a more controlled absorption profile compared to immediate-release formulations.
DistributionMetoprolol is widely distributed throughout the body, including the heart, lungs, liver, and kidneys. It crosses the blood-brain barrier and the placenta. The volume of distribution is approximately 3.2 L/kg.
Protein BindingMetoprolol is approximately 12% bound to plasma proteins, primarily albumin.
MetabolismMetoprolol is extensively metabolized in the liver, primarily by the CYP2D6 enzyme, with minor contributions from CYP3A4. The major metabolic pathway is alpha-hydroxylation, but O-demethylation and N-dealkylation also occur. The metabolites are inactive.
Half-LifeThe elimination half-life of metoprolol is approximately 3 to 7 hours in normal healthy adults. In poor metabolizers (CYP2D6 deficiency), the half-life may be longer.
ExcretionMetoprolol and its metabolites are primarily excreted in the urine. About 95% of an oral dose is excreted in the urine, with less than 5% as unchanged drug.
BioavailabilityThe oral bioavailability of metoprolol succinate is approximately 50% due to first-pass metabolism.
Onset of ActionThe onset of action for blood pressure reduction is within 1 hour after oral administration, but the full therapeutic effect may take several days to weeks.
Peak Plasma TimePeak plasma concentrations are reached approximately 1.5 to 4 hours after oral administration of the extended-release formulation.
Duration of ActionThe duration of action is approximately 24 hours, allowing for once-daily dosing.

How It Works

This medicine works by selectively blocking beta-1 adrenergic receptors located primarily in the heart. By blocking these receptors, it reduces the effects of catecholamines (such as epinephrine and norepinephrine), leading to a decrease in heart rate, contractility, and cardiac output. This results in lower blood pressure and reduced oxygen demand by the heart muscle. Additionally, it suppresses renin release from the kidneys, which contributes to its blood pressure-lowering effect.

Mechanism Steps

1
Selective Beta-1 Blockade: This medicine selectively binds to beta-1 adrenergic receptors in the heart, blocking the action of catecholamines.
2
Reduced Heart Rate and Contractility: Blockade of beta-1 receptors leads to a decrease in heart rate and the force of heart muscle contraction, reducing cardiac output.
3
Decreased Myocardial Oxygen Demand: By slowing the heart and reducing contractility, the heart requires less oxygen, which helps relieve angina.
4
Suppression of Renin Release: Beta-1 blockade in the kidneys reduces renin secretion, leading to decreased angiotensin II and aldosterone levels, which lowers blood pressure.

💡 How to Take arelol 25mg tablet sr

Strength: Metoprolol Succinate 25 mg extended-release tablet

1Take this medicine by mouth with or without food.
2Swallow the tablet whole; do not crush, chew, or break it.
3Take it at the same time each day, preferably in the morning.
4If you have difficulty swallowing, consult your doctor.
5Do not stop taking this medicine suddenly without consulting your doctor.

Dosage Information

Adult DosageThe usual starting dose of this medicine for hypertension is 25 to 50 mg once daily, which may be increased to a maximum of 200 mg once daily based on response. For angina, the typical dose is 100 to 200 mg once daily. For heart failure, the starting dose is 12.5 to 25 mg once daily, gradually titrated to a target dose of 200 mg once daily as tolerated. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced hepatic and renal function and may be more sensitive to the effects of this medicine. Start with a lower dose and titrate slowly. Monitor blood pressure and heart rate closely.
Renal ImpairmentNo dosage adjustment is typically required for mild to moderate renal impairment. In severe renal impairment, monitor closely and adjust dose as needed.
Hepatic ImpairmentIn patients with hepatic impairment, the clearance of metoprolol may be reduced. Start with a lower dose and titrate slowly based on clinical response.
Maximum Daily Dose200 mg per day for hypertension and angina; up to 200 mg per day for heart failure.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with or without food
Food does not significantly affect absorption.
Alcohol
Avoid
May increase drowsiness and low blood pressure.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of arelol 25mg tablet sr

✅ Common Side Effects

Tiredness (Common (10-20%))
Usually resolves with continued use. If persistent, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you. Rise slowly from sitting or lying positions.
Cold Extremities (Common (5-10%))
Keep hands and feet warm. If severe or persistent, consult your doctor.
Slow Heart Rate (Common (5-10%))
Your doctor will monitor your heart rate. Report if it drops below 50 beats per minute or if you feel faint.
Sleep Disturbances (Uncommon (1-5%))
Take the medicine in the morning to reduce sleep disturbances. If persistent, consult your doctor.

🚨 Serious Side Effects

Severe Bradycardia (Rare (<0.1%))
Seek immediate medical attention if you experience a very slow heartbeat, fainting, or severe dizziness.
Worsening Heart Failure (Rare (<0.1%))
Report sudden weight gain, swelling of ankles or feet, or difficulty breathing to your doctor immediately.
Bronchospasm (Rare (<0.1%))
If you have asthma or COPD, seek medical help if you experience wheezing or difficulty breathing.
Severe Allergic Reaction (Very Rare (<0.01%))
Seek emergency care if you develop rash, itching, swelling of the face, lips, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Depression
Consult your doctor if you experience persistent sadness or loss of interest in activities.
Hallucinations
Seek immediate medical attention if you experience hallucinations.
Thrombocytopenia
Report unusual bruising or bleeding to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Verapamil Major
Diltiazem Major
Clonidine Major
MAOIs Major
NSAIDs Moderate
Fluoxetine Moderate
Paroxetine Moderate
Insulin Moderate
Antacids Minor
Cimetidine Minor

🚨 Major Interactions

  • Verapamil
  • Diltiazem
  • Clonidine
  • Monoamine Oxidase Inhibitors (MAOIs)

⚡ Moderate Interactions

  • NSAIDs
  • CYP2D6 Inhibitors (e.g., fluoxetine, paroxetine)
  • Insulin and Oral Hypoglycemics

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering and sedative effects of this medicine, leading to dizziness, fainting, and increased risk of falls. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe bradycardia","Second or third-degree heart block","Cardiogenic shock","Decompensated heart failure","Sick sinus syndrome","Severe peripheral arterial circulatory disorders","Hypersensitivity to metoprolol or any component of the formulation"]

⚠️ Warnings & Precautions

["Do not abruptly discontinue this medicine; taper gradually to avoid exacerbation of angina, myocardial infarction, or ventricular arrhythmias.","Use with caution in patients with bronchospastic diseases (e.g., asthma, COPD); may cause bronchospasm.","May mask symptoms of hypoglycemia in diabetic patients; monitor blood glucose closely.","May mask symptoms of hyperthyroidism; abrupt withdrawal may precipitate thyroid storm.","Use with caution in patients with peripheral vascular disease; may worsen symptoms of arterial insufficiency.","May cause dizziness or fatigue; avoid driving or operating machinery until effects are known.","Use with caution in patients with hepatic impairment; dose adjustment may be needed.","May increase the risk of depression; monitor mood changes."]

🤱 Lactation Safety

Metoprolol is excreted in human breast milk in small amounts. The amount ingested by the infant is generally considered safe, but monitor the infant for signs of beta-blockade such as bradycardia, hypotension, and poor feeding. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose of this medicine can cause severe bradycardia, hypotension, heart failure, bronchospasm, and hypoglycemia. Treatment is supportive and symptomatic. If overdose is suspected, seek emergency medical attention immediately. Management may include gastric lavage, activated charcoal, atropine for bradycardia, vasopressors for hypotension, and glucagon. Hemodialysis is not effective in removing metoprolol.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not stop taking it suddenly, as this can worsen your condition or cause chest pain, irregular heartbeat, or a heart attack. If you need to stop, your doctor will gradually reduce your dose. Avoid drinking alcohol while taking this medicine, as it can increase drowsiness and lower your blood pressure further. Inform your doctor if you have asthma, diabetes, or liver problems. This medicine may cause dizziness; avoid driving or operating heavy machinery until you know how it affects you. Keep all appointments with your doctor and have your blood pressure and heart rate checked regularly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of this medicine, particularly bradycardia and hypotension. Start with a lower dose and titrate slowly. Monitor renal and hepatic function regularly.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before conception. This medicine is Pregnancy Category C and may not be the first choice during pregnancy. Your doctor may switch you to a safer alternative.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect heart rate and blood pressure during surgery. Do not stop the medicine unless instructed by your doctor.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine, as it may interact with certain local anesthetics containing epinephrine. Your dentist may need to adjust the anesthetic used.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight through balanced diet and regular exercise.
🥗
Limit salt intake to help control blood pressure.
😴
Avoid smoking and excessive alcohol consumption.
💧
Manage stress through relaxation techniques like yoga or meditation.
🧘
Get adequate sleep and follow a regular sleep schedule.
🌞
Monitor your blood pressure at home and keep a log.

🏋️ Exercise Considerations

This medicine may cause dizziness or fatigue, especially when starting treatment or increasing the dose. Avoid strenuous exercise until you know how it affects you. Stay hydrated during exercise. If you experience chest pain, shortness of breath, or severe dizziness during exercise, stop and seek medical attention.

🥗 Diet Recommendations

Follow a heart-healthy diet rich in fruits, vegetables, and whole grains.
Reduce sodium intake to less than 2,300 mg per day.
Limit saturated and trans fats.
Include potassium-rich foods like bananas and oranges, unless advised otherwise.
Avoid excessive caffeine.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tiredness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It should not affect your ability to work in most other settings, but inform your employer if your job involves heavy machinery or driving.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Abrupt discontinuation can worsen angina, cause heart attack, or lead to serious heart rhythm problems. Your doctor will gradually reduce the dose if discontinuation is necessary.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe and effective for managing chronic cardiovascular conditions. Regular monitoring of blood pressure, heart rate, and renal function is recommended. It may reduce the risk of heart attack and stroke in high-risk patients. Do not stop without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can help manage blood pressure and heart health.

Evidence: Well-established
Other antihypertensive classes

ACE inhibitors, ARBs, calcium channel blockers, or diuretics may be alternatives.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine, especially if you have underlying health conditions.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. If crossing time zones, adjust the timing of your dose gradually to maintain a 24-hour interval. Store it in a cool, dry place away from direct sunlight. Check customs regulations for carrying prescription medications. Always carry enough supply for your entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with high blood pressure and angina
He was prescribed this medicine 25 mg once daily. Initially, he felt tired and dizzy, but these effects subsided after a week. His blood pressure normalized, and angina attacks became less frequent. He emphasizes the importance of taking it at the same time every day and not skipping doses.
💡 Lesson: Consistency and patience are key; side effects often diminish with continued use.
👤 A 62-year-old woman with heart failure
She started on a low dose of this medicine and gradually increased it under her doctor's supervision. She experienced mild fatigue but noticed improved breathing and reduced swelling in her legs. She advises others to follow the titration schedule strictly and report any worsening symptoms.
💡 Lesson: Gradual dose titration improves tolerability and outcomes in heart failure.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 1 hour, but the full effect may take several days to weeks.

Q: Can I stop taking this medicine if I feel better?

A: No, do not stop suddenly. Consult your doctor before making any changes.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember if less than 12 hours have passed. Otherwise, skip it and continue with your regular schedule.

Q: Is it safe to take during pregnancy?

A: It is Pregnancy Category C. Consult your doctor to weigh benefits and risks.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for arelol 25mg tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: This medicine controls blood pressure but does not cure it. Stopping suddenly can cause serious heart problems. Continue as prescribed.
  • Myth: This medicine causes weight gain.
    Fact: Weight gain is not a common side effect of this medicine. However, if you experience rapid weight gain, it may indicate fluid retention and should be reported to your doctor.
  • Myth: This medicine is addictive.
    Fact: This medicine is not addictive. It is a prescription medication for cardiovascular conditions.

🔄 Alternative Options

Generic Alternatives

  • Metoprolol Succinate 25 mg extended-release tablet

Brand Alternatives

  • Aimet 25mg Tablet XR

📊 Comparison with Similar Medicines

[{"medicine":"Metoprolol Succinate","class":"Beta-1 selective blocker","half_life":"3-7 hours","frequency":"Once daily"},{"medicine":"Atenolol","class":"Beta-1 selective blocker","half_life":"6-7 hours","frequency":"Once or twice daily"},{"medicine":"Bisoprolol","class":"Beta-1 selective blocker","half_life":"10-12 hours","frequency":"Once daily"},{"medicine":"Carvedilol","class":"Non-selective beta and alpha blocker","half_life":"7-10 hours","frequency":"Twice daily"}]

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