Bploc R 25mg/2.5mg Tablet: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or wheezing
- Severe dizziness or fainting
- Chest pain or irregular heartbeat
- Decreased urine output or swelling in the legs
- Yellowing of the skin or eyes
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is davaindia metoprolol succinate+ramipril 25mg/2.5mg tablet used for?
This medicine is a combination of Metoprolol Succinate and Ramipril used to treat high blood pressure and certain heart conditions. It works by slowing the heart rate and relaxing blood vessels. It must be taken exactly as prescribed and should not be stopped abruptly.
- Generic Name: Metoprolol Succinate + Ramipril
- Manufacturer: Davaindia Generic Pharmacy
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 davaindia metoprolol succinate+ramipril 25mg/2.5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मेटोप्रोलोल सक्सिनेट और रामिप्रिल का संयोजन है, जिसका उपयोग उच्च रक्तचाप (हाइपरटेंशन) और कुछ हृदय रोगों के इलाज के लिए किया जाता है। यह हृदय की गति को धीमा करती है और रक्त वाहिकाओं को आराम देती है, जिससे रक्तचाप कम होता है। यह दवा दिल के दौरे के बाद और हृदय विफलता में भी लाभकारी है। इसे डॉक्टर के निर्देशानुसार ही लें, अपने आप बंद न करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में थकान, चक्कर आना, सिरदर्द, धीमी हृदय गति, और पेट की गड़बड़ी शामिल हैं। कुछ रोगियों में सूखी खांसी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन चेहरे, होंठ, जीभ या गले में सूजन, सांस लेने में कठिनाई, या बेहोशी होने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे एनजाइना या दिल का दौरा पड़ सकता है। नियमित रूप से अपना रक्तचाप और हृदय गति जांचते रहें। शराब से बचें। गर्भावस्था के दौरान इस दवा का सेवन न करें। पोटेशियम सप्लीमेंट या नमक के विकल्प बिना डॉक्टर की सलाह के न लें। नियमित जांच के लिए डॉक्टर के पास जाएं।
💊 davaindia metoprolol succinate+ramipril 25mg/2.5mg tablet Uses & Benefits
[{"condition":"Hypertension","description":"Used to lower blood pressure in adults when combination therapy is appropriate, reducing the risk of stroke, heart attack, and kidney damage.","evidence":"Well-established"},{"condition":"Heart failure with reduced ejection fraction","description":"Helps improve survival and reduce hospitalizations by slowing heart rate and reducing cardiac workload.","evidence":"Well-established"},{"condition":"Post-myocardial infarction","description":"Prescribed after a heart attack to reduce the risk of reinfarction and improve survival.","evidence":"Well-established"},{"condition":"Diabetic nephropathy","description":"Ramipril component helps slow kidney damage in patients with diabetes and hypertension.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label for preventing migraines, though evidence is limited.","evidence":"Limited"},{"condition":"Anxiety with palpitations","description":"Beta-blocker component may be used off-label for performance anxiety with physical symptoms.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Heart failure, Post-myocardial infarction, Diabetic nephropathy
📋 Drug Information
| Generic Name(s) | Metoprolol Succinate + Ramipril |
| Brand Name | Ace Revelol 50/5 Tablet ER |
| Manufacturer | Davaindia Generic Pharmacy |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Beta-blocker + ACE inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization recommends ACE inhibitors or beta-blockers as first-line agents for hypertension in certain patient populations, but combination therapy should be individualized. Not established from the available information for this specific combination. |
| ICMR Guideline | The Indian Council of Medical Research guidelines recommend individualized therapy for hypertension, with combination therapy considered when monotherapy fails. Not established from the available information for this specific combination. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Metoprolol Succinate selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, contractility, and cardiac output. Ramipril inhibits the angiotensin-converting enzyme, preventing the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This leads to vasodilation, reduced aldosterone secretion, and decreased sodium and water retention. Together, they lower blood pressure and reduce myocardial oxygen demand.
Mechanism Steps
💡 How to Take davaindia metoprolol succinate+ramipril 25mg/2.5mg tablet
Strength: Each tablet contains Metoprolol Succinate 25 mg and Ramipril 2.5 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once or twice daily, depending on the individual's condition and response. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and concomitant medications. Do not self-adjust the dose. Regular monitoring of blood pressure, heart rate, and kidney function is required. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially dizziness and hypotension. Start with a low dose and titrate slowly. Monitor renal function and electrolytes regularly. |
| Renal Impairment | Dose adjustment may be required in patients with renal impairment. Ramipril is primarily excreted by the kidneys. In severe renal impairment (eGFR <30 mL/min), the dose should be reduced or alternative therapy considered. Consult a nephrologist. |
| Hepatic Impairment | Metoprolol is metabolized in the liver. In patients with hepatic impairment, the dose should be reduced and monitored closely. Ramipril may also require dose adjustment. Consult a hepatologist. |
| Maximum Daily Dose | The maximum daily dose should not exceed the prescribed amount. For this combination, the maximum recommended dose is typically one tablet twice daily, but this must be determined by a clinician based on individual patient factors. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of davaindia metoprolol succinate+ramipril 25mg/2.5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Spironolactone | Major | |
| Ibuprofen | Major | |
| Verapamil | Major | |
| Clonidine | Major | |
| Lithium | Major | |
| Fluoxetine | Moderate | |
| Prazosin | Moderate | |
| Insulin | Moderate | |
| Antacids | Minor | |
| Cimetidine | Minor |
🚨 Major Interactions
- Potassium-sparing diuretics (e.g., spironolactone)
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Verapamil or diltiazem
- Clonidine
- Lithium
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
- Alpha-blockers (e.g., prazosin)
- Insulin and oral hypoglycemics
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effects of this medicine, leading to dizziness, lightheadedness, and fainting. It is advisable to avoid alcohol or limit intake significantly while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Asthma or severe chronic obstructive pulmonary disease","Severe bradycardia or heart block (second or third degree)","Cardiogenic shock or decompensated heart failure","History of angioedema related to ACE inhibitors","Bilateral renal artery stenosis","Pregnancy","Concurrent use with aliskiren in patients with diabetes"]
⚠️ Warnings & Precautions
["Do not stop abruptly, as it may worsen angina or precipitate myocardial infarction.","May mask symptoms of hypoglycemia in diabetic patients.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid potassium supplements and salt substitutes containing potassium.","Inform your doctor if you have a history of psoriasis, as beta-blockers may worsen it.","Use with caution in patients with peripheral vascular disease or Raynaud's phenomenon."]
🤱 Lactation Safety
Metoprolol is excreted in breast milk in small amounts and may cause bradycardia in the infant. Ramipril is also excreted in breast milk. The combination is not recommended during breastfeeding. Consult your doctor for alternative options.
💊 Overdose Management
Overdose can cause severe bradycardia, hypotension, heart failure, bronchospasm, and renal failure. Treatment is supportive and symptomatic. Atropine may be used for bradycardia. Glucagon can be used for beta-blocker toxicity. Hemodialysis may be considered for ramipril removal. Seek immediate medical attention.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not stop or change the dose without medical advice, as abrupt withdrawal of Metoprolol Succinate can worsen angina or precipitate a heart attack. Monitor your blood pressure and heart rate regularly, especially when starting or adjusting the dose. Avoid alcohol, as it can enhance the blood pressure-lowering effect and cause dizziness. Inform your doctor if you have asthma, diabetes, kidney disease, liver disease, or a history of angioedema. Do not use potassium supplements or salt substitutes containing potassium without consulting your doctor. If you become pregnant or plan to become pregnant, contact your doctor immediately, as this medicine can harm the fetus. Keep all follow-up appointments for blood tests, including kidney function and potassium levels.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the blood pressure-lowering and heart rate-slowing effects of this medicine. Start with a low dose and titrate slowly. Monitor renal function and electrolytes regularly. Falls risk may be increased due to dizziness.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception. Use effective contraception while taking this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine, as it can interact with anesthetic agents and affect heart rate and blood pressure during surgery. Do not stop the medicine without your doctor's advice.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may cause dry mouth or interact with local anesthetics containing epinephrine. Your dentist may need to adjust the anesthetic used.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or fatigue, especially when starting treatment. Avoid strenuous exercise until you know how it affects you. Stay hydrated and rise slowly from sitting or lying positions to prevent dizziness.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is important to take the medicine at the same time each day, which may require adjusting your work schedule.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Abrupt withdrawal can cause rebound hypertension, angina, or heart attack. Your doctor may gradually reduce the dose if needed.
📅 Long-Term Use Effects
Long-term use of this medicine requires regular monitoring of blood pressure, heart rate, kidney function, and electrolytes. It can effectively control blood pressure and reduce cardiovascular risk, but may cause persistent dry cough, fatigue, or sexual dysfunction. Regular follow-up is essential to adjust the dose and manage any side effects.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress reduction can complement medicine for blood pressure control.
Evidence: Well-establishedDepending on individual needs, other combinations like ARBs with calcium channel blockers may be considered.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, consult your doctor before receiving any live vaccines, as your immune response may be affected by underlying conditions.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, adjust dosing times gradually in consultation with your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within 1-2 hours, but full therapeutic effect may take several weeks. Regular monitoring is important.
A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, do not stop this medicine abruptly without consulting your doctor, as it can worsen heart conditions.
A: No, this medicine is not recommended during pregnancy as it can harm the fetus. Consult your doctor for alternative options.
🤔 Common Patient Concerns
🔄 Substitutes for davaindia metoprolol succinate+ramipril 25mg/2.5mg tablet
View AllAlternative brands with exact same active ingredient:
-
ramidace-m 25 tablet erCare Formulation Labs Pvt Ltd ₹42.19 155.7% COSTLIER
-
metolet r 25mg/2.5mg tabletIkon Remedies Pvt Ltd ₹65.16 294.9% COSTLIER
-
metopole-rm tabletKnoll Pharmaceuticals Ltd ₹73.13 343.2% COSTLIER
-
roforil-m 2.5/25mg tablet erRiyadh Pharmaceutical ₹76.00 360.6% COSTLIER
-
metpol-r 25mg/2.5mg tablet xlOctane Biotech Pvt Ltd ₹84.38 411.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often requires lifelong treatment. Stopping suddenly can cause dangerous rebound hypertension or heart problems. - Myth: This medicine causes kidney damage.
Fact: When used appropriately and monitored, this medicine can protect the kidneys, especially in diabetics. Regular monitoring is essential. - Myth: You can drink alcohol while taking this medicine.
Fact: Alcohol can enhance the blood pressure-lowering effect and cause dizziness or fainting. It is best avoided.
🔄 Alternative Options
Generic Alternatives
- Metoprolol Succinate + Ramipril (generic versions available)