aqukof-dx syrup sugar free - Phenylephrine (5mg) + Chlorpheniramine Maleate (2mg) medicine

aqukof-dx syrup sugar free - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Aquver Pharma Private Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is aqukof-dx syrup sugar free used for?

Ascoril D Plus Syrup Sugar Free (Phenylephrine + Chlorpheniramine Maleate) is used to treat RESPIRATORY. It contains Phenylephrine (5mg) + Chlorpheniramine Maleate (2mg), which Phenylephrine: alpha-1 adrenergic agonist causing vasoconstriction; Chlorphenira. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Phenylephrine + Chlorpheniramine Maleate
  • Manufacturer: Aquver Pharma Private Limited
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š aqukof-dx syrup sugar free Uses & Benefits

Allergic rhinitis, Common cold, Sinusitis

๐Ÿ“‹ Drug Information

Generic Name(s)Phenylephrine + Chlorpheniramine Maleate
Brand NameAscoril D Plus Syrup Sugar Free
ManufacturerAquver Pharma Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassDecongestant + Antihistamine
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from gastrointestinal tract
DistributionDistributes widely; crosses blood-brain barrier
Protein BindingPhenylephrine: low; Chlorpheniramine: 70%
MetabolismPhenylephrine: hepatic (MAO); Chlorpheniramine: hepatic (CYP450)
Half-LifePhenylephrine: 2-3 hours; Chlorpheniramine: 12-15 hours
ExcretionRenal (urine)
BioavailabilityPhenylephrine: ~38%; Chlorpheniramine: ~25-50%
Onset of ActionPhenylephrine: 15-30 min; Chlorpheniramine: 30-60 min
Peak Plasma TimePhenylephrine: 1-2 hours; Chlorpheniramine: 2-6 hours
Duration of ActionPhenylephrine: 4-6 hours; Chlorpheniramine: 4-6 hours

How It Works

Phenylephrine: alpha-1 adrenergic agonist causing vasoconstriction; Chlorpheniramine: H1 receptor antagonist blocking histamine effects

Mechanism Steps

1Phenylephrine binds to alpha-1 adrenergic receptors on vascular smooth muscle
2Causes vasoconstriction in nasal mucosa, reducing congestion
3Chlorpheniramine blocks H1 receptors on blood vessels and respiratory epithelium

๐Ÿ’ก How to Take aqukof-dx syrup sugar free

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of aqukof-dx syrup sugar free

โœ… Common Side Effects

  • Drowsiness
  • Dry mouth
  • Nausea
  • Dizziness
  • Headache

๐Ÿšจ Serious Side Effects

  • Hypertension
  • Arrhythmias
  • Seizures
  • Urinary retention

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Thrombocytopenia
  • Hallucinations

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

๐Ÿšจ Major Interactions

  • MAOIs
  • Beta-blockers
  • Tricyclic antidepressants

โšก Moderate Interactions

  • Antihypertensives
  • Sympathomimetics
  • CNS depressants

โ„น๏ธ Minor Interactions

  • Antacids
  • Caffeine

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase chlorpheniramine levels

๐Ÿท Alcohol Interaction

Increased CNS depression

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypertension, Hyperthyroidism, Diabetes, Glaucoma, MAOI use, Severe coronary artery disease

๐Ÿ“Š Monitoring Parameters

Blood pressure, Heart rate, CNS effects

๐Ÿคฑ Lactation Safety

Caution; may be excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; may include activated charcoal, benzodiazepines for seizures

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

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