aqueous ultra eye drop - Polyethylene Glycol (0.4% w/v) + Propylene Glycol (0.3% w/v) medicine

Appe Eye Drop: Complete Guide to Uses, Side Effects, and Safety

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🏭 Optho Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for dry eye symptom relief.
Reviewed by
SaathiMed Expert Panel | Sep 22, 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden loss of vision or severe eye pain
  • Severe headache with nausea or vomiting
  • Increased redness, swelling, or discharge from the eye
  • Swelling of the face, lips, or throat, or difficulty breathing
  • Eye pain or discomfort that does not improve with use
  • Flashes of light or floaters in the vision
  • Persistent blurred vision after using the drops

If experiencing severe symptoms, call emergency services immediately.

What is aqueous ultra eye drop used for?

This medicine is an artificial tear solution containing polyethylene glycol 0.4% and propylene glycol 0.3%. It lubricates the eyes and relieves dryness, burning, and irritation. It is used for dry eye syndrome and can be applied as needed, usually 3-4 times a day.

  • Generic Name: Polyethylene Glycol + Propylene Glycol
  • Manufacturer: Optho Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 aqueous ultra eye drop के बारे में (Hindi Summary)

उपयोग: यह दवा आंखों की सूखापन, जलन, और असुविधा को दूर करने के लिए इस्तेमाल की जाती है। यह कृत्रिम आंसू के रूप में काम करती है और आंखों की सतह को नमी प्रदान करती है। यह ड्राई आई सिंड्रोम, कंप्यूटर विजन सिंड्रोम, और आंखों की सर्जरी के बाद होने वाली सूखापन के लिए उपयोगी है। यह दवा आंखों में एक सुरक्षात्मक परत बनाती है जिससे पलक झपकने पर होने वाली रगड़ कम होती है। यह दवा आमतौर पर वयस्कों और बच्चों दोनों के लिए सुरक्षित है, लेकिन उपयोग से पहले डॉक्टर से सलाह लें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में अस्थायी धुंधली दृष्टि, हल्की जलन या चुभन, और आंख में कुछ महसूस होना शामिल है। ये प्रभाव आमतौर पर कुछ मिनटों में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको गंभीर एलर्जी, आंख में तेज दर्द, या दृष्टि में बदलाव महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले और बाद में अपने हाथ धोएं। ड्रॉपर की टिप को आंख या किसी सतह से न छुएं। यदि आप कॉन्टैक्ट लेंस पहनते हैं, तो दवा डालने से पहले उन्हें निकाल लें और 15 मिनट बाद ही दोबारा पहनें। दवा की बोतल को खोलने के 30 दिन बाद उसका उपयोग न करें। यदि लक्षण 7 दिनों से अधिक बने रहें, तो डॉक्टर से सलाह लें। इस दवा को बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 aqueous ultra eye drop Uses & Benefits

[{"condition":"Dry eye syndrome (keratoconjunctivitis sicca)","description":"Relieves dryness, burning, and irritation by supplementing natural tears and stabilizing the tear film.","evidence":"Well-established"},{"condition":"Ocular surface protection after surgery","description":"Used post-operatively to lubricate the eye and promote healing after procedures such as LASIK or cataract surgery.","evidence":"Well-established"},{"condition":"Exposure keratitis","description":"Provides moisture when the eyelids cannot close completely, preventing corneal damage.","evidence":"Well-established"},{"condition":"Computer vision syndrome","description":"Reduces eye strain and dryness associated with prolonged screen use.","evidence":"Well-established"},{"condition":"Medication-induced dry eye","description":"Helps manage dryness caused by medications such as antihistamines, antidepressants, or diuretics.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Contact lens discomfort","description":"Sometimes used to lubricate eyes before inserting contact lenses to reduce discomfort.","evidence":"Limited"},{"condition":"Allergic conjunctivitis","description":"May provide temporary relief from irritation, but does not treat the underlying allergy.","evidence":"Limited"}]

Primary treatment for: Dry eye syndrome

Also treats: Computer vision syndrome, Exposure keratitis, Post-operative ocular dryness, Medication-induced dry eye

📋 Drug Information

Generic Name(s)Polyethylene Glycol + Propylene Glycol
Brand NameAppe Eye Drop
ManufacturerOptho Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassOcular Lubricant
Route of AdministrationOphthalmic (topical eye drop)
StorageStore at room temperature (15-30°C). Protect from light and moisture. Keep the bottle tightly closed when not in use. Do not freeze.
Shelf Life24 months from the date of manufacture. Discard 30 days after opening the bottle.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Use this medicine as needed, but if you find yourself using it more than 4 times a day, consult your eye doctor to rule out other causes of dry eye.
2
Always wash your hands before instilling the drops to prevent contamination and eye infections.
3
If you use other eye drops, wait at least 5 minutes between applications to avoid washing out the previous medicine.
4
Store the bottle in a cool, dry place and never use it beyond 30 days after opening.
5
If you wear contact lenses, remove them before using this medicine and wait 15 minutes before reinserting.
6
Do not share your eye drops with anyone else, as this can spread infections.
7
If your symptoms do not improve within 7 days, or if they worsen, seek professional eye care.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Dryness in eyes
This medicine is commonly used for this symptom.
Likely Use
Burning sensation in eyes
This medicine can provide relief.
Likely Use
Eye infection with discharge
This medicine is not an antibiotic and should not be used for infections.
Not Primary
Eye pain with vision loss
This medicine is not for emergency eye conditions. Seek immediate medical help.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSystemic absorption is negligible because this medicine is applied topically to the eye and the active ingredients are large polymers that do not readily cross the corneal barrier. Any small amount that drains into the nasolacrimal duct is swallowed and excreted without significant systemic uptake.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionRelief from dryness and irritation is typically felt within a few minutes after instillation.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe lubricating effect usually lasts for 1 to 2 hours, depending on individual tear production and environmental factors.

How It Works

This medicine works by forming a protective, lubricating film over the cornea and conjunctiva. Polyethylene glycol and propylene glycol are hygroscopic polymers that attract and retain water molecules, thereby increasing the thickness and stability of the tear film. They reduce friction between the eyelids and the ocular surface during blinking, which helps prevent epithelial damage. Additionally, they help restore the natural balance of the tear film's lipid, aqueous, and mucin layers, providing symptomatic relief from dryness and irritation.

Mechanism Steps

1
Instillation and spread: Upon instillation, the solution spreads evenly across the ocular surface, coating the cornea and conjunctiva.
2
Water retention: Polyethylene glycol and propylene glycol attract and bind water molecules, creating a hydrated layer that mimics natural tears.
3
Tear film stabilization: The hydrated polymers integrate into the tear film, enhancing its stability and reducing evaporation.
4
Friction reduction: The lubricating layer minimizes friction between the eyelids and the eye surface during blinking, preventing microtrauma.
5
Symptom relief: This results in reduced dryness, burning, and irritation, improving overall eye comfort.

💡 How to Take aqueous ultra eye drop

Strength: Polyethylene Glycol 0.4% w/v + Propylene Glycol 0.3% w/v ophthalmic solution

1Wash your hands thoroughly with soap and water.
2Shake the bottle gently if instructed on the label.
3Tilt your head back and look up.
4Pull down your lower eyelid to form a small pocket.
5Hold the dropper above the eye and squeeze one drop into the pocket.
6Close your eye gently for 1-2 minutes without blinking or squinting.
7Press a finger gently against the inner corner of your eye near the nose to prevent the drop from draining into your throat.
8Repeat in the other eye if needed.
9Replace the cap tightly after use.

Dosage Information

Adult DosageThe usual adult dose is one drop in the affected eye(s) as needed, typically 3 to 4 times daily, or as directed by your eye care professional. For severe dryness, more frequent use may be recommended. Dose must be individualized by a qualified clinician based on the severity of symptoms, underlying cause, and response to treatment. Do not exceed the recommended frequency without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician or eye specialist for appropriate use in children.
Elderly DosageNo specific dosage adjustment is required for elderly patients. However, elderly individuals may have reduced tear production and may need more frequent use. Consult a doctor for personalized advice.
Renal ImpairmentNo dosage adjustment is required for patients with renal impairment because systemic absorption is negligible.
Hepatic ImpairmentNo dosage adjustment is required for patients with hepatic impairment because systemic absorption is negligible.
Maximum Daily DoseThere is no established maximum daily dose for this medicine. Use as needed, but do not exceed the frequency recommended by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of aqueous ultra eye drop

✅ Common Side Effects

Temporary blurred vision (Common (5-10%))
Wait a few minutes until vision clears before driving or operating machinery.
Mild stinging or burning (Common (5-10%))
Usually resolves within minutes. If persistent, consult your doctor.
Foreign body sensation (Common (5-10%))
This sensation typically subsides as the solution spreads. If it continues, consult your eye care professional.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, throat, or difficulty breathing.
Eye infection (Rare (<0.1%))
Consult a doctor if you notice increased redness, pain, or discharge from the eye.
Corneal damage (Rare (<0.1%))
Discontinue use and seek ophthalmological care if you experience severe eye pain or vision loss.

⚠️ Rare Side Effects

Ocular hypersensitivity
Stop using the medicine and consult your doctor if you develop itching, redness, or swelling.
Punctate keratitis
Report to your eye specialist if you experience persistent eye pain or light sensitivity.

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to polyethylene glycol, propylene glycol, or any other ingredient in this medicine.","Active eye infection (bacterial, viral, or fungal) unless prescribed by a doctor.","Use in children under 2 years of age unless directed by a pediatrician."]

⚠️ Warnings & Precautions

["Do not touch the dropper tip to any surface to avoid contamination.","If you experience eye pain, headache, vision changes, or persistent redness, stop use and consult a doctor.","Do not use this medicine if the solution is cloudy or discolored.","Remove contact lenses before use and wait 15 minutes before reinserting.","Do not use this medicine after the expiry date.","Keep out of reach of children.","If symptoms worsen or persist for more than 7 days, consult an eye specialist.","Do not use this medicine while wearing contact lenses unless advised by your doctor."]

🤱 Lactation Safety

It is not known whether this medicine passes into breast milk. Since systemic absorption is negligible, it is unlikely to affect a nursing infant. However, consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely due to its topical route. If accidental ingestion occurs, drink plenty of water and seek medical advice. If excessive eye instillation occurs, rinse the eye with clean water and consult a doctor if irritation persists.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Wash your hands thoroughly before and after using this medicine. Do not touch the tip of the dropper to your eye, eyelid, or any surface to avoid contamination. If you wear contact lenses, remove them before instilling this medicine and wait at least 15 minutes before reinserting them, unless your doctor advises otherwise. Do not use this medicine if the solution changes color or becomes cloudy. Do not share this medicine with anyone else. If you are pregnant or breastfeeding, consult your doctor before using this medicine. If you have a history of eye infections, glaucoma, or any other eye condition, inform your doctor before use. Do not use this medicine for more than 30 days after opening the bottle, as it may become contaminated. If symptoms persist or worsen after 7 days of use, stop using this medicine and consult an eye specialist. Keep this medicine out of the reach of children. Do not use this medicine after the expiry date printed on the label.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced tear production and may need more frequent use of this medicine. No dosage adjustment is required, but regular eye check-ups are recommended.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Although systemic absorption is negligible, it is best to seek medical advice.

🏥 Post-Surgery Considerations

This medicine is often prescribed after eye surgery to keep the eye lubricated and promote healing. Use as directed by your surgeon. Do not touch the eye or the dropper tip to the surgical area.

🦷 Dental Procedures

No specific considerations for dental procedures. You can continue using this medicine as usual.

💚 Lifestyle Tips for Better Results

🏃
Follow the 20-20-20 rule: every 20 minutes, look at something 20 feet away for 20 seconds.
🥗
Use a humidifier in dry environments to keep the air moist.
😴
Wear sunglasses outdoors to protect your eyes from wind and sun.
💧
Stay hydrated by drinking plenty of water throughout the day.
🧘
Avoid smoking and secondhand smoke, which can worsen dry eyes.
🌞
Include omega-3 fatty acids in your diet, as they may support tear production.
🚭
Blink frequently, especially when using digital devices.

🏋️ Exercise Considerations

No specific exercise restrictions while using this medicine. However, if you experience blurred vision after instillation, avoid activities that require clear vision until it resolves.

🥗 Diet Recommendations

Include foods rich in omega-3 fatty acids, such as salmon, flaxseeds, and walnuts.
Eat plenty of fruits and vegetables rich in vitamins A, C, and E.
Reduce intake of processed foods and sugary drinks.
Stay well hydrated by drinking at least 8 glasses of water a day.

💼 Impact on Daily Work & Life

This medicine may cause temporary blurred vision immediately after use. It is advisable to wait until your vision clears before driving or operating heavy machinery. Otherwise, it does not affect your ability to work or perform daily activities. You can use it at work as needed, but ensure you wash your hands before application.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if your symptoms worsen, if you develop eye pain, redness, or swelling, or if you experience an allergic reaction. Do not stop using prescribed eye drops without consulting your doctor, especially if you have an underlying eye condition.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe and does not cause systemic side effects. However, prolonged use may lead to dependence on artificial tears, and in rare cases, sensitivity to the ingredients may develop. It is important to have regular eye check-ups if you use this medicine daily for more than a few weeks. If your symptoms persist, your doctor may investigate underlying conditions such as blepharitis or autoimmune diseases.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Warm compresses

Applying a warm compress to the eyes can help unblock oil glands and improve tear quality.

Evidence: Well-established
Omega-3 supplements

May help reduce inflammation and improve dry eye symptoms.

Evidence: Moderate
Punctal plugs

Tiny plugs inserted into tear ducts to reduce tear drainage, often used for severe dry eye.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction between this medicine and vaccines. You can receive vaccinations while using this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Discard 30 days after opening

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

When traveling, carry this medicine in your hand luggage to avoid extreme temperatures. Keep it in its original packaging with the prescription label. If traveling internationally, carry a copy of your prescription to avoid customs issues. Store at room temperature and avoid direct sunlight. If you are flying, the drop in cabin pressure may cause the bottle to leak slightly; keep it in a sealed plastic bag. Do not use the drops if they become cloudy or discolored. If you are traveling to a dry climate, you may need to use the drops more frequently.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old software engineer who spends 10 hours a day in front of a computer.
He experienced constant eye dryness, burning, and redness. His ophthalmologist recommended this medicine. He started using one drop in each eye three times a day. Within a week, his symptoms improved significantly. He also started following the 20-20-20 rule (every 20 minutes, look 20 feet away for 20 seconds).
💡 Lesson: Regular use of this medicine along with lifestyle modifications can greatly improve computer-related dry eye.
👤 A 60-year-old woman who had cataract surgery and developed dry eye post-operatively.
After surgery, she felt a gritty sensation and blurred vision. Her doctor prescribed this medicine to be used four times a day. She noticed relief within two days. She continued use for a month and her symptoms resolved completely.
💡 Lesson: This medicine is effective for post-surgical dry eye and should be used as directed to promote healing.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine provides relief within a few minutes after instillation. The effect lasts for 1-2 hours.

Q: Can I use this medicine with other eye drops?

A: Yes, but wait at least 5 minutes between different eye drops to prevent washing out the previous medicine.

Q: Is this medicine safe for long-term use?

A: Yes, it is safe for long-term use as directed. However, if you need it more than 4 times a day, consult your doctor.

Q: What should I do if I miss a dose?

A: Apply the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule.

Q: Can I use this medicine if I have an eye infection?

A: No, this medicine is not for eye infections. Consult a doctor if you have an infection.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine every day?
  • Will it affect my vision in the long term?
  • Can I drive after using this medicine?
  • Does it interact with other eye drops?
  • What if I miss a dose?
  • Can I use it with contact lenses?
  • Is it safe during pregnancy?
  • How long can I use it continuously?

🔄 Substitutes for aqueous ultra eye drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure dry eye permanently.
    Fact: This medicine provides temporary relief but does not cure the underlying cause of dry eye.
  • Myth: Using this medicine frequently is harmful.
    Fact: When used as directed, this medicine is safe for frequent use. However, consult your doctor if you need it more than 4 times a day.
  • Myth: This medicine can be used for eye infections.
    Fact: This medicine is not an antibiotic or antiviral. It should not be used to treat eye infections.

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredient":"Polyethylene glycol 0.4% + Propylene glycol 0.3%","primary_use":"Dry eye syndrome","preservative":"Preservative-free","contact_lens_compatible":"Remove before use, reinsert after 15 minutes"},{"medicine":"Carboxymethylcellulose sodium 0.5%","active_ingredient":"Carboxymethylcellulose sodium","primary_use":"Dry eye syndrome","preservative":"May contain preservative","contact_lens_compatible":"Remove before use, reinsert after 15 minutes"}]

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