allercool eye drop - Naphazoline (0.05% w/v) + Chlorpheniramine Maleate (0.1% w/v) medicine

Allercool Eye Drop: Complete Guide to Uses, Dosage, and Safety

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🏭 Optho Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for allergic conjunctivitis.
Reviewed by
SaathiMed Expert Panel | Sep 22, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe eye pain or headache
  • Sudden vision loss or changes
  • Persistent redness lasting more than 3 days
  • Swelling of face, lips, or throat
  • Difficulty breathing
  • Increased heart rate or palpitations
  • Eye discharge or pus

If experiencing severe symptoms, call emergency services immediately.

What is allercool eye drop used for?

This medicine is a combination eye drop containing naphazoline (a decongestant) and chlorpheniramine maleate (an antihistamine). It is used to relieve itching, redness, and swelling caused by allergic conjunctivitis. It works by constricting blood vessels and blocking histamine. Use as directed by your doctor, typically 1-2 drops up to 4 times daily, for no more than 3 days consecutively.

  • Generic Name: Naphazoline + Chlorpheniramine Maleate
  • Manufacturer: Optho Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 allercool eye drop के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जिक कंजंक्टिवाइटिस (आंखों की एलर्जी) से होने वाली खुजली, लालिमा और सूजन को कम करने के लिए आंखों में डालने वाली दवा है। इसमें नैफाजोलिन और क्लोरफेनिरामाइन मेलिएट होते हैं जो आंखों की रक्त वाहिकाओं को सिकोड़ते हैं और हिस्टामिन को रोकते हैं। इसका उपयोग डॉक्टर के निर्देशानुसार ही करें।

साइड इफेक्ट्स: आम दुष्प्रभावों में आंखों में जलन, धुंधली दृष्टि, और सूखापन शामिल हैं। लंबे समय तक उपयोग से आंखें और लाल हो सकती हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि आंखों में तेज दर्द, दृष्टि में बदलाव, या सूजन हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को आंखों में डालने से पहले हाथ धोएं। ड्रॉपर की नोक को किसी सतह से न छुएं। कॉन्टैक्ट लेंस पहनने से पहले निकालें और 10 मिनट बाद ही पहनें। 3 दिन से अधिक लगातार उपयोग न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 allercool eye drop Uses & Benefits

[{"condition":"Allergic conjunctivitis","description":"Relieves itching, redness, and inflammation" class="semantic-link" title="Medicines for swelling">swelling of the conjunctiva caused by allergies.","evidence":"Well-established"},{"condition":"Non-infectious conjunctival hyperemia","description":"Reduces redness due to minor irritants such as smoke, dust, or wind.","evidence":"Well-established"},{"condition":"Ocular decongestion","description":"Provides temporary relief from eye redness by constricting blood vessels.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Prevention of allergic eye symptoms before exposure","description":"Sometimes used prophylactically before known allergen exposure, but not FDA-approved for this use.","evidence":"Limited"}]

Primary treatment for: Allergic conjunctivitis

Also treats: Non-infectious conjunctival hyperemia, Ocular irritation

📋 Drug Information

Generic Name(s)Naphazoline + Chlorpheniramine Maleate
Brand NameAndre Plus Eye Drops
ManufacturerOptho Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassOphthalmic decongestant and antihistamine
Route of AdministrationOphthalmic (topical eye drops)
StorageStore at room temperature (15-30°C). Protect from light and moisture. Keep the bottle tightly closed when not in use.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Use this medicine only for short-term relief, not more than 3 days consecutively.
2
Remove contact lenses before instilling drops and wait 10 minutes before reinserting.
3
Do not touch the dropper tip to your eye or any surface to avoid contamination.
4
If you have high blood pressure or heart disease, consult your doctor before use.
5
Stop use and consult a doctor if redness or irritation persists or worsens.
6
Keep the bottle tightly closed and store at room temperature.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Eye itching
This medicine is commonly prescribed for allergic eye itching.
Likely Use
Eye redness
This medicine helps reduce redness due to allergies or irritants.
Likely Use
Eye pain
This medicine is not for eye pain; consult a doctor.
Not Primary
Blurred vision
This medicine may cause temporary blurred vision but is not a treatment for it.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSystemic absorption after topical ocular administration is minimal but can occur, especially if the nasolacrimal duct is not compressed. Naphazoline and chlorpheniramine may be absorbed into the systemic circulation, potentially causing systemic effects.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionRelief from redness and itching typically begins within minutes after instillation.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effects usually last for 4 to 6 hours, but this can vary.

How It Works

This medicine combines two active ingredients. Naphazoline is an alpha-adrenergic agonist that stimulates alpha receptors on conjunctival blood vessels, causing vasoconstriction and reducing redness and swelling. Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, thereby reducing itching, sneezing, and allergic responses. The combination provides both immediate decongestant and antihistaminic effects.

Mechanism Steps

1
Alpha-adrenergic stimulation: Naphazoline binds to alpha-adrenergic receptors on conjunctival blood vessels, causing vasoconstriction.
2
Vasoconstriction: This constriction reduces blood flow to the conjunctiva, decreasing redness and swelling.
3
Histamine H1 receptor blockade: Chlorpheniramine maleate competitively blocks histamine H1 receptors on conjunctival cells, preventing histamine-mediated itching and allergic responses.
4
Symptom relief: The combined actions provide rapid relief from itching, redness, and irritation.

💡 How to Take allercool eye drop

Strength: Eye drops: Naphazoline 0.05% w/v + Chlorpheniramine maleate 0.1% w/v

1Wash your hands thoroughly with soap and water.
2Shake the bottle gently before use.
3Tilt your head back and pull down your lower eyelid to form a pouch.
4Hold the dropper above the eye and squeeze gently to release 1-2 drops.
5Close your eye and press gently on the inner corner for 1-2 minutes to prevent drainage.
6Wipe away any excess liquid with a clean tissue.
7Replace the cap tightly and wash your hands again.

Dosage Information

Adult DosageInstill 1 to 2 drops into the affected eye(s) up to 4 times daily, or as directed by a physician. Do not exceed the recommended frequency. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustments are established. Use with caution and under medical supervision.
Renal ImpairmentNot established from the available information. Consult a doctor.
Hepatic ImpairmentNot established from the available information. Consult a doctor.
Maximum Daily DoseNot established from the available information. Use only as prescribed.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of allercool eye drop

✅ Common Side Effects

Transient stinging or burning (Common (5-10%))
Usually resolves on its own. If persistent, consult a doctor.
Blurred vision (Common (5-10%))
Avoid driving or operating machinery until vision clears.
Eye irritation (Common (5-10%))
If irritation persists, discontinue use and consult a doctor.

🚨 Serious Side Effects

Rebound conjunctival hyperemia (Uncommon (1-2%))
Discontinue use and consult a doctor if redness worsens after stopping.
Systemic effects (hypertension, palpitations, nervousness) (Rare (<0.1%))
Seek immediate medical attention if you experience these symptoms.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help if you have swelling of face, lips, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Mydriasis (pupil dilation)
Usually temporary. Consult a doctor if persistent.
Increased intraocular pressure
Seek medical attention if you have eye pain or vision changes.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Tricyclic antidepressants Moderate
Other antihistamines Moderate

🚨 Major Interactions

  • MAO inhibitors

⚡ Moderate Interactions

  • Tricyclic antidepressants
  • Other antihistamines

🍷 Alcohol Interaction

Alcohol may increase drowsiness and dizziness. Avoid alcohol while using this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to naphazoline, chlorpheniramine, or any component","Narrow-angle glaucoma","Severe cardiovascular disease","Use in children below the age recommended by a physician"]

⚠️ Warnings & Precautions

["For external use only. Do not swallow.","Do not use for more than 3 days consecutively without medical advice.","Remove contact lenses before use and wait 10 minutes before reinserting.","May cause blurred vision; avoid driving or operating machinery until vision is clear.","Consult a doctor if you have high blood pressure, heart disease, diabetes, or thyroid problems.","Keep out of reach of children."]

🤱 Lactation Safety

Not established from the available information. Consult a doctor before use.

💊 Overdose Management

Overdose from topical ocular use is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of overdose may include drowsiness, hypotension, or tachycardia. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

For topical ophthalmic use only. Wash hands before and after instilling drops. Avoid touching the dropper tip to any surface to prevent contamination. Do not use if the solution changes color or becomes cloudy. Remove soft contact lenses before use and wait at least 10 minutes before reinserting. Do not use for more than 3 days consecutively without medical advice, as prolonged use can cause rebound redness. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before use. Keep out of reach of children. Do not share this medicine with others. If symptoms persist or worsen, stop use and consult an eye specialist.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the systemic effects of naphazoline, such as increased blood pressure. Use with caution and under medical supervision.

🤰 Pregnancy Planning (TTC)

Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this medicine during pregnancy is not established.

🏥 Post-Surgery Considerations

Consult your eye surgeon before using this medicine after eye surgery. It may interfere with healing or increase intraocular pressure.

🦷 Dental Procedures

No specific considerations. Inform your dentist if you are using this medicine.

💚 Lifestyle Tips for Better Results

🏃
Avoid rubbing your eyes, as it can worsen irritation.
🥗
Use cold compresses to soothe allergic eyes.
😴
Identify and avoid allergens that trigger your symptoms.
💧
Wear sunglasses to protect your eyes from dust and wind.
🧘
Maintain good hand hygiene to prevent eye infections.

🏋️ Exercise Considerations

No specific exercise restrictions are established. However, if you experience blurred vision after using the drops, avoid activities that require clear vision until it resolves.

🥗 Diet Recommendations

Include omega-3 rich foods like fish to support eye health.
Stay hydrated to maintain tear production.
Avoid known food allergens that may trigger allergic reactions.

💼 Impact on Daily Work & Life

This medicine may cause temporary blurred vision. Avoid driving or operating heavy machinery until your vision is clear. It does not otherwise affect your ability to work.

🛑 When to Stop This Medicine

Stop using this medicine if your symptoms do not improve within 3 days, or if you experience increased redness, pain, or vision changes. Consult a doctor before resuming use.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to rebound conjunctival hyperemia, where the eyes become redder when the drops are stopped. It may also cause systemic effects such as increased blood pressure. Therefore, it should only be used for short-term relief under medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Cold compress

Applying a cold compress can help reduce eye swelling and soothe irritation.

Evidence: Well-established
Avoidance of allergens

Identifying and avoiding triggers can prevent allergic conjunctivitis.

Evidence: Well-established
Lubricating eye drops

Artificial tears can help flush out allergens and soothe eyes.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, consult your doctor before vaccination if you are using this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling by air, keep it in your carry-on luggage. No time zone adjustments are needed for eye drops. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with seasonal allergic conjunctivitis
She experienced severe itching and redness in both eyes during spring. Her doctor prescribed this medicine. After using it for 2 days, her symptoms improved significantly. She was advised not to use it for more than 3 days and to avoid contact lenses during treatment.
💡 Lesson: Short-term use of this medicine provides effective relief from allergic eye symptoms, but prolonged use should be avoided.
👤 A 45-year-old man with red eyes due to dust exposure
He used this medicine for quick relief from redness. After 4 days of continuous use, his eyes became redder. He consulted a doctor who explained that this was rebound redness due to overuse. He was advised to stop the drops and use lubricating eye drops instead.
💡 Lesson: Prolonged use of decongestant eye drops can cause rebound redness. Always follow the prescribed duration.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Relief from redness and itching typically begins within minutes after instillation.

Q: How long can I use this medicine?

A: It should not be used for more than 3 days consecutively without medical advice.

Q: Is it safe for children?

A: Pediatric dosing is not established. Consult a pediatrician before use.

Q: Can I use it with contact lenses?

A: Remove contact lenses before use and wait at least 10 minutes before reinserting.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine daily?
  • Will it affect my blood pressure?
  • Can I drive after using this medicine?
  • Does it interact with my other eye drops?
  • What if I miss a dose?
  • Can I drink alcohol while using this?

🔄 Substitutes for allercool eye drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Allercool eye drops can be used indefinitely for red eyes.
    Fact: Prolonged use can cause rebound redness and should be limited to short-term use as prescribed.
  • Myth: Allercool eye drops are safe for everyone.
    Fact: They are contraindicated in narrow-angle glaucoma and severe cardiovascular disease.

🔄 Alternative Options

Generic Alternatives

  • Naphazoline + Chlorpheniramine eye drops

📊 Comparison with Similar Medicines

[{"medicine":"Allercool Eye Drop","active_ingredient":"Naphazoline + Chlorpheniramine","class":"Decongestant + Antihistamine","primary_use":"Allergic conjunctivitis","duration":"Short-term"},{"medicine":"Ketotifen eye drops","active_ingredient":"Ketotifen","class":"Antihistamine + Mast cell stabilizer","primary_use":"Allergic conjunctivitis","duration":"Long-term"}]

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