Apache-TH4 Tablet - Uses, Price, Side Effects
What is apache-th4 tablet used for?
Apache-TH4 Tablet is a combination medicine containing Thiocolchicoside (4mg) and Aceclofenac (100mg). It is used to relieve pain and inflammation associated with muscle spasms, such as in back pain, neck pain, and joint disorders. Thiocolchicoside acts as a muscle relaxant, while Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and swelling.
- Generic Name: Thiocolchicoside + Aceclofenac
- Manufacturer: Nitro Organics
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ apache-th4 tablet Uses & Benefits
Acute musculoskeletal pain, muscle spasms, inflammatory conditions
Off-label uses: Not well established
๐ Drug Information
| Generic Name(s) | Thiocolchicoside + Aceclofenac |
| Brand Name | Anaflam TH 4 Tablet |
| Manufacturer | Nitro Organics |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Muscle Relaxant + NSAID |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Thiocolchicoside: Acts on GABA-A and glycine receptors to produce muscle relaxation; Aceclofenac: Inhibits COX-1 and COX-2, reducing prostaglandin synthesis
Mechanism Steps
๐ก How to Take apache-th4 tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of apache-th4 tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Dizziness
- Somnolence
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Renal failure
- Hepatotoxicity
- Anaphylaxis
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Stevens-Johnson syndrome
- Seizures
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Moderate | Increased methotrexate toxicity |
| Lithium | Moderate | Increased lithium levels |
| Aspirin | Moderate | Increased risk of gastrointestinal bleeding |
| Cyclosporine | Moderate | Increased nephrotoxicity |
๐จ Major Interactions
- Warfarin
- Lithium
- Methotrexate
- Aspirin
- Other NSAIDs
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- Anticoagulants
- Corticosteroids
โน๏ธ Minor Interactions
- Antacids
- Digoxin
- Phenytoin
๐ฝ๏ธ Food Interactions
May be taken with food to reduce GI upset
๐ท Alcohol Interaction
Increased risk of GI bleeding and hepatotoxicity
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active peptic ulcer, severe renal/hepatic impairment, pregnancy (third trimester), lactation, children <16 years
๐ Monitoring Parameters
Liver function, renal function, blood pressure, GI symptoms
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Symptomatic and supportive; gastric lavage, activated charcoal
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose