anxibrium t tablet - Chlordiazepoxide (10mg) + Trifluoperazine (1mg) medicine

Anxibrium T Tablet - Uses, Price, Side Effects

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🏭 Theo Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

What is anxibrium t tablet used for?

Anxibrium T Tablet is a combination of Chlordiazepoxide (10mg) and Trifluoperazine (1mg) used to treat anxiety and tension. Chlordiazepoxide is a benzodiazepine that enhances GABA activity to reduce anxiety, while Trifluoperazine is a phenothiazine antipsychotic that blocks dopamine receptors to calm the mind. It is typically taken twice daily as prescribed.

  • Generic Name: Chlordiazepoxide + Trifluoperazine
  • Manufacturer: Theo Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 anxibrium t tablet Uses & Benefits

Anxiety disorders, psychotic disorders, nausea/vomiting (off-label)

Off-label uses: Severe nausea/vomiting, agitation in dementia

📋 Drug Information

Generic Name(s)Chlordiazepoxide + Trifluoperazine
Brand NameAngirex Tablet
ManufacturerTheo Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassBenzodiazepine + Phenothiazine Antipsychotic
Route of AdministrationOral
StorageStore at 20-25°C, protect from light and moisture
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionWidely distributed; crosses blood-brain barrier
Protein BindingChlordiazepoxide: 96-98%; Trifluoperazine: 90-99%
MetabolismHepatic (CYP3A4 for chlordiazepoxide; multiple pathways for trifluoperazine)
Half-LifeChlordiazepoxide: 5-30 hours; Trifluoperazine: 12-30 hours
ExcretionRenal (as metabolites)
BioavailabilityChlordiazepoxide: ~100%; Trifluoperazine: ~40-50%
Onset of Action30-60 minutes
Peak Plasma TimeChlordiazepoxide: 1-4 hours; Trifluoperazine: 2-5 hours
Duration of Action6-8 hours

How It Works

Chlordiazepoxide enhances GABA-A receptor activity; Trifluoperazine blocks dopamine D2 receptors

Mechanism Steps

1Chlordiazepoxide binds to GABA-A receptor benzodiazepine site
2Enhances GABA affinity, increasing chloride ion influx
3Hyperpolarizes neuron, reducing excitability
4Trifluoperazine blocks D2 dopamine receptors in mesolimbic pathway
5Reduces dopaminergic neurotransmission
6Combined effect: anxiolytic, sedative, antipsychotic

💡 How to Take anxibrium t tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of anxibrium t tablet

✅ Common Side Effects

Drowsiness
Dizziness
Dry mouth
Blurred vision
Constipation
Weight gain

🚨 Serious Side Effects

Extrapyramidal symptoms
Tardive dyskinesia
Neuroleptic malignant syndrome
Respiratory depression
Blood dyscrasias

⚠️ Rare Side Effects

Jaundice
Agranulocytosis
Seizures
QT prolongation

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Alcohol Major Increased CNS depression and sedation
MAOIs Major Hypertensive crisis
CNS Depressants Major Additive sedation and respiratory depression

🚨 Major Interactions

  • MAOIs
  • CNS depressants (alcohol, opioids)
  • Anticholinergics
  • Levodopa
  • Lithium

⚡ Moderate Interactions

  • Antihypertensives
  • Antidiabetics
  • CYP3A4 inhibitors/inducers

🍷 Alcohol Interaction

Avoid; additive CNS depression

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, coma, severe CNS depression, narrow-angle glaucoma, bone marrow suppression, liver failure

🤱 Lactation Safety

Not recommended; excreted in breast milk

💊 Overdose Management

Supportive care; activated charcoal; flumazenil for chlordiazepoxide; avoid epinephrine for hypotension

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double

🔄 Substitutes for anxibrium t tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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