amrobrut cream - Amorolfine (0.25% w/w) + Phenoxyethanol (1% w/w) medicine

amrobrut cream

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🏭 Mankind Pharma Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

What is amrobrut cream used for?

This medicine contains Amorolfine (0.25% w/w) + Phenoxyethanol (1% w/w) and is used to treat DERMA. Inhibition of fungal ergosterol synthesis (amorolfine) and disruption of microbial cell membranes (p. Always consult your doctor before use.

  • Generic Name: Amorolfine + Phenoxyethanol
  • Manufacturer: Mankind Pharma Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 amrobrut cream Uses & Benefits

Topical treatment of dermatophyte infections (tinea pedis, tinea cruris, tinea corporis), cutaneous candidiasis, and pityriasis versicolor

Off-label uses: Onychomycosis (nail infections) - limited evidence

📋 Drug Information

Generic Name(s)Amorolfine + Phenoxyethanol
Brand NameAmortas Cream
ManufacturerMankind Pharma Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntifungal
Route of AdministrationTopical
StorageStore at room temperature (15-30°C); keep tightly closed
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMinimal systemic absorption after topical application
DistributionLocalized to skin; negligible systemic distribution
Protein BindingNot applicable (topical)
MetabolismNot significantly metabolized systemically
Half-LifeNot applicable (topical)
ExcretionNot applicable (topical)
BioavailabilityNot applicable (topical)
Onset of ActionWithin 24-48 hours
Peak Plasma TimeNot applicable (topical)
Duration of ActionUp to 7 days after single application

How It Works

Inhibition of fungal ergosterol synthesis (amorolfine) and disruption of microbial cell membranes (phenoxyethanol)

Mechanism Steps

1Amorolfine inhibits fungal 14α-demethylase, blocking ergosterol synthesis
2Ergosterol depletion disrupts fungal cell membrane integrity
3Phenoxyethanol disrupts microbial cell membranes via denaturation of proteins and increased permeability
4Combined action leads to fungal cell death

💡 How to Take amrobrut cream

Follow your doctor's prescription exactly.

⚠️ Side Effects of amrobrut cream

✅ Common Side Effects

Application site burning
itching
redness
dryness

🚨 Serious Side Effects

Severe allergic reaction (rare)
angioedema

⚠️ Rare Side Effects

Contact dermatitis
skin discoloration

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to amorolfine, phenoxyethanol, or any excipients

🤱 Lactation Safety

Likely safe; minimal systemic absorption

💊 Overdose Management

Not expected with topical use; accidental ingestion may cause gastrointestinal irritation; symptomatic treatment

⏰ Missed Dose

Apply as soon as remembered; skip if almost time for next dose; do not double dose

🔄 Substitutes for amrobrut cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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