ampoxid 250 mg/250 mg capsule - Ampicillin (250mg) + Dicloxacillin (250mg) medicine

Ampoxid 250 mg/250 mg Capsule: Complete Medicine Guide

No reviews yet
🏭 Torrent Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for susceptible bacterial infections.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe or bloody diarrhea
  • Yellowing of skin or eyes
  • Decreased urine output or swelling in legs
  • Severe abdominal pain
  • Unusual bleeding or bruising
  • Seizures or confusion

If experiencing severe symptoms, call emergency services immediately.

What is ampoxid 250 mg/250 mg capsule used for?

This medicine is a combination antibiotic containing ampicillin and dicloxacillin, used to treat bacterial infections of the skin, respiratory tract, and urinary tract. It works by killing bacteria and should be taken exactly as prescribed.

  • Generic Name: Ampicillin (250mg) + Dicloxacillin (250mg)
  • Manufacturer: Torrent Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ampoxid 250 mg/250 mg capsule के बारे में (Hindi Summary)

उपयोग: यह दवा एम्पीसिलिन और डाइक्लोक्सासिलिन का संयोजन है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह त्वचा, श्वसन तंत्र और मूत्र मार्ग के संक्रमणों के लिए निर्धारित की जाती है। यह बैक्टीरिया को मारकर काम करती है। इसे डॉक्टर के निर्देशानुसार पूरा कोर्स लेना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, गंभीर दस्त और यकृत की समस्या हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक न छोड़ें और कोर्स पूरा करें। इसे पानी के साथ लें, भोजन के साथ या बिना भी ले सकते हैं। यदि आपको पेनिसिलिन से एलर्जी है तो डॉक्टर को बताएं। शराब से बचें। गंभीर दस्त, चकत्ते या सांस लेने में कठिनाई हो तो तुरंत मदद लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 ampoxid 250 mg/250 mg capsule Uses & Benefits

[{"condition":"Skin and soft tissue infections","description":"Used to treat bacterial skin infections such as cellulitis, impetigo, folliculitis, and infected wounds caused by susceptible gram-positive and gram-negative bacteria.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"May be prescribed for upper and lower respiratory tract infections including sinusitis, pharyngitis, and pneumonia when caused by susceptible organisms.","evidence":"Established"},{"condition":"Urinary tract infections","description":"Sometimes used for urinary tract infections caused by susceptible bacteria, though other antibiotics are often preferred.","evidence":"Limited"},{"condition":"Dental infections","description":"Can be used for dental abscesses and periodontal infections when appropriate.","evidence":"Established"}]

Off-label uses: [{"condition":"Prophylaxis in dental procedures","description":"Occasionally used off-label for prevention of endocarditis in high-risk patients undergoing dental procedures, but not a standard recommendation.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Skin and soft tissue infections, Respiratory tract infections, Urinary tract infections, Dental infections

📋 Drug Information

Generic Name(s)Ampicillin (250mg) + Dicloxacillin (250mg)
Brand Nameampoxid 250 mg/250 mg capsule
ManufacturerTorrent Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full prescribed course even if you feel better after a few days.
3
Stay well hydrated throughout the day to help your kidneys flush the medicine.
4
Avoid alcohol while taking this medicine as it may worsen side effects.
5
Do not share this medicine with others, even if they have similar symptoms.
6
Report any unusual bleeding, bruising, or severe diarrhea to your doctor immediately.
7
If you miss a dose, take it as soon as you remember, but do not double the dose.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Skin infection with redness and swelling
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Cough with yellow sputum
May be used for respiratory infections.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmpicillin and dicloxacillin are both absorbed from the gastrointestinal tract. Food may slightly reduce absorption of dicloxacillin, but the clinical significance is minimal. Absorption is generally adequate for therapeutic effect.
DistributionBoth agents distribute widely into body tissues and fluids, including skin, soft tissues, and respiratory secretions. They do not penetrate the cerebrospinal fluid well unless the meninges are inflamed.
Protein BindingAmpicillin is approximately 20% protein-bound; dicloxacillin is approximately 95-98% protein-bound.
MetabolismAmpicillin is partially metabolized in the liver to inactive metabolites. Dicloxacillin is extensively metabolized in the liver.
Half-LifeAmpicillin half-life is about 1 to 1.5 hours; dicloxacillin half-life is about 0.5 to 0.7 hours. Both are prolonged in renal impairment.
ExcretionBoth drugs are excreted primarily in the urine, partly unchanged and partly as metabolites. Renal impairment can lead to accumulation.
BioavailabilityAmpicillin bioavailability is approximately 30-55% orally; dicloxacillin bioavailability is approximately 35-76% orally.
Onset of ActionAntibacterial effect begins within 1-2 hours after oral administration, but clinical improvement may take 24-48 hours.
Peak Plasma TimeAmpicillin peak plasma time is 1-2 hours; dicloxacillin peak plasma time is 0.5-2 hours.
Duration of ActionThe antibacterial effect lasts approximately 6-8 hours, requiring dosing every 6 hours for optimal coverage.

How It Works

This medicine works by inhibiting bacterial cell wall synthesis. Ampicillin and dicloxacillin bind to penicillin-binding proteins (PBPs) on the inner bacterial membrane, blocking the cross-linking of peptidoglycan chains. This weakens the cell wall, causing bacterial lysis and death. Dicloxacillin is resistant to penicillinase enzymes produced by Staphylococcus aureus, while ampicillin extends coverage to certain gram-negative bacteria.

Mechanism Steps

1
Binding to penicillin-binding proteins: Ampicillin and dicloxacillin bind to specific PBPs on the bacterial cell membrane.
2
Inhibition of cell wall cross-linking: This binding blocks the transpeptidation reaction needed for peptidoglycan cross-linking.
3
Activation of autolysins: The weakened cell wall triggers autolytic enzymes that further degrade the peptidoglycan.
4
Bacterial lysis and death: The bacterial cell bursts due to osmotic pressure, leading to death of the organism.

💡 How to Take ampoxid 250 mg/250 mg capsule

Strength: Capsule containing ampicillin 250 mg and dicloxacillin 250 mg.

1Take this medicine by mouth with a full glass of water.
2You may take it with or without food, but food may reduce stomach upset.
3Swallow the capsule whole. Do not crush or chew.
4Take at evenly spaced intervals as prescribed by your doctor.
5Complete the full course of therapy even if you feel better.
6Do not share this medicine with others.

Dosage Information

Adult DosageThe usual adult dose is one capsule (250 mg ampicillin + 250 mg dicloxacillin) taken orally every 6 hours, or as prescribed by your doctor. The dose may be adjusted based on the type and severity of infection, kidney function, and liver function. Always follow your doctor's instructions. Do not self-adjust the dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced renal function and may require dose adjustment. Use with caution and monitor renal function. Dose must be individualized by a qualified clinician.
Renal ImpairmentDose adjustment is required in patients with renal impairment. For creatinine clearance less than 10 mL/min, the dosing interval may need to be extended. Consult your doctor for specific recommendations.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Monitor liver function. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is not established from available information. Follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
No specific restriction
No known interaction.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ampoxid 250 mg/250 mg capsule

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce nausea. If persistent, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or bloody, seek medical attention.
Vomiting (Common (5-10%))
Take with food and fluids. If vomiting prevents keeping the medicine down, contact your doctor.
Skin rash (Uncommon (1-5%))
Stop the medicine and consult your doctor if rash appears, as it may indicate allergy.
Stomach pain (Common (5-10%))
Take with food. If pain is severe or persistent, consult your doctor.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek emergency medical help immediately if you experience difficulty breathing, swelling of face or throat, or severe dizziness.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek medical attention if you develop severe, persistent diarrhea, abdominal cramps, or fever.
Hepatotoxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or right upper abdominal pain to your doctor immediately.
Interstitial nephritis (Rare (<0.1%))
Seek medical attention if you notice decreased urine output, swelling, or blood in urine.
Seizures (Very rare (<0.01%))
This is more likely with high doses in renal impairment. Seek emergency care if seizures occur.

⚠️ Rare Side Effects

Blood dyscrasias
Report unusual bruising or bleeding to your doctor.
Serum sickness-like reaction
Consult your doctor if you experience fever, joint pain, and rash.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
Tetracyclines Moderate
Allopurinol Moderate
Oral contraceptives Moderate
Probenecid Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Tetracyclines

⚡ Moderate Interactions

  • Allopurinol
  • Oral contraceptives
  • Probenecid

🍷 Alcohol Interaction

Alcohol may worsen stomach upset and dizziness. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to penicillins or cephalosporins","History of severe allergic reaction to any beta-lactam antibiotic","Infectious mononucleosis (increased risk of rash)","Concurrent use with tetracyclines (antagonism)"]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment; dose adjustment may be needed.","Use with caution in patients with hepatic impairment.","May cause false-positive results in urine glucose tests.","Prolonged use may lead to superinfection with resistant organisms.","Ensure adequate hydration during therapy.","Do not use for viral infections.","Complete the full course as prescribed."]

🤱 Lactation Safety

Ampicillin and dicloxacillin are excreted in breast milk in small amounts. Use with caution; monitor infant for diarrhea or thrush. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhea, and electrolyte imbalance. In severe cases, seizures may occur, especially in renal impairment. Treatment is symptomatic and supportive. Hemodialysis may be considered for ampicillin removal. Contact a poison control center or emergency department immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Take with a full glass of water, with or without food, but food may reduce stomach upset. Inform your doctor if you have kidney or liver problems, or if you are allergic to penicillin or cephalosporin antibiotics. Avoid alcohol while taking this medicine as it may worsen stomach upset and dizziness. If you experience severe diarrhea, rash, or difficulty breathing, seek medical help immediately. Do not share this medicine with others. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function and may require dose adjustment. Monitor renal function and watch for signs of toxicity.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It is generally considered safe in pregnancy (Category B), but use only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions carefully.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may be used for dental infections or prophylaxis in certain cases.

💚 Lifestyle Tips for Better Results

🏃
Maintain good hygiene to prevent infections.
🥗
Eat a balanced diet to support your immune system.
😴
Stay well hydrated.
💧
Get adequate rest to help your body fight infection.
🧘
Avoid sharing personal items like towels and razors.

🏋️ Exercise Considerations

You can continue light exercise as tolerated, but avoid strenuous activity if you feel weak or dizzy. Consult your doctor before resuming intense workouts.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to maintain gut health.
Stay well hydrated.
Avoid alcohol.
Eat a balanced diet with plenty of fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or stomach upset. Avoid driving or operating heavy machinery if you feel dizzy. You can usually continue normal daily activities as tolerated.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Complete the full prescribed course even if you feel better. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to antibiotic resistance, superinfections, and rare blood or liver abnormalities. It is generally prescribed for short courses. Prolonged use should be monitored by a doctor with regular blood tests.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Other antibiotics

Depending on the infection and culture results, other antibiotics may be more appropriate.

Evidence: Well-established
Topical antibiotics

For minor skin infections, topical antibiotics may be sufficient.

Evidence: Established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Continue routine vaccinations as scheduled. Inform your doctor if you are due for any live vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing intervals as advised by your doctor. Declare it at customs if required. Keep it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with a skin infection on his leg
He was prescribed this medicine for cellulitis. He took it with food to avoid stomach upset and completed the 7-day course. His infection cleared completely, and he felt better within 3 days.
💡 Lesson: Taking the medicine with food and completing the full course leads to successful treatment.
👤 A 50-year-old woman with a dental abscess
She started this medicine as prescribed and noticed improvement in pain and swelling within 2 days. She experienced mild nausea, which was managed by taking the medicine with meals.
💡 Lesson: Mild side effects can be managed with food, and completing the course prevents recurrence.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24-48 hours, but you must complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ampoxid 250 mg/250 mg capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure viral infections like the common cold.
    Fact: This medicine is effective only against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking antibiotics once you feel better.
    Fact: You must complete the full prescribed course to prevent recurrence and resistance.
  • Myth: Antibiotics can be shared with others who have similar symptoms.
    Fact: Never share antibiotics. They are prescribed for a specific infection and person.

🔄 Alternative Options

Generic Alternatives

  • Ampicillin and dicloxacillin combination capsules are available generically.

Brand Alternatives

  • Ampoxid 250 mg/250 mg capsule

📊 Comparison with Similar Medicines

[{"medicine":"Ampicillin + Dicloxacillin","class":"Penicillin combination","coverage":"Broad-spectrum with penicillinase-resistant coverage","route":"Oral"},{"medicine":"Amoxicillin + Clavulanate","class":"Penicillin + beta-lactamase inhibitor","coverage":"Broad-spectrum including beta-lactamase producers","route":"Oral"},{"medicine":"Cloxacillin","class":"Penicillinase-resistant penicillin","coverage":"Gram-positive bacteria including Staphylococcus","route":"Oral"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory