amlopin-m tablet pr
What is amlopin-m tablet pr used for?
This medicine contains Amlodipine (5mg) + Metoprolol Succinate (50mg) and is used to treat CARDIAC. Amlodipine inhibits calcium influx across cell membranes, causing vasodilation; Metoprolol selective. Always consult your doctor before use.
- Generic Name: Amlodipine + Metoprolol Succinate
- Manufacturer: USV Ltd
- Form: Allopathy
- Pregnancy Category: Category A
- Prescription Required: Yes
💊 amlopin-m tablet pr Uses & Benefits
Hypertension, stable angina, chronic heart failure (metoprolol).
Off-label uses: Migraine prophylaxis (metoprolol), Raynaud's phenomenon (amlodipine).
📋 Drug Information
| Generic Name(s) | Amlodipine + Metoprolol Succinate |
| Brand Name | Amtas-M 50 Tablet PR |
| Manufacturer | USV Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antihypertensive combination (Calcium channel blocker + Beta-blocker) |
| Route of Administration | Oral |
| Storage | Store at 20-25°C, protect from light and moisture. |
| Shelf Life | As per manufacturer |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Amlodipine inhibits calcium influx across cell membranes, causing vasodilation; Metoprolol selectively blocks beta-1 adrenergic receptors, reducing heart rate and contractility.
Mechanism Steps
💡 How to Take amlopin-m tablet pr
Follow your doctor's prescription exactly.
⚠️ Side Effects of amlopin-m tablet pr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased amlodipine levels, risk of toxicity |
| Fluoxetine | Major | Increased metoprolol levels, bradycardia |
| NSAIDs | Moderate | Reduced antihypertensive effect |
| Digoxin | Moderate | Increased risk of bradycardia |
| Grapefruit juice | Minor | Increased amlodipine absorption |
🚨 Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole)
- CYP2D6 inhibitors (e.g., fluoxetine)
- Beta-blockers (additive bradycardia)
- Calcium channel blockers (additive hypotension)
⚡ Moderate Interactions
- NSAIDs
- Digoxin
- Clonidine
- Cimetidine
🍷 Alcohol Interaction
May enhance hypotensive effects; avoid excessive alcohol.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity, cardiogenic shock, severe bradycardia, heart block, sick sinus syndrome, uncontrolled heart failure, severe hypotension.
🤱 Lactation Safety
Excreted in breast milk; use with caution.
💊 Overdose Management
Supportive care; atropine for bradycardia, vasopressors for hypotension, calcium gluconate for amlodipine overdose.
⏰ Missed Dose
Take as soon as remembered; skip if near next dose; do not double.
🔄 Substitutes for amlopin-m tablet pr
View AllAlternative brands with exact same active ingredient:
-
metolash am 5mg/50mg tabletZeelab Pharmacy Pvt Ltd ₹15.00 89.8% CHEAPER
-
davaindia amlodipine+metoprolol succinate 5mg/50mg tablet prDavaindia Generic Pharmacy ₹17.60 88.1% CHEAPER
-
bpdin mt 50 tablet erDR Best pharmaceuticals Pvt Ltd ₹23.44 84.1% CHEAPER
-
acmeto am 5mg/50mg tabletAcmedix Pharma LLP ₹25.31 82.9% CHEAPER
-
mepol-a 5mg/50mg tabletTaurus Laboratories Pvt Ltd ₹27.89 81.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.