amlip 2.5 tablet - Amlodipine (2.5mg) medicine

amlip 2.5 tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Cipla Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is amlip 2.5 tablet used for?

Amlokind 5 Tablet (Amlodipine) is used to treat CARDIAC. It contains Amlodipine (2.5mg), which Inhibits calcium ion influx across cardiac and vascular smooth muscle cells, lea. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Amlodipine
  • Manufacturer: Cipla Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š amlip 2.5 tablet Uses & Benefits

Hypertension, chronic stable angina, vasospastic angina (Prinzmetal's angina).

Off-label uses: Raynaud's phenomenon, migraine prophylaxis, high-altitude pulmonary edema.

๐Ÿ“‹ Drug Information

Generic Name(s)Amlodipine
Brand NameAmlokind 5 Tablet
ManufacturerCipla Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassCalcium channel blockers- Dihydropyridines (DHP)
Route of AdministrationOral.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration with peak plasma concentrations achieved within 6-12 hours.
DistributionExtensively distributed with a large volume of distribution (about 21 L/kg).
Protein BindingApproximately 93% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via CYP3A4 isoenzyme to inactive metabolites.
Half-Life30-50 hours (terminal elimination half-life).
ExcretionPrimarily excreted as metabolites in urine (about 60%) and feces (20-25%).
Bioavailability64-90% (oral bioavailability).
Onset of ActionGradual onset; antihypertensive effect seen within 2-4 hours.
Peak Plasma Time6-12 hours.
Duration of Action24 hours (once-daily dosing).

How It Works

Inhibits calcium ion influx across cardiac and vascular smooth muscle cells, leading to vasodilation and reduced peripheral vascular resistance.

Mechanism Steps

1Binds to L-type calcium channels in vascular smooth muscle and cardiac myocytes.
2Inhibits calcium ion influx during depolarization.
3Reduces intracellular calcium concentration.

๐Ÿ’ก How to Take amlip 2.5 tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of amlip 2.5 tablet

โœ… Common Side Effects

  • Edema (peripheral)
  • Dizziness
  • Flushing
  • Palpitations
  • Fatigue
  • Nausea

๐Ÿšจ Serious Side Effects

  • Severe hypotension
  • Myocardial infarction (rare)
  • Hepatotoxicity (rare)
  • Stevens-Johnson syndrome (rare)

โš ๏ธ Rare Side Effects

  • Gingival hyperplasia
  • Gynecomastia
  • Leukopenia
  • Vasculitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
CYP3A4 inhibitors Major Increased amlodipine exposure, risk of toxicity
CYP3A4 inducers Major Decreased amlodipine efficacy
Simvastatin Major Increased risk of myopathy/rhabdomyolysis
Grapefruit juice Moderate Increased amlodipine levels
Diltiazem Moderate Increased amlodipine levels
Clarithromycin Moderate Increased amlodipine levels
Antacids Minor Slight decrease in amlodipine absorption
Sildenafil Minor Additive hypotensive effect

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine)
  • Simvastatin

โšก Moderate Interactions

  • Grapefruit juice
  • Diltiazem
  • Clarithromycin

โ„น๏ธ Minor Interactions

  • Antacids
  • Sildenafil

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase amlodipine levels.

๐Ÿท Alcohol Interaction

Alcohol may potentiate the hypotensive effect.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to amlodipine or dihydropyridines, severe hypotension, cardiogenic shock.

๐Ÿ“Š Monitoring Parameters

Blood pressure, heart rate, peripheral edema, liver function tests.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised.

๐Ÿ’Š Overdose Management

Gastric lavage, activated charcoal, supportive care; calcium gluconate may be beneficial.

โฐ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for amlip 2.5 tablet

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Alternative brands with exact same active ingredient (Amlodipine (2.5mg)):

Medical Note: Always consult your doctor before switching medications.

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