amlice t syrup - Ambroxol (15mg/5ml) + Guaifenesin (100mg/5ml) medicine

Ambroxol + Guaifenesin Syrup: Complete Medicine Guide

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🏭 Alice Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
🤰 Pregnancy Category Not established from the available information. Consult your doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate for ambroxol and guaifenesin in productive cough; limited for combination.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or shortness of breath
  • Chest pain or tightness
  • Coughing up blood
  • High fever (above 101°F) lasting more than 3 days
  • Severe headache with stiff neck
  • Swelling of face, lips, or throat
  • Rash or hives
  • Confusion or extreme drowsiness

If experiencing severe symptoms, call emergency services immediately.

What is amlice t syrup used for?

This medicine is a combination syrup containing ambroxol and guaifenesin, used to treat productive cough by thinning and loosening mucus in the airways. It is typically taken 2-3 times daily for short-term relief.

  • Generic Name: Ambroxol + Guaifenesin
  • Manufacturer: Alice Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 amlice t syrup के बारे में (Hindi Summary)

उपयोग: यह दवा बलगम वाली खांसी के इलाज के लिए इस्तेमाल की जाती है। यह गले और फेफड़ों में जमा गाढ़े बलगम को पतला करके बाहर निकालने में मदद करती है। यह आम सर्दी, ब्रोंकाइटिस और अन्य श्वसन संबंधी समस्याओं में लाभकारी है।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में जी मिचलाना, उल्टी, पेट में असहजता, दस्त और नींद आना शामिल हैं। कभी-कभी एलर्जी, चक्कर आना या सिरदर्द भी हो सकता है। गंभीर दुष्प्रभाव बहुत दुर्लभ हैं।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे लेने से पहले बोतल को अच्छी तरह हिलाएं। सही मात्रा मापने के लिए दवा के साथ दिया गया कप या सिरिंज का उपयोग करें। इस दवा से नींद आ सकती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 amlice t syrup Uses & Benefits

[{"condition":"Productive cough (wet cough)","description":"Helps loosen thick mucus in the airways, making it easier to cough up and clear the chest.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Used to relieve cough and mucus congestion associated with acute inflammation of the bronchi.","evidence":"Well-established"},{"condition":"Common cold with chest congestion","description":"Provides symptomatic relief by thinning mucus and reducing cough effort.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD) with mucus hypersecretion","description":"May help in clearing mucus in some patients with chronic bronchitis component of COPD.","evidence":"Limited"}]

Off-label uses: [{"condition":"Prevention of respiratory distress syndrome in premature infants","description":"Ambroxol has been studied off-label for this purpose, but it is not a standard use for the oral syrup formulation.","evidence":"Limited"},{"condition":"Sinusitis with thick secretions","description":"Sometimes used off-label to help thin sinus secretions, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Productive cough

Also treats: Acute bronchitis, Common cold with chest congestion, COPD with mucus hypersecretion

📋 Drug Information

Generic Name(s)Ambroxol + Guaifenesin
Brand NameAmbrolite-S Expectorant
ManufacturerAlice Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic and Expectorant
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. Do not refrigerate unless specified on the label.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce the risk of stomach upset.
2
Stay well hydrated by drinking plenty of water throughout the day to help thin mucus.
3
Avoid alcohol while taking this medicine as it can increase drowsiness.
4
Do not take more than the prescribed dose; more is not better.
5
If your cough does not improve within 7 days, consult your doctor.
6
Do not use this medicine with cough suppressants unless advised by a doctor.
7
Keep track of your symptoms to share with your doctor at follow-up.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
Dry cough
This medicine is not effective for dry cough.
Not Primary
Chest congestion
This medicine helps loosen mucus in the chest.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmbroxol is rapidly absorbed from the gastrointestinal tract after oral administration. Guaifenesin is also absorbed from the gastrointestinal tract. The presence of food may slightly delay the absorption of guaifenesin but does not significantly affect the overall extent of absorption.
DistributionAmbroxol is widely distributed in body tissues, including the lungs, and crosses the blood-brain barrier and placental barrier. Guaifenesin is also distributed throughout body fluids and tissues. Protein binding information for both ingredients is not well established from available sources.
Protein BindingNot established from the available information.
MetabolismAmbroxol is primarily metabolized in the liver by cytochrome P450 enzymes, mainly CYP3A4, to inactive metabolites. Guaifenesin is metabolized in the liver, but the specific enzymes involved are not fully characterized.
Half-LifeThe elimination half-life of ambroxol is approximately 7 to 12 hours. The elimination half-life of guaifenesin is approximately 1 hour.
ExcretionAmbroxol and its metabolites are primarily excreted in the urine. Guaifenesin and its metabolites are also excreted mainly in the urine.
BioavailabilityThe oral bioavailability of ambroxol is approximately 70-80% due to first-pass metabolism. The oral bioavailability of guaifenesin is approximately 50%.
Onset of ActionThe onset of action for ambroxol is typically within 30 minutes to 1 hour after oral administration. Guaifenesin also begins to work within 30 minutes to 1 hour.
Peak Plasma TimePeak plasma concentrations of ambroxol are reached approximately 1 to 3 hours after oral administration. Peak plasma concentrations of guaifenesin are reached within 15 to 30 minutes.
Duration of ActionThe duration of action for ambroxol is approximately 6 to 12 hours. The duration of action for guaifenesin is approximately 4 to 6 hours.

How It Works

This medicine combines two active ingredients with complementary actions. Ambroxol is a mucolytic that breaks down the structure of mucus by altering the composition of mucopolysaccharide fibers, making the mucus less viscous and easier to clear. It also stimulates the production of surfactant in the lungs, which helps to reduce mucus adhesion to the airway walls. Guaifenesin is an expectorant that works by increasing the volume and reducing the viscosity of bronchial secretions, likely by irritating the gastric mucosa and reflexively stimulating respiratory tract secretions. Together, they thin and loosen mucus, making coughs more productive and helping to clear the airways.

Mechanism Steps

1
Ambroxol breaks down mucus structure: Ambroxol alters the chemical bonds in mucus glycoproteins, reducing the thickness and stickiness of secretions.
2
Ambroxol stimulates surfactant production: It increases surfactant in the alveoli, which helps prevent mucus from sticking to airway walls.
3
Guaifenesin increases mucus water content: Guaifenesin draws water into bronchial secretions, further thinning the mucus and increasing its volume.
4
Enhanced ciliary clearance: Thinner mucus is more easily moved by the cilia lining the airways, leading to a more effective cough.

💡 How to Take amlice t syrup

Strength: Each 5 ml of syrup contains ambroxol 15 mg and guaifenesin 100 mg.

1Shake the bottle well before each use.
2Use the measuring cup or oral syringe provided to measure the correct dose.
3Take the medicine orally, with or without food.
4If taking with food, take it with meals to reduce stomach upset.
5After taking, close the bottle tightly and store it properly.
6Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 10 ml (which provides 30 mg ambroxol and 200 mg guaifenesin) taken orally two to three times daily. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, and renal and hepatic function. Do not exceed the recommended dose. Always follow your doctor's prescription.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, particularly drowsiness and dizziness. Dose adjustment may be necessary based on renal and hepatic function. Consult a doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be required in patients with impaired kidney function. Consult a doctor for appropriate dosing.
Hepatic ImpairmentDose adjustment may be required in patients with impaired liver function. Consult a doctor for appropriate dosing.
Maximum Daily DoseThe maximum recommended daily dose for adults is 30 ml (providing 90 mg ambroxol and 600 mg guaifenesin) per day, but this must be confirmed by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Water
Drink plenty
Helps thin mucus and keeps you hydrated.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of amlice t syrup

✅ Common Side Effects

Nausea (Common (1-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (1-10%))
Take with food and stay hydrated. If vomiting is severe or persistent, contact your doctor.
Stomach discomfort or heartburn (Common (1-10%))
Take with meals. Avoid lying down immediately after taking the medicine.
Diarrhea (Common (1-10%))
Stay hydrated. If diarrhea is severe or lasts more than a few days, consult your doctor.
Drowsiness (Uncommon (0.1-1%))
Avoid driving or operating machinery until you know how this medicine affects you.
Headache (Uncommon (0.1-1%))
Usually resolves on its own. If it persists, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop the medicine and seek immediate medical help if you develop a painful rash, blisters, or peeling skin.
Bronchospasm (Rare (<0.1%))
Seek immediate medical attention if you experience sudden difficulty breathing or wheezing.

⚠️ Rare Side Effects

Severe abdominal pain
Seek immediate medical attention.
Blood in vomit or stool
Seek immediate medical attention.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Codeine Major
Dextromethorphan Major
Atropine Moderate
Scopolamine Moderate
Amoxicillin Moderate
Cefuroxime Moderate
Furosemide Moderate
Antacids Minor
Alcohol Moderate

🚨 Major Interactions

  • Cough suppressants (e.g., codeine, dextromethorphan)
  • Anticholinergic drugs (e.g., atropine, scopolamine)

⚡ Moderate Interactions

  • Antibiotics (e.g., amoxicillin, cefuroxime)
  • Diuretics (e.g., furosemide)

🍷 Alcohol Interaction

Alcohol may increase drowsiness and dizziness caused by this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy or hypersensitivity to ambroxol, guaifenesin, or any other ingredient in this medicine.","Children under 2 years of age.","Severe liver disease.","Severe kidney disease.","Use in patients with rare hereditary conditions such as fructose intolerance (due to sorbitol content in some formulations)."]

⚠️ Warnings & Precautions

["Do not use this medicine for a chronic cough or a cough that produces a lot of mucus without medical advice.","If your cough persists for more than 7 days, recurs, or is accompanied by fever, rash, or persistent headache, consult a doctor.","This medicine may cause drowsiness. Avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine.","Do not exceed the recommended dose.","Use with caution in patients with peptic ulcer disease.","Use with caution in patients with asthma or other respiratory conditions.","Consult your doctor before use if you are pregnant or breastfeeding."]

🤱 Lactation Safety

It is not known whether ambroxol and guaifenesin pass into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

If you suspect an overdose, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, diarrhea, and abdominal pain. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it more often than recommended. Shake the bottle well before each use to ensure the medicine is evenly mixed. Use a proper measuring device (such as a dosing cup or oral syringe) to measure the dose accurately; do not use a kitchen spoon. This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. Do not drink alcohol while taking this medicine, as it may increase drowsiness and stomach upset. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not use this medicine for a chronic cough or a cough that produces a lot of mucus without first talking to your doctor. Keep this medicine out of the reach of children. Store it at room temperature, away from direct sunlight and moisture. Do not use this medicine after the expiry date printed on the pack. If your symptoms do not improve within 7 days or if they worsen, stop taking this medicine and consult your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. They may also have reduced liver or kidney function, which can affect drug clearance. Dose adjustment may be necessary. Consult a doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. The safety of this medicine during pregnancy is not well established.

🏥 Post-Surgery Considerations

If you have recently had surgery, consult your doctor before using this medicine, as it may interact with other medications or affect recovery.

🦷 Dental Procedures

This medicine does not typically interfere with dental procedures. However, inform your dentist that you are taking it, especially if you are scheduled for surgery.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated by drinking plenty of fluids.
🥗
Use a humidifier to add moisture to the air.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Get plenty of rest to help your body recover.
🧘
Practice good hand hygiene to prevent infections.
🌞
Avoid irritants like dust and strong fumes.

🏋️ Exercise Considerations

While taking this medicine, you may feel drowsy or dizzy. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. Light activity like walking is generally safe if you feel up to it.

🥗 Diet Recommendations

Drink warm fluids like herbal tea or soup to soothe your throat.
Include foods rich in vitamin C to support your immune system.
Avoid cold drinks and ice cream which may worsen cough.
Eat a balanced diet to support recovery.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness in some people. If affected, avoid driving, operating machinery, or performing tasks that require mental alertness. It is usually safe to work if you do not experience these side effects, but use caution.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your cough persists for more than 7 days, if it worsens, or if you experience any severe side effects. Do not stop taking prescribed antibiotics or other medicines without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use may mask underlying conditions. If you need this medicine for more than 7 days, consult your doctor to determine the cause of your cough. Regular monitoring of liver and kidney function may be advised in patients with pre-existing disease.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Inhaling steam can help loosen mucus and soothe airways.

Evidence: Limited
Saline nasal irrigation

Helps clear nasal congestion and postnasal drip.

Evidence: Moderate
Honey

A spoonful of honey can soothe cough, but not for infants under 1 year.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are due for a vaccine, inform your healthcare provider that you are taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it at room temperature and protect it from direct sunlight. If you are crossing time zones, continue taking your doses at regular intervals as prescribed, but adjust timing gradually to local time. Do not leave it in a hot car or checked luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis
He was prescribed this medicine for a productive cough with thick mucus. After taking it as directed for 5 days, he noticed that his cough became more productive and his chest felt less congested. He took it with meals to avoid stomach upset.
💡 Lesson: Taking this medicine with food and staying hydrated can improve tolerability and effectiveness.
👤 A 60-year-old woman with COPD and chronic mucus
She used this medicine as part of her COPD management. It helped her clear mucus more easily, but she experienced mild nausea initially. Her doctor advised her to take it with food, which reduced the nausea.
💡 Lesson: Side effects like nausea can often be managed by taking the medicine with food.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 minutes to 1 hour after taking a dose. You may notice easier mucus clearance within a few hours.

Q: Can I take this medicine with antibiotics?

A: Yes, it is often taken with antibiotics, and in fact, ambroxol may enhance the effect of some antibiotics in the lungs. However, always inform your doctor about all medicines you are taking.

Q: Is this medicine safe for children?

A: This medicine is not recommended for children under 2 years. For older children, consult a pediatrician for appropriate dosing.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for amlice t syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: This medicine is only for productive cough with thick mucus. It is not effective for dry cough or cough due to other causes.
  • Myth: More medicine means faster relief.
    Fact: Taking more than the recommended dose can increase side effects without providing extra benefit.
  • Myth: It is safe to take this medicine with any other cough medicine.
    Fact: Combining with cough suppressants can be harmful. Always consult a doctor before combining medicines.

🔄 Alternative Options

Generic Alternatives

  • Ambroxol + Guaifenesin syrup (various manufacturers)

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Ambroxol + Guaifenesin)","composition":"Ambroxol 15mg/5ml + Guaifenesin 100mg/5ml","uses":"Productive cough","notes":"Combination mucolytic and expectorant"},{"medicine":"Ambroxol alone","composition":"Ambroxol 15mg/5ml","uses":"Productive cough","notes":"Mucolytic only"},{"medicine":"Guaifenesin alone","composition":"Guaifenesin 100mg/5ml","uses":"Productive cough","notes":"Expectorant only"}]

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