amitax 50mg injection

4.6 (14 reviews)

Amikacin (50mg)

🏭 Alkem Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is amitax 50mg injection used for?

Amikacin Sulphate 500mg Injection (Amikacin) is used to treat OPHTHAL. It contains Amikacin (50mg), which Binds to 30S ribosomal subunit, causing misreading of mRNA and inhibition of pro. Always consult your doctor before use. Take as prescribed.

Generic Name: Amikacin
Manufacturer: Alkem Laboratories Ltd
Form: Allopathy
Pregnancy Category: D
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 amitax 50mg injection Uses & Benefits

Serious Gram-negative infections (sepsis, pneumonia, complicated UTI, intra-abdominal infections); adjunct in tuberculosis; neonatal sepsis.

Off-label uses: Brucellosis, Plague, Tularemia

📋 Drug Information

Generic Name(s)	Amikacin
Brand Name	Amikacin Sulphate 500mg Injection
Manufacturer	Alkem Laboratories Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	OPHTHAL
Action Class	Aminoglycosides
Route of Administration	Intramuscular, Intravenous
Storage	Store at 20-25°C; protect from light; do not freeze.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after intramuscular injection; peak plasma concentrations achieved within 1 hour.

DistributionDistributes widely into extracellular fluids; high concentrations in urine, bile, and synovial fluid; crosses placenta; minimal penetration into cerebrospinal fluid unless meninges inflamed.

Protein Binding0-11%

MetabolismMinimal hepatic metabolism; primarily excreted unchanged.

Half-Life2-3 hours (normal renal function); up to 30-60 hours in renal impairment.

ExcretionRenal excretion (90-98% unchanged) via glomerular filtration.

Bioavailability100% (IM); not absorbed orally.

Onset of ActionRapid (within 1 hour for IM).

Peak Plasma Time1 hour (IM); end of infusion (IV).

Duration of Action8-12 hours (dose-dependent).

How It Works

Binds to 30S ribosomal subunit, causing misreading of mRNA and inhibition of protein synthesis.

Mechanism Steps

1Binds to 30S ribosomal subunit

2Interferes with initiation complex

3Causes misreading of mRNA codons

💡 How to Take amitax 50mg injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of amitax 50mg injection

✅ Common Side Effects

Nephrotoxicity
Ototoxicity (vestibular and cochlear)
Nausea
Vomiting
Rash

🚨 Serious Side Effects

Acute renal failure
Irreversible hearing loss
Neuromuscular blockade
Anaphylaxis

⚠️ Rare Side Effects

Superinfection
Clostridium difficile colitis
Hypomagnesemia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Neuromuscular blocking agents	Major	Enhanced neuromuscular blockade, respiratory depression
Cisplatin	Major	Increased nephrotoxicity and ototoxicity
Loop diuretics	Major	Increased ototoxicity
Vancomycin	Major	Increased nephrotoxicity
Penicillins	Moderate	Synergistic antibacterial effect
NSAIDs	Moderate	Increased nephrotoxicity risk

🚨 Major Interactions

Neuromuscular blocking agents
Other aminoglycosides
Cisplatin
Loop diuretics
Vancomycin

⚡ Moderate Interactions

Penicillins (synergy)
Cephalosporins
NSAIDs
Methoxyflurane

ℹ️ Minor Interactions

Dimercaprol
Indomethacin

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to amikacin or other aminoglycosides; myasthenia gravis; pre-existing severe renal impairment.

📊 Monitoring Parameters

Renal function (serum creatinine, BUN), urine output, audiometry, serum drug levels (peak and trough).

🤱 Lactation Safety

Caution; small amounts excreted in breast milk; monitor infant for diarrhea, candidiasis.

💊 Overdose Management

Supportive care; hemodialysis may enhance elimination; monitor renal function and hearing.

⏰ Missed Dose

Administer as soon as remembered; if near next dose, skip missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for amitax 50mg injection

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Alternative brands with exact same active ingredient (Amikacin (50mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

amitax 50mg injection

What is amitax 50mg injection used for?

💊 amitax 50mg injection Uses & Benefits

📋 Drug Information

🔬 Pharmacology (PK/PD)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take amitax 50mg injection

⚠️ Side Effects of amitax 50mg injection

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

ℹ️ Minor Interactions

🍽️ Food Interactions

🍷 Alcohol Interaction

🛡️ Safety & Warnings

🚫 Contraindications

📊 Monitoring Parameters

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

🔄 Substitutes for amitax 50mg injection

⭐ User Reviews

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