Amislan 250mg Injection - Uses, Price, Side Effects
What is amislan 250mg injection used for?
Amislan 250mg Injection contains Amikacin, an aminoglycoside antibiotic that treats severe bacterial infections by inhibiting bacterial protein synthesis. It is used for infections of the respiratory tract, urinary tract, skin, bones, and septicemia. Administered intramuscularly or intravenously under medical supervision.
- Generic Name: Amikacin
- Manufacturer: Slaney Healthcare
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ amislan 250mg injection Uses & Benefits
Serious Gram-negative infections (sepsis, pneumonia, complicated UTI, intra-abdominal infections); adjunct in tuberculosis; neonatal sepsis.
Off-label uses: Brucellosis, Plague, Tularemia
๐ Drug Information
| Generic Name(s) | Amikacin |
| Brand Name | Amikacin Sulphate 500mg Injection |
| Manufacturer | Slaney Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Aminoglycosides |
| Route of Administration | Intramuscular, Intravenous |
| Storage | Store at 20-25ยฐC; protect from light; do not freeze. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Binds to 30S ribosomal subunit, causing misreading of mRNA and inhibition of protein synthesis.
Mechanism Steps
๐ก How to Take amislan 250mg injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of amislan 250mg injection
โ Common Side Effects
- Nephrotoxicity
- Ototoxicity (vestibular and cochlear)
- Nausea
- Vomiting
- Rash
๐จ Serious Side Effects
- Acute renal failure
- Irreversible hearing loss
- Neuromuscular blockade
- Anaphylaxis
โ ๏ธ Rare Side Effects
- Superinfection
- Clostridium difficile colitis
- Hypomagnesemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Furosemide | Moderate | Increased nephrotoxicity |
| Cisplatin | Major | Increased nephrotoxicity and ototoxicity |
๐จ Major Interactions
- Neuromuscular blocking agents
- Other aminoglycosides
- Cisplatin
- Loop diuretics
- Vancomycin
โก Moderate Interactions
- Penicillins (synergy)
- Cephalosporins
- NSAIDs
- Methoxyflurane
โน๏ธ Minor Interactions
- Dimercaprol
- Indomethacin
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to amikacin or other aminoglycosides; myasthenia gravis; pre-existing severe renal impairment.
๐ Monitoring Parameters
Renal function (serum creatinine, BUN), urine output, audiometry, serum drug levels (peak and trough).
๐คฑ Lactation Safety
Caution; small amounts excreted in breast milk; monitor infant for diarrhea, candidiasis.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination; monitor renal function and hearing.
โฐ Missed Dose
Administer as soon as remembered; if near next dose, skip missed dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for amislan 250mg injection
View AllAlternative brands with exact same active ingredient (Amikacin (250mg)):
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amipic 250mg injectionPCI Pharmaceuticals โน6.87 80.4% CHEAPER
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amisac 250mg injectionShreya Life Sciences Pvt Ltd โน7.62 78.2% CHEAPER
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amikop 250mg injectionKopran Ltd โน8.00 77.1% CHEAPER
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cachmik 250mg injectionCachet Pharmaceuticals Pvt Ltd โน8.18 76.6% CHEAPER
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akasyn 250mg injectionGlenmark Pharmaceuticals Ltd โน9.37 73.2% CHEAPER
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amilab 250mg injectionLaborate Pharmaceuticals India Ltd โน9.55 72.7% CHEAPER
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amicip 250mg injectionCipla Ltd โน9.56 72.7% CHEAPER
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amee 250mg injectionZydus Healthcare Limited โน10.00 71.4% CHEAPER
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lupamik 250mg injectionLupin Ltd โน10.50 70% CHEAPER
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zekacin 250mg injectionWockhardt Ltd โน10.93 68.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.