ameto p 30 mg/500 mg tablet - Uses, Price, Side Effects & Substitutes
What is ameto p 30 mg/500 mg tablet used for?
Asoformin P 15mg/500mg Tablet (Pioglitazone + Metformin) is used to treat ANTI DIABETIC. It contains Pioglitazone (30mg) + Metformin (500mg), which Pioglitazone: PPARΞ³ agonist; Metformin: AMPK activation. Always consult your doctor before use. Take as prescribed.
- Generic Name: Pioglitazone + Metformin
- Manufacturer: Salud Care India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
π ameto p 30 mg/500 mg tablet Uses & Benefits
Type 2 diabetes mellitus as adjunct to diet and exercise
Off-label uses: Polycystic ovary syndrome (Metformin component)
π Drug Information
| Generic Name(s) | Pioglitazone + Metformin |
| Brand Name | Asoformin P 15mg/500mg Tablet |
| Manufacturer | Salud Care India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Thiazolidinedione + Biguanide |
| Route of Administration | Oral |
| Storage | Store at 20-25Β°C, protect from light and moisture |
| Shelf Life | As per manufacturer |
π¬ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Pioglitazone: PPARΞ³ agonist; Metformin: AMPK activation
Mechanism Steps
π‘ How to Take ameto p 30 mg/500 mg tablet
Follow your doctor's prescription exactly.
β οΈ Side Effects of ameto p 30 mg/500 mg tablet
β Common Side Effects
- Hypoglycemia
- Weight gain
- Edema
- Gastrointestinal upset
- Diarrhea
π¨ Serious Side Effects
- Lactic acidosis
- Heart failure
- Hepatotoxicity
- Bladder cancer (Pioglitazone)
β οΈ Rare Side Effects
- Macular edema
- Bone fractures
- Vitamin B12 deficiency
Consult your doctor if you experience any unusual symptoms.
π¬ Drug Interactions
| β οΈ Drug | Severity | Effect |
|---|---|---|
| Insulin | Major | Increased risk of hypoglycemia |
| Sulfonylureas | Major | Additive hypoglycemic effect |
| Gemfibrozil | Major | Increased pioglitazone exposure |
| Rifampin | Major | Decreased pioglitazone efficacy |
| NSAIDs | Moderate | Reduced metformin efficacy |
| Diuretics | Moderate | Risk of lactic acidosis |
| ACE inhibitors | Moderate | Enhanced hypoglycemic effect |
| Corticosteroids | Moderate | Hyperglycemia |
| Calcium channel blockers | Minor | Possible interaction |
| Oral contraceptives | Minor | Possible reduced efficacy |
π¨ Major Interactions
- Insulin
- Sulfonylureas
- CYP2C8 inhibitors (gemfibrozil)
- CYP2C8 inducers (rifampin)
β‘ Moderate Interactions
- NSAIDs
- Diuretics
- ACE inhibitors
- Corticosteroids
βΉοΈ Minor Interactions
- Calcium channel blockers
- Oral contraceptives
π½οΈ Food Interactions
Metformin: Food decreases absorption; Pioglitazone: Food delays absorption
π· Alcohol Interaction
Increased risk of lactic acidosis with Metformin
π‘οΈ Safety & Warnings
π« Contraindications
Renal impairment (eGFR <30), hepatic impairment, heart failure (NYHA III/IV), diabetic ketoacidosis, hypersensitivity
π Monitoring Parameters
Blood glucose, HbA1c, renal function, liver function, signs of heart failure
π€± Lactation Safety
Not recommended; Metformin excreted in milk, Pioglitazone unknown
π Overdose Management
Supportive care; monitor blood glucose; Metformin: consider hemodialysis
β° Missed Dose
Take as soon as remembered unless near next dose; do not double dose