ambulax etm tablet - Uses, Price, Side Effects & Substitutes
What is ambulax etm tablet used for?
Ambulax-ET Tablet (Etizolam + Propranolol) is used to treat NEURO CNS. It contains Etizolam (0.25mg) + Propranolol (20mg), which Etizolam enhances GABA-A receptor activity; Propranolol blocks beta-adrenergic r. Always consult your doctor before use. Take as prescribed.
- Generic Name: Etizolam + Propranolol
- Manufacturer: Unimarck Pharma India Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ ambulax etm tablet Uses & Benefits
Anxiety disorders, panic attacks, essential tremor, performance anxiety, adjunct in hypertension
Off-label uses: Insomnia, migraine prophylaxis, hyperthyroidism symptoms
๐ Drug Information
| Generic Name(s) | Etizolam + Propranolol |
| Brand Name | Ambulax-ET Tablet |
| Manufacturer | Unimarck Pharma India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Benzodiazepine + Beta-blocker |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Etizolam enhances GABA-A receptor activity; Propranolol blocks beta-adrenergic receptors
Mechanism Steps
๐ก How to Take ambulax etm tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of ambulax etm tablet
โ Common Side Effects
- Drowsiness
- Dizziness
- Fatigue
- Dry mouth
- Nausea
- Bradycardia
- Hypotension
- Cold extremities
๐จ Serious Side Effects
- Respiratory depression
- Severe bradycardia
- Heart block
- Hypotension
- Hepatic injury
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Hallucinations
- Paradoxical excitement
- Bronchospasm
- Raynaud's phenomenon
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| CNS depressants | Major | Enhanced sedation and respiratory depression |
| CYP3A4 inhibitors | Major | Increased etizolam levels and toxicity |
| CYP2D6 inhibitors | Major | Increased propranolol levels and bradycardia |
| Calcium channel blockers | Major | Additive hypotensive effect |
| Antiarrhythmics | Major | Increased risk of bradycardia and heart block |
| Oral hypoglycemics | Moderate | Masking of hypoglycemic symptoms |
| Theophylline | Moderate | Antagonism of bronchodilator effect |
| Warfarin | Moderate | Increased INR and bleeding risk |
| Digoxin | Moderate | Increased risk of bradycardia |
| Antacids | Minor | Reduced absorption of etizolam |
| Caffeine | Minor | Reduced anxiolytic effect |
| Smoking | Minor | Increased metabolism of propranolol |
๐จ Major Interactions
- CNS depressants
- CYP3A4 inhibitors
- CYP2D6 inhibitors
- Calcium channel blockers
- Antiarrhythmics
โก Moderate Interactions
- Oral hypoglycemics
- Theophylline
- Warfarin
- Digoxin
โน๏ธ Minor Interactions
- Antacids
- Caffeine
- Smoking
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase etizolam levels, High-protein meals may decrease propranolol absorption
๐ท Alcohol Interaction
Avoid alcohol; increased CNS depression and hypotension risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, bronchial asthma, COPD, sinus bradycardia, heart block, cardiogenic shock, myasthenia gravis, narrow-angle glaucoma, severe hepatic impairment
๐ Monitoring Parameters
Heart rate, blood pressure, respiratory rate, liver function, renal function, signs of CNS depression
๐คฑ Lactation Safety
Not recommended; both drugs excreted in breast milk
๐ Overdose Management
Supportive care; flumazenil for etizolam overdose; atropine for bradycardia; glucagon for propranolol overdose
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose