am dopa 500mg tablet - Methyldopa (500mg) medicine

am dopa 500mg tablet

4.5 (13 reviews)
๐Ÿญ Dahlia Pharmaceutical Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is am dopa 500mg tablet used for?

Alphadopa (Methyldopa) is used to treat CARDIAC. It contains Methyldopa (500mg), which Stimulates central alpha-2 adrenergic receptors, reducing sympathetic outflow fr. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Methyldopa
  • Manufacturer: Dahlia Pharmaceutical Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š am dopa 500mg tablet Uses & Benefits

Hypertension (especially in pregnancy); hypertensive crisis.

Off-label uses: Management of withdrawal symptoms in opioid dependence (limited evidence).

๐Ÿ“‹ Drug Information

Generic Name(s)Methyldopa
Brand NameAlphadopa
ManufacturerDahlia Pharmaceutical Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAlpha 2-adrenoceptors agonist (Central sympatholytics)
Route of AdministrationOral.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed from gastrointestinal tract; peak plasma concentration occurs 2-4 hours after oral administration.
DistributionCrosses the blood-brain barrier and placenta; distributed into breast milk.
Protein BindingLess than 15% bound to plasma proteins.
MetabolismExtensively metabolized in the liver; active metabolite is alpha-methylnorepinephrine.
Half-LifeApproximately 2 hours (normal renal function); prolonged in renal impairment.
ExcretionPrimarily excreted in urine as unchanged drug and metabolites.
BioavailabilityApproximately 50% (oral).
Onset of Action3-6 hours after oral dose.
Peak Plasma Time2-4 hours.
Duration of Action12-24 hours.

How It Works

Stimulates central alpha-2 adrenergic receptors, reducing sympathetic outflow from the brainstem, leading to decreased peripheral vascular resistance and blood pressure.

Mechanism Steps

1Methyldopa is converted to alpha-methylnorepinephrine in the central nervous system.
2Alpha-methylnorepinephrine stimulates central alpha-2 adrenergic receptors.
3Stimulation of alpha-2 receptors reduces sympathetic outflow from the vasomotor center.

๐Ÿ’ก How to Take am dopa 500mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of am dopa 500mg tablet

โœ… Common Side Effects

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Headache
  • Nasal congestion

๐Ÿšจ Serious Side Effects

  • Hemolytic anemia
  • Hepatotoxicity
  • Parkinsonism
  • Psychiatric disturbances

โš ๏ธ Rare Side Effects

  • Lupus-like syndrome
  • Gynecomastia
  • Leukopenia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAO inhibitors Major Hypertensive crisis
Lithium Major Increased lithium toxicity
Levodopa Major Reduced antiparkinsonian effect
Beta-blockers Moderate Additive bradycardia
Anesthetics Moderate Enhanced hypotensive effect
Iron supplements Minor Decreased methyldopa absorption

๐Ÿšจ Major Interactions

  • MAO inhibitors
  • Lithium
  • Levodopa

โšก Moderate Interactions

  • Antihypertensives
  • Beta-blockers
  • Anesthetics

โ„น๏ธ Minor Interactions

  • Iron supplements
  • Tricyclic antidepressants

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

May enhance hypotensive effect; avoid excessive alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to methyldopa; active hepatic disease; MAO inhibitor therapy.

๐Ÿ“Š Monitoring Parameters

Blood pressure; liver function tests; CBC; Coombs test (if on prolonged therapy).

๐Ÿคฑ Lactation Safety

Limited data; use with caution; excreted in breast milk.

๐Ÿ’Š Overdose Management

Gastric lavage; supportive measures; atropine for bradycardia; vasopressors for hypotension.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for am dopa 500mg tablet

View All

Alternative brands with exact same active ingredient (Methyldopa (500mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

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