alzocept-5 m tablet - Donepezil (5mg) + Memantine (10mg) medicine

Alzocept-5 M Tablet - Uses, Price, Side Effects

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๐Ÿญ Lifecare Neuro Products Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is alzocept-5 m tablet used for?

Alzocept-5 M Tablet is a combination of Donepezil (5mg) and Memantine (10mg) used to treat moderate to severe Alzheimer's disease. Donepezil increases acetylcholine levels to improve cognition, while Memantine regulates glutamate to protect nerve cells. Together, they help slow symptom progression and improve daily function.

  • Generic Name: Donepezil + Memantine
  • Manufacturer: Lifecare Neuro Products Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š alzocept-5 m tablet Uses & Benefits

Alzheimer's disease (moderate to severe), Dementia associated with Parkinson's disease (off-label)

Off-label uses: Vascular dementia, Dementia with Lewy bodies, Mild cognitive impairment

๐Ÿ“‹ Drug Information

Generic Name(s)Donepezil + Memantine
Brand NameAlzil-M 5 Tablet
ManufacturerLifecare Neuro Products Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassCholinesterase inhibitor + NMDA receptor antagonist
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionDonepezil: Well absorbed orally, peak plasma concentration in 3-4 hours; Memantine: Rapidly and completely absorbed, peak plasma concentration in 3-8 hours.
DistributionDonepezil: Volume of distribution ~12 L/kg, crosses blood-brain barrier; Memantine: Volume of distribution ~10 L/kg, crosses blood-brain barrier.
Protein BindingDonepezil: ~96% bound to plasma proteins; Memantine: ~45% bound.
MetabolismDonepezil: Metabolized by CYP3A4 and CYP2D6; Memantine: Minimal hepatic metabolism, primarily excreted unchanged.
Half-LifeDonepezil: ~70 hours; Memantine: ~60-80 hours.
ExcretionDonepezil: Renal (57%) and fecal (15%); Memantine: Renal (75-90% unchanged).
BioavailabilityDonepezil: ~100%; Memantine: ~100%.
Onset of ActionDonepezil: 2-4 weeks; Memantine: 2-4 weeks.
Peak Plasma TimeDonepezil: 3-4 hours; Memantine: 3-8 hours.
Duration of ActionDonepezil: 24 hours; Memantine: 24 hours.

How It Works

Donepezil inhibits acetylcholinesterase, increasing acetylcholine levels; Memantine is an NMDA receptor antagonist, reducing glutamate excitotoxicity.

Mechanism Steps

1Donepezil reversibly inhibits acetylcholinesterase, increasing acetylcholine in synaptic clefts.
2Enhanced cholinergic neurotransmission improves cognitive function.
3Memantine non-competitively blocks NMDA receptors, reducing glutamate-mediated excitotoxicity.

๐Ÿ’ก How to Take alzocept-5 m tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of alzocept-5 m tablet

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Insomnia
  • Fatigue
  • Muscle cramps
  • Headache
  • Dizziness
  • Confusion

๐Ÿšจ Serious Side Effects

  • Bradycardia
  • Heart block
  • Seizures
  • GI bleeding
  • Neuroleptic malignant syndrome (rare)

โš ๏ธ Rare Side Effects

  • Hepatitis
  • Pancreatitis
  • Rhabdomyolysis
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Anticholinergics Moderate May reduce efficacy of Donepezil
NMDA antagonists Moderate Increased risk of adverse effects
NSAIDs Moderate Increased risk of gastrointestinal bleeding

๐Ÿšจ Major Interactions

  • Anticholinergics
  • Succinylcholine
  • NMDA antagonists (e.g., amantadine, ketamine)
  • CYP3A4 inducers/inhibitors (for donepezil)

โšก Moderate Interactions

  • NSAIDs
  • Antipsychotics
  • Cholinergic agonists
  • CYP2D6 inhibitors

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Quinidine

๐Ÿฝ๏ธ Food Interactions

High-fat meals may delay absorption of donepezil

๐Ÿท Alcohol Interaction

Avoid alcohol; may worsen CNS effects.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to donepezil, memantine, or piperidine derivatives, Severe hepatic impairment

๐Ÿ“Š Monitoring Parameters

Cognitive function, GI symptoms, Heart rate, Weight, Renal function

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk.

๐Ÿ’Š Overdose Management

Supportive care; activated charcoal if recent ingestion; monitor for cholinergic crisis (donepezil) or CNS depression (memantine).

โฐ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

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