Alrzin-M Tablet - Uses, Price, Side Effects
What is alrzin-m tablet used for?
Alrzin-M Tablet is a combination of Levocetirizine (5mg) and Montelukast (10mg) used to treat allergic rhinitis and asthma. Levocetirizine blocks histamine to reduce sneezing and runny nose, while Montelukast blocks leukotrienes to prevent airway inflammation and bronchoconstriction. It provides relief from seasonal allergies and helps control asthma symptoms.
- Generic Name: Levocetirizine + Montelukast
- Manufacturer: Vinsha Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ alrzin-m tablet Uses & Benefits
Seasonal and perennial allergic rhinitis; asthma prophylaxis
Off-label uses: Urticaria, Eosinophilic esophagitis
๐ Drug Information
| Generic Name(s) | Levocetirizine + Montelukast |
| Brand Name | Allercet-M Tablet |
| Manufacturer | Vinsha Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Leukotriene Receptor Antagonist |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Levocetirizine selectively inhibits peripheral H1 receptors; Montelukast antagonizes leukotriene D4 at CysLT1 receptors
Mechanism Steps
๐ก How to Take alrzin-m tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of alrzin-m tablet
โ Common Side Effects
- Headache
- Drowsiness
- Dry mouth
- Cough
- Pharyngitis
๐จ Serious Side Effects
- Angioedema
- Anaphylaxis
- Neuropsychiatric events (agitation, depression)
โ ๏ธ Rare Side Effects
- Hepatitis
- Thrombocytopenia
- Seizures
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | Increased risk of bleeding |
| Ketoconazole | Moderate | Increased levocetirizine levels |
| Phenytoin | Moderate | Decreased montelukast efficacy |
๐จ Major Interactions
- CYP3A4 inducers (e.g., Rifampin)
- CYP2C9 inducers (e.g., Phenobarbital)
โก Moderate Interactions
- Gemfibrozil
- Itraconazole
- Warfarin
โน๏ธ Minor Interactions
- Theophylline
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Montelukast absorption decreased by high-fat meal; take on empty stomach
๐ท Alcohol Interaction
Levocetirizine may potentiate CNS depression
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component; severe renal impairment (CrCl <10 mL/min) for levocetirizine
๐ Monitoring Parameters
Renal function, hepatic function, signs of neuropsychiatric events
๐คฑ Lactation Safety
Levocetirizine excreted in breast milk; caution advised
๐ Overdose Management
Symptomatic and supportive; no specific antidote
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double