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aloypion 300mg tablet - Bupropion (300mg) medicine

aloypion 300mg tablet - Uses, Price, Side Effects & Substitutes

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Bupropion (300mg)
๐Ÿญ Enrico Pharmaceuticals ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 27, 2026

What is aloypion 300mg tablet used for?

Atydep 150mg Tablet SR (Bupropion) is used to treat NEURO CNS. It contains Bupropion (300mg), which Weak inhibitor of neuronal reuptake of norepinephrine and dopamine; does not inh. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Bupropion
  • Manufacturer: Enrico Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š aloypion 300mg tablet Uses & Benefits

Major depressive disorder, seasonal affective disorder, smoking cessation.

Off-label uses: ADHD, bipolar depression, sexual dysfunction, obesity, neuropathic pain.

๐Ÿ“‹ Drug Information

Generic Name(s)Bupropion
Brand NameAtydep 150mg Tablet SR
ManufacturerEnrico Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassNorepinephrine-dopamine reuptake inhibitor (NDRI)
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; peak plasma concentrations occur within 3 hours for immediate-release, but sustained-release formulation has slower absorption.
DistributionDistributed widely; crosses blood-brain barrier; volume of distribution approximately 20-30 L/kg.
Protein Binding82-88% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via CYP2B6 to active metabolites (hydroxybupropion, threohydrobupropion, erythrohydrobupropion).
Half-LifeApproximately 21 hours for bupropion; 20-24 hours for hydroxybupropion.
ExcretionPrimarily renal (87%) as metabolites; 10% in feces.
BioavailabilityApproximately 80% for sustained-release formulation.
Onset of ActionTherapeutic effects may take 2-4 weeks; immediate effects on norepinephrine and dopamine reuptake oc
Peak Plasma Time3 hours for sustained-release formulation.
Duration of ActionSustained-release formulation provides therapeutic levels for 12-24 hours.

How It Works

Weak inhibitor of neuronal reuptake of norepinephrine and dopamine; does not inhibit serotonin reuptake or monoamine oxidase.

Mechanism Steps

1Bupropion binds to and inhibits the norepinephrine transporter (NET) and dopamine transporter (DAT) on presynaptic neurons.
2Inhibition of NET and DAT prevents reuptake of norepinephrine and dopamine into the presynaptic neuron.
3Increased extracellular concentrations of norepinephrine and dopamine in the synaptic cleft.

๐Ÿ’ก How to Take aloypion 300mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of aloypion 300mg tablet

โœ… Common Side Effects

  • Dry mouth
  • Insomnia
  • Headache
  • Nausea
  • Constipation
  • Dizziness
  • Sweating
  • Tremor
  • Anxiety
  • Agitation

๐Ÿšจ Serious Side Effects

  • Seizures
  • Hypertension
  • Tachycardia
  • Allergic reactions (rash, urticaria, angioedema)
  • Psychiatric symptoms (hallucinations, paranoia, confusion)
  • Suicidal thoughts or behavior

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Stevens-Johnson syndrome
  • Serotonin syndrome
  • Cardiac arrhythmias
  • Parkinsonism
  • Dyskinesia
  • Akathisia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Increased risk of hypertensive crisis
Selegiline Major Increased risk of serotonin syndrome
Linezolid Major Increased risk of serotonin syndrome
Methylene blue Major Increased risk of serotonin syndrome
Ritonavir Major Increased bupropion levels, toxicity
Lopinavir Major Increased bupropion levels, toxicity
Efavirenz Major Decreased bupropion levels, reduced efficacy
Carbamazepine Major Decreased bupropion levels, reduced efficacy
Phenobarbital Major Decreased bupropion levels, reduced efficacy
Phenytoin Major Decreased bupropion levels, reduced efficacy
Cimetidine Moderate Increased bupropion levels
Clopidogrel Moderate Increased bupropion levels
Orphenadrine Moderate Increased bupropion levels
Thiotepa Moderate Increased bupropion levels
Cyclophosphamide Moderate Increased bupropion levels
Tamoxifen Moderate Decreased bupropion levels
Citalopram Moderate Increased risk of seizures
Sertraline Moderate Increased risk of seizures
Fluoxetine Moderate Increased risk of seizures
Paroxetine Moderate Increased risk of seizures
Duloxetine Moderate Increased risk of seizures
Venlafaxine Moderate Increased risk of seizures
Amitriptyline Moderate Increased risk of seizures
Imipramine Moderate Increased risk of seizures
Nortriptyline Moderate Increased risk of seizures
Haloperidol Moderate Increased risk of seizures
Risperidone Moderate Increased risk of seizures
Olanzapine Moderate Increased risk of seizures
Clozapine Moderate Increased risk of seizures
Levodopa Moderate Increased risk of adverse effects
Amantadine Moderate Increased risk of adverse effects
Nicotine Moderate Increased blood pressure
Alcohol Moderate Increased risk of seizures and adverse effects
Caffeine Minor Increased stimulant effects
Theophylline Minor Increased stimulant effects
Warfarin Minor Possible altered anticoagulation
Digoxin Minor Possible altered digoxin levels
Beta-blockers Minor Possible increased blood pressure
ACE inhibitors Minor Possible increased blood pressure
Diuretics Minor Possible increased blood pressure

๐Ÿšจ Major Interactions

  • MAOIs
  • Selegiline
  • Linezolid
  • Methylene blue
  • Ritonavir
  • Lopinavir
  • Efavirenz
  • Carbamazepine
  • Phenobarbital
  • Phenytoin

โšก Moderate Interactions

  • Cimetidine
  • Clopidogrel
  • Orphenadrine
  • Thiotepa
  • Cyclophosphamide
  • Tamoxifen
  • Citalopram
  • Sertraline
  • Fluoxetine
  • Paroxetine
  • Duloxetine
  • Venlafaxine
  • Amitriptyline
  • Imipramine
  • Nortriptyline
  • Haloperidol
  • Risperidone
  • Olanzapine
  • Clozapine
  • Levodopa
  • Amantadine
  • Nicotine
  • Alcohol

โ„น๏ธ Minor Interactions

  • Caffeine
  • Theophylline
  • Warfarin
  • Digoxin
  • Beta-blockers
  • ACE inhibitors
  • Diuretics

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption; high-fat meal may increase peak concentration.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase risk of seizures and adverse effects.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Seizure disorder, current or prior diagnosis of bulimia or anorexia nervosa, abrupt discontinuation of alcohol or sedatives, MAOI use within 14 days, known hypersensitivity.

๐Ÿ“Š Monitoring Parameters

Blood pressure, heart rate, mood changes, suicidal ideation, weight, seizure activity.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution; monitor infant for agitation, poor feeding, and weight ga

๐Ÿ’Š Overdose Management

Activated charcoal, supportive care; monitor for seizures, cardiac arrhythmias; no specific antidote.

โฐ Missed Dose

If missed, take as soon as remembered unless close to next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for aloypion 300mg tablet

View All

Alternative brands with exact same active ingredient (Bupropion (300mg)):

Medical Note: Always consult your doctor before switching medications.

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