alopram 0.5mg/10mg tablet - Clonazepam (0.5mg) + Escitalopram Oxalate (10mg) medicine

Alopram 0.5mg/10mg Tablet - Uses, Price, Side Effects

4.2 (14 reviews)
๐Ÿญ Mediarka Lifesciences Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is alopram 0.5mg/10mg tablet used for?

Alopram 0.5mg/10mg Tablet is a combination of Clonazepam and Escitalopram used to treat anxiety disorders and depression. Clonazepam works by enhancing GABA activity to reduce anxiety, while Escitalopram increases serotonin levels to improve mood. It is typically taken once or twice daily as prescribed.

  • Generic Name: Clonazepam + Escitalopram
  • Manufacturer: Mediarka Lifesciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š alopram 0.5mg/10mg tablet Uses & Benefits

Generalized anxiety disorder, panic disorder, depression with anxiety

Off-label uses: Social anxiety disorder, post-traumatic stress disorder, insomnia

๐Ÿ“‹ Drug Information

Generic Name(s)Clonazepam + Escitalopram
Brand NameAsiclopam Tablet
ManufacturerMediarka Lifesciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassBenzodiazepine + SSRI
Route of AdministrationOral
StorageStore at 20-25ยฐC, protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionClonazepam: Well absorbed orally; Escitalopram: Well absorbed orally, food delays absorption
DistributionClonazepam: Highly lipophilic, crosses BBB; Escitalopram: Vd ~12-26 L/kg
Protein BindingClonazepam: ~85%; Escitalopram: ~56%
MetabolismClonazepam: Hepatic via CYP3A4; Escitalopram: Hepatic via CYP2C19, CYP3A4, CYP2D6
Half-LifeClonazepam: 30-40 hours; Escitalopram: 27-32 hours
ExcretionClonazepam: Urine (<2% unchanged); Escitalopram: Urine (8% unchanged) and feces
BioavailabilityClonazepam: ~90%; Escitalopram: ~80%
Onset of ActionClonazepam: 20-60 min; Escitalopram: 1-2 weeks (therapeutic)
Peak Plasma TimeClonazepam: 1-4 hours; Escitalopram: 5 hours
Duration of ActionClonazepam: 6-12 hours; Escitalopram: 24 hours

How It Works

Clonazepam: Enhances GABA-A receptor activity; Escitalopram: Inhibits serotonin reuptake

Mechanism Steps

1Clonazepam binds to GABA-A receptor benzodiazepine site
2Enhances GABA affinity, increasing chloride ion influx
3Hyperpolarizes neurons, reducing excitability

๐Ÿ’ก How to Take alopram 0.5mg/10mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of alopram 0.5mg/10mg tablet

โœ… Common Side Effects

  • Drowsiness
  • Dizziness
  • Fatigue
  • Nausea
  • Dry mouth
  • Constipation

๐Ÿšจ Serious Side Effects

  • Respiratory depression
  • Serotonin syndrome
  • QT prolongation
  • Suicidal thoughts
  • Seizures

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Hepatotoxicity
  • Stevens-Johnson syndrome
  • Paradoxical reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Increased risk of serotonin syndrome
CNS Depressants Major Enhanced sedation and respiratory depression
Warfarin Moderate Increased bleeding risk
Ketoconazole Moderate Increased clonazepam levels

๐Ÿšจ Major Interactions

  • MAOIs
  • CYP2C19 inhibitors
  • CYP3A4 inhibitors
  • Other CNS depressants

โšก Moderate Interactions

  • SSRIs/SNRIs
  • Antipsychotics
  • Lithium
  • Warfarin

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Oral contraceptives
  • Grapefruit juice

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase escitalopram levels; food delays absorption

๐Ÿท Alcohol Interaction

Avoid alcohol; increased CNS depression

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, severe hepatic impairment, narrow-angle glaucoma, MAOI use, respiratory depression

๐Ÿ“Š Monitoring Parameters

Liver function, renal function, ECG, suicidal ideation, sedation level

๐Ÿคฑ Lactation Safety

Not recommended; both drugs excreted in breast milk

๐Ÿ’Š Overdose Management

Supportive care, flumazenil for clonazepam overdose, ECG monitoring for QT prolongation

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

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