alo cef 200mg/200mg tablet - Cefixime (200mg) + Ofloxacin (200mg) medicine

Abixim O Tablet: Comprehensive Medicine Guide

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🏭 Allpa India Medicines Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
🤰 Pregnancy Category Not established from the available information. Both cefixime and ofloxacin are generally avoided during pregnancy unless the potential benefit justifies the potential risk. Consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Bloody or severe diarrhea
  • Tendon pain or swelling
  • Numbness or tingling in hands or feet
  • Seizures or severe dizziness
  • Decreased urine output
  • Yellowing of eyes or skin

If experiencing severe symptoms, call emergency services immediately.

What is alo cef 200mg/200mg tablet used for?

This medicine is a combination antibiotic containing cefixime and ofloxacin, used to treat various bacterial infections. It works by killing bacteria through two different mechanisms. It is available by prescription only and should be taken exactly as directed by a doctor.

  • Generic Name: Cefixime + Ofloxacin
  • Manufacturer: Allpa India Medicines Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alo cef 200mg/200mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सेफिक्सिम और ऑफ़्लोक्सासिन का संयोजन है, जिसका उपयोग विभिन्न जीवाणु संक्रमणों के इलाज के लिए किया जाता है। यह मूत्र मार्ग संक्रमण, श्वसन तंत्र संक्रमण, त्वचा संक्रमण और टाइफाइड बुखार के इलाज में प्रभावी है। यह दवा केवल डॉक्टर के पर्चे पर ही लेनी चाहिए और पूरा कोर्स पूरा करना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, दस्त, पेट दर्द, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, टेंडन टूटना, तंत्रिका क्षति और दौरे पड़ना शामिल हो सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक न छोड़ें और कोर्स पूरा करें। इसे भोजन के साथ लें। शराब से बचें। पर्याप्त पानी पिएं। एंटासिड, आयरन या जिंक सप्लीमेंट के साथ 2 घंटे का अंतराल रखें। गर्भवती और स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 alo cef 200mg/200mg tablet Uses & Benefits

[{"condition":"Urinary tract infections","description":"Used to treat complicated and uncomplicated urinary tract infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"Effective against bacterial bronchitis and pneumonia when caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Prescribed for bacterial skin infections such as cellulitis and abscesses.","evidence":"Well-established"},{"condition":"Typhoid fever","description":"Used in some regions for treating typhoid fever caused by Salmonella typhi.","evidence":"Established"},{"condition":"Gonorrhea","description":"May be used as an alternative treatment for uncomplicated gonorrhea.","evidence":"Limited"}]

Off-label uses: [{"condition":"Prostatitis","description":"Sometimes prescribed for chronic bacterial prostatitis, though not a first-line option.","evidence":"Limited"},{"condition":"Traveler's diarrhea","description":"Occasionally used for severe traveler's diarrhea caused by susceptible bacteria.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Urinary tract infections, Respiratory tract infections, Skin infections, Typhoid fever

📋 Drug Information

Generic Name(s)Cefixime + Ofloxacin
Brand NameAbixim O Tablet
ManufacturerAllpa India Medicines Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAntibiotic (Cephalosporin + Fluoroquinolone)
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf LifeTypically 24 months from the date of manufacture. Refer to the packaging for the exact expiry date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this combination only when clearly indicated to avoid unnecessary antibiotic exposure.
2
Advise patients to take the medicine with food to enhance absorption and reduce GI upset.
3
Warn patients about the risk of tendon rupture and to report any tendon pain immediately.
4
Monitor renal function periodically, especially in elderly patients.
5
Educate patients on the importance of completing the full course to prevent resistance.
6
Caution patients to avoid alcohol and excessive sunlight during treatment.
7
Consider alternative antibiotics in patients with a history of fluoroquinolone-related adverse effects.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Urinary tract infection
This medicine is commonly prescribed for this.
Likely Use
Respiratory tract infection
This medicine is commonly prescribed for this.
Likely Use
Skin infection
This medicine is commonly prescribed for this.
Likely Use
Viral cold
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCefixime is absorbed from the gastrointestinal tract, with bioavailability estimated at 40-50% for the suspension and 50% for tablets. Ofloxacin is rapidly and almost completely absorbed, with bioavailability exceeding 95%. Food may slightly delay absorption but does not significantly affect the extent.
DistributionCefixime distributes widely into body tissues and fluids, including bile, sputum, and urine. Ofloxacin distributes extensively into most body tissues and fluids, including lung, skin, and prostate. Both drugs cross the placenta and are excreted in breast milk.
Protein BindingCefixime is about 65% bound to plasma proteins. Ofloxacin is approximately 20-30% bound to plasma proteins.
MetabolismCefixime is not significantly metabolized. Ofloxacin undergoes limited metabolism in the liver, with less than 10% metabolized to desmethyl and N-oxide metabolites.
Half-LifeThe elimination half-life of cefixime is approximately 3-4 hours in healthy adults. The elimination half-life of ofloxacin is approximately 4-5 hours, prolonged in renal impairment.
ExcretionCefixime is primarily excreted unchanged in the urine (about 50% of absorbed dose) and bile. Ofloxacin is mainly excreted unchanged in the urine (70-80%) and feces (about 20%).
BioavailabilityCefixime: 40-50% (suspension), 50% (tablet). Ofloxacin: >95%.
Onset of ActionCefixime: peak plasma concentration reached in 2-4 hours. Ofloxacin: peak plasma concentration reached in 1-2 hours. Clinical improvement may begin within 24-48 hours.
Peak Plasma TimeCefixime: 2-4 hours. Ofloxacin: 1-2 hours.
Duration of ActionBoth drugs have a duration of action that allows for once or twice daily dosing. Cefixime's effect lasts about 12-24 hours; ofloxacin's about 12-24 hours.

How It Works

This medicine combines two antibiotics with distinct mechanisms. Cefixime, a cephalosporin, inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis. Ofloxacin, a fluoroquinolone, inhibits DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. The combination provides a broader spectrum of activity and may be synergistic against certain bacteria.

Mechanism Steps

1
Cefixime binds to penicillin-binding proteins: Cefixime binds to specific penicillin-binding proteins on the bacterial cell membrane, inhibiting the cross-linking of peptidoglycan chains.
2
Inhibition of cell wall synthesis: This inhibition weakens the bacterial cell wall, leading to osmotic lysis and cell death.
3
Ofloxacin inhibits DNA gyrase: Ofloxacin binds to DNA gyrase and topoisomerase IV, enzymes that maintain DNA topology during replication.
4
Blockage of DNA replication: This binding prevents the relaxation of supercoiled DNA, halting replication and transcription, and ultimately causing bacterial cell death.

💡 How to Take alo cef 200mg/200mg tablet

Strength: Each tablet contains cefixime 200 mg and ofloxacin 200 mg.

1Take this medicine with a full glass of water.
2Take with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed.
5Do not take antacids, iron, or zinc within 2 hours of this medicine.
6Complete the full course even if you feel better.

Dosage Information

Adult DosageThe usual adult dose is one tablet (cefixime 200 mg + ofloxacin 200 mg) taken orally twice daily, or as prescribed by your doctor. The duration of treatment depends on the type and severity of infection. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced renal function and are at higher risk of tendon rupture and CNS effects. Dose adjustment may be necessary based on renal function. Use with caution.
Renal ImpairmentDose adjustment is required in patients with renal impairment. For creatinine clearance less than 50 mL/min, the dose may need to be reduced or the dosing interval extended. Consult your doctor for specific guidance.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution and monitor liver function.
Maximum Daily DoseThe maximum recommended daily dose is 400 mg of cefixime and 400 mg of ofloxacin, but this must be individualized by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and enhances absorption.
Dairy products
Separate by 2 hours
Calcium may bind to ofloxacin and reduce its absorption.
Caffeine
Limit intake
Ofloxacin may increase caffeine effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of alo cef 200mg/200mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food. If persistent, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If severe or bloody, seek medical attention.
Abdominal pain (Common (3-5%))
Usually resolves. If severe, contact your doctor.
Headache (Common (3-5%))
Rest and hydrate. If persistent, consult your doctor.
Dizziness (Common (2-4%))
Avoid driving if affected. Consult if it continues.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek emergency medical help immediately if you experience rash, swelling, difficulty breathing.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Report severe or bloody diarrhea to your doctor immediately.
Tendon rupture (Rare (<0.1%))
Stop the medicine and seek medical attention if you experience tendon pain or swelling.
Peripheral neuropathy (Rare (<0.1%))
Report numbness, tingling, or burning in extremities to your doctor.
Seizures (Rare (<0.1%))
Seek immediate medical attention if seizures occur.

⚠️ Rare Side Effects

Blood dyscrasias
Report unusual bruising or bleeding to your doctor.
Photosensitivity
Avoid sun exposure and use sunscreen.
Interstitial nephritis
Report decreased urine output or swelling to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Antacids Major
Theophylline Major
NSAIDs Major
Corticosteroids Moderate
Oral hypoglycemics Moderate
Probenecid Moderate
Caffeine Minor
Sucralfate Minor
Iron supplements Moderate

🚨 Major Interactions

  • Warfarin
  • Antacids, iron, zinc
  • Theophylline
  • NSAIDs

⚡ Moderate Interactions

  • Corticosteroids
  • Oral hypoglycemics
  • Probenecid

🍷 Alcohol Interaction

Alcohol may increase the risk of central nervous system side effects such as dizziness, drowsiness, and seizures. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cephalosporins, penicillins, or fluoroquinolones","History of tendon disorders with fluoroquinolones","Myasthenia gravis","Children under 18 years","Pregnancy and lactation","Severe renal impairment (dose adjustment required)"]

⚠️ Warnings & Precautions

["Serious hypersensitivity reactions, including anaphylaxis, have been reported.","Clostridioides difficile-associated diarrhea may occur; report severe diarrhea.","Tendon rupture, including Achilles tendon, can occur; stop drug if tendon pain occurs.","Peripheral neuropathy may occur; discontinue if symptoms develop.","Central nervous system effects including seizures, dizziness, and confusion have been reported.","May exacerbate muscle weakness in patients with myasthenia gravis.","Avoid excessive sun exposure due to photosensitivity risk.","Use with caution in patients with renal or hepatic impairment.","May cause false-positive urine glucose tests.","Do not use for viral infections."]

🤱 Lactation Safety

Both cefixime and ofloxacin are excreted in breast milk. Because of the potential risk of serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

💊 Overdose Management

There is no specific antidote for overdose. Treatment should be symptomatic and supportive. Maintain adequate hydration. Monitor renal function and electrolyte balance. Activated charcoal may be considered if ingestion is recent. Hemodialysis may be considered for ofloxacin overdose but is not effective for cefixime.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Take with food to reduce stomach upset. Avoid alcohol while taking this medicine as it may increase the risk of central nervous system side effects. Stay well hydrated. Do not take antacids, iron, or zinc supplements within 2 hours of this medicine as they can reduce absorption. Inform your doctor if you have kidney or liver problems, diabetes, or a history of tendon disorders. Avoid excessive sunlight and use sunscreen. Do not share this medicine with others. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of tendon rupture, CNS effects, and renal impairment. Dose adjustment may be necessary. Monitor renal function closely.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy or when planning pregnancy. Consult your doctor for safer alternatives.

🏥 Post-Surgery Considerations

Use with caution after surgery, especially if there is a risk of bleeding or renal impairment. Consult your surgeon before taking this medicine.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help flush out bacteria.
🥗
Maintain good hygiene to prevent reinfection.
😴
Get adequate rest to support your immune system.
💧
Eat a balanced diet rich in fruits and vegetables.
🧘
Avoid alcohol and smoking to improve recovery.
🌞
Complete the full course of antibiotics even if you feel better.

🏋️ Exercise Considerations

Avoid strenuous exercise or heavy lifting while taking this medicine, as it may increase the risk of tendon rupture. If you experience tendon pain, stop exercising and consult your doctor.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to maintain gut health.
Stay well hydrated.
Avoid excessive caffeine.
Limit dairy products close to the time of taking the medicine.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to take it with food and stay hydrated to minimize side effects.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to incomplete treatment and antibiotic resistance. If you experience serious side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to antibiotic resistance, superinfections, and rare but serious effects such as tendon rupture, peripheral neuropathy, and CNS effects. Regular monitoring of renal and liver function is recommended for prolonged therapy. Use only for the prescribed duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

Can help prevent antibiotic-associated diarrhea.

Evidence: Moderate
Increased fluid intake

Helps flush out bacteria in urinary tract infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Antibiotics may reduce the effectiveness of live bacterial vaccines such as typhoid vaccine. Consult your doctor about vaccination timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, adjust dosing times gradually, but maintain even intervals. Check local customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a urinary tract infection
She was prescribed this medicine for a complicated UTI. She took it with food twice daily and completed the 7-day course. Her symptoms improved within 3 days, and she experienced only mild nausea that resolved after the first few doses.
💡 Lesson: Taking the medicine with food and completing the full course led to successful treatment with minimal side effects.
👤 A 60-year-old man with chronic bronchitis
He was given this medicine for a bacterial exacerbation of chronic bronchitis. After 5 days, he noticed significant improvement in cough and breathing. He was advised to avoid alcohol and stay hydrated, which he followed diligently.
💡 Lesson: Adherence to lifestyle advice and medication schedule enhances recovery and prevents complications.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, take it with food to reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is it safe during pregnancy?

A: This medicine is generally avoided during pregnancy. Consult your doctor for alternative options.

Q: Can I drink alcohol while taking this medicine?

A: It is advisable to avoid alcohol as it may increase the risk of central nervous system side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for alo cef 200mg/200mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the flu.
    Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking this medicine once you feel better.
    Fact: You must complete the full course as prescribed to prevent the infection from returning and to reduce the risk of antibiotic resistance.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This medicine is a prescription-only antibiotic. Self-medication can lead to incorrect use, resistance, and serious side effects.

🔄 Alternative Options

Generic Alternatives

  • Cefixime + Ofloxacin (generic)

Brand Alternatives

  • Abixim O Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Cefixime + Ofloxacin","composition":"Cefixime 200 mg + Ofloxacin 200 mg","class":"Cephalosporin + Fluoroquinolone","route":"Oral","common_uses":"UTI, RTI, skin infections"},{"medicine":"Cefixime + Azithromycin","composition":"Cefixime 200 mg + Azithromycin 250 mg","class":"Cephalosporin + Macrolide","route":"Oral","common_uses":"RTI, typhoid"},{"medicine":"Amoxicillin + Clavulanic acid","composition":"Amoxicillin 500 mg + Clavulanic acid 125 mg","class":"Penicillin + Beta-lactamase inhibitor","route":"Oral","common_uses":"Sinusitis, otitis media, RTI"}]

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