alnacob forte tablet - Uses, Price, Side Effects & Substitutes
What is alnacob forte tablet used for?
Alnacob Forte Tablet (Alpha Lipoic Acid + Folic Acid) is used to treat NEURO CNS. It contains Alpha Lipoic Acid (100mg) + Folic Acid (1.5mg), which Alpha lipoic acid acts as a potent antioxidant, scavenging free radicals and reg. Always consult your doctor before use. Take as prescribed.
- Generic Name: Alpha Lipoic Acid + Folic Acid
- Manufacturer: Alna Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ alnacob forte tablet Uses & Benefits
Diabetic neuropathy, peripheral neuropathy, folic acid deficiency, prevention of neural tube defects in pregnancy, hyperhomocysteinemia.
Off-label uses: Alzheimer's disease, multiple sclerosis, chronic fatigue syndrome, heavy metal chelation (alpha lipoic acid).
๐ Drug Information
| Generic Name(s) | Alpha Lipoic Acid + Folic Acid |
| Brand Name | Alnacob Forte Tablet |
| Manufacturer | Alna Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Neuroprotective agent, Vitamin supplement |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Alpha lipoic acid acts as a potent antioxidant, scavenging free radicals and regenerating other antioxidants; it also improves insulin sensitivity and nerve function. Folic acid is essential for DNA synthesis, repair, and methylation; it reduces homocysteine levels.
Mechanism Steps
๐ก How to Take alnacob forte tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of alnacob forte tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Skin rash
- Headache
๐จ Serious Side Effects
- Hypoglycemia
- Lactic acidosis (alpha lipoic acid high doses)
- Allergic reactions
- Seizures
โ ๏ธ Rare Side Effects
- Insulin autoimmune syndrome
- Thrombocytopenia
- Leukopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk due to reduced warfarin metabolism |
| Methotrexate | Major | Decreased methotrexate efficacy; increased toxicity |
| Phenytoin | Major | Decreased phenytoin levels; increased seizure risk |
| Sulfasalazine | Major | Decreased folic acid absorption |
| Oral contraceptives | Moderate | Decreased folic acid levels |
| Antacids | Moderate | Decreased folic acid absorption |
| Cholestyramine | Minor | Decreased folic acid absorption |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Antiepileptics (phenytoin, carbamazepine)
- Sulfasalazine
โก Moderate Interactions
- Oral contraceptives
- Antacids
- H2 blockers
- Proton pump inhibitors
โน๏ธ Minor Interactions
- Cholestyramine
- Colestipol
- Triamterene
๐ฝ๏ธ Food Interactions
Absorption of alpha lipoic acid may be reduced by high-fat meals; folic acid absorption may be reduced by alcohol.
๐ท Alcohol Interaction
Alcohol may decrease folic acid absorption and increase its excretion; chronic alcohol use may lead to folate deficiency.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component; severe hepatic impairment; megaloblastic anemia due to vitamin B12 deficiency (folic acid may mask).
๐ Monitoring Parameters
Blood glucose, homocysteine levels, folate levels, neurological symptoms, liver function tests.
๐คฑ Lactation Safety
Both components are likely safe in lactation at recommended doses; alpha lipoic acid is excreted in
๐ Overdose Management
Supportive care; folic acid is water-soluble and excreted; alpha lipoic acid overdose may cause hypoglycemia, lactic acidosis; treat symptomatically.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose.