alfustat 10mg tablet

4.8 (12 reviews)

Alfuzosin (10mg)

🏭 Elder Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is alfustat 10mg tablet used for?

Alfoo (Alfuzosin) is used to treat UROLOGY. It contains Alfuzosin (10mg), which Selective antagonist of postsynaptic alpha-1 adrenergic receptors in the prostat. Always consult your doctor before use. Take as prescribed.

Generic Name: Alfuzosin
Manufacturer: Elder Pharmaceuticals Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 alfustat 10mg tablet Uses & Benefits

Treatment of signs and symptoms of benign prostatic hyperplasia (BPH).

Off-label uses: Treatment of ureteral stones (to facilitate passage), hypertension (not FDA approved).

📋 Drug Information

Generic Name(s)	Alfuzosin
Brand Name	Alfoo
Manufacturer	Elder Pharmaceuticals Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	UROLOGY
Action Class	Uroselective adrenergic receptor(α1a) antagonist
Route of Administration	Oral (immediate-release or extended-release tablets).
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; food delays absorption but does not affect extent.

DistributionVolume of distribution approximately 2.5 L/kg; extensively distributed to tissues.

Protein BindingApproximately 82-90% bound to plasma proteins.

MetabolismExtensively metabolized in the liver via CYP3A4; three main metabolites (inactive).

Half-Life5-7 hours (immediate-release); 9-10 hours (extended-release).

ExcretionPrimarily via feces (69%) and urine (24%) as metabolites; less than 1% excreted unchanged.

BioavailabilityApproximately 49% (immediate-release); 64% (extended-release) under fed conditions.

Onset of ActionWithin 1-2 hours.

Peak Plasma Time1-2 hours (immediate-release); 8 hours (extended-release).

Duration of Action24 hours (extended-release).

How It Works

Selective antagonist of postsynaptic alpha-1 adrenergic receptors in the prostate, bladder base, and prostatic urethra, leading to relaxation of smooth muscle and improved urine flow.

Mechanism Steps

1Alfuzosin selectively binds to alpha-1 adrenergic receptors on smooth muscle cells in the prostate, bladder base, and prostatic urethra.

2Receptor binding prevents activation by endogenous catecholamines (norepinephrine, epinephrine).

3Inhibition of receptor activation leads to relaxation of smooth muscle tone.

💡 How to Take alfustat 10mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of alfustat 10mg tablet

✅ Common Side Effects

Dizziness
Headache
Fatigue
Upper respiratory tract infection
Nasal congestion
Abdominal pain

🚨 Serious Side Effects

Orthostatic hypotension
Syncope
Priapism
Hepatotoxicity
Angioedema

⚠️ Rare Side Effects

Atrial fibrillation
Tachycardia
Jaundice
Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Ketoconazole	Major	Increased alfuzosin plasma concentration; risk of hypotension.
Sildenafil	Major	Increased risk of hypotension and syncope.
Warfarin	Minor	No significant interaction reported; monitor INR.

🚨 Major Interactions

CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
Other alpha-blockers (e.g., prazosin, terazosin)
Phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil)

⚡ Moderate Interactions

Antihypertensives (e.g., beta-blockers, calcium channel blockers)
CYP3A4 inducers (e.g., rifampin, carbamazepine)
Cimetidine

ℹ️ Minor Interactions

Warfarin
Digoxin
Antacids

🍽️ Food Interactions

Food delays absorption but does not affect overall bioavailability; take with food to reduce risk of orthostatic hypotension.

🍷 Alcohol Interaction

May increase risk of hypotension and dizziness; avoid excessive alcohol consumption.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to alfuzosin or any component; moderate to severe hepatic impairment; concomitant use with strong CYP3A4 inhibitors; history of orthostatic hypotension; micturition syncope.

📊 Monitoring Parameters

Blood pressure (especially at initiation), symptoms of orthostatic hypotension, urinary symptoms, liver function tests (if symptoms of hepatotoxicity).

🤱 Lactation Safety

Not indicated for use in women; excretion in breast milk unknown.

💊 Overdose Management

Induce emesis or gastric lavage; administer activated charcoal; monitor blood pressure and heart rate; treat hypotension with intravenous fluids and vasopressors if needed.

⏰ Missed Dose

Take the missed dose as soon as remembered; if close to next dose, skip the missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for alfustat 10mg tablet

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Alternative brands with exact same active ingredient (Alfuzosin (10mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.