Alflox 200mg Tablet: Complete Guide To Uses, Dosage, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden pain, swelling, or rupture of a tendon, especially in the ankle, knee, or shoulder.
- Numbness, tingling, burning, or weakness in the hands or feet.
- Seizures, severe confusion, hallucinations, or mood changes.
- Swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Severe, persistent diarrhea, abdominal cramping, or fever.
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain.
- Palpitations, fainting, or irregular heartbeat.
- Sudden, severe chest, back, or abdominal pain.
- Decreased urine output or inability to urinate.
- Severe headache with visual changes or sudden vision loss.
If experiencing severe symptoms, call emergency services immediately.
What is alflox 200mg tablet used for?
This medicine is a fluoroquinolone antibiotic containing norfloxacin 200 mg. It is used to treat urinary tract infections and certain other bacterial infections. It works by stopping bacteria from multiplying. Take it exactly as prescribed, usually twice daily, and avoid dairy or antacids within 2 hours of your dose.
- Generic Name: Norfloxacin
- Manufacturer: Alkem Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 alflox 200mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा नोरफ्लोक्सासिन 200 मिलीग्राम की एक एंटीबायोटिक गोली है, जिसका उपयोग मूत्र मार्ग के संक्रमण (यूटीआई), गुर्दे और मूत्राशय के संक्रमण, और कुछ अन्य बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह फ्लोरोक्विनोलोन वर्ग की दवा है और बैक्टीरिया को मारने का काम करती है। यह दवा केवल बैक्टीरिया से होने वाले संक्रमणों में प्रभावी है, वायरल संक्रमण जैसे सर्दी-जुकाम में नहीं। इसे डॉक्टर के निर्देशानुसार ही लें, और कोर्स पूरा करें।
साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं जैसे मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द, चक्कर आना और त्वचा पर दाने। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। लेकिन कुछ गंभीर दुष्प्रभाव भी हो सकते हैं, जिनमें टेंडन (नस) में दर्द या टूटना, हाथ-पैरों में झुनझुनी या सुन्नपन, दौरे पड़ना, भ्रम, गंभीर एलर्जी, और लंबे समय तक दस्त रहना शामिल है। अगर आपको कोई भी असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। इस दवा को दूध, दही, चीज़, या कैल्शियम, मैग्नीशियम, आयरन, जिंक वाले सप्लीमेंट्स के साथ न लें, क्योंकि इससे दवा का असर कम हो सकता है। इन्हें लेने से 2 घंटे पहले या बाद में दवा लें। पर्याप्त पानी पिएं। धूप में ज्यादा न जाएं और सनस्क्रीन का इस्तेमाल करें। शराब न पिएं। अगर आपको चक्कर आते हैं तो गाड़ी न चलाएं। कोर्स पूरा करें, बीच में दवा न छोड़ें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।
💊 alflox 200mg tablet Uses & Benefits
[{"condition":"Uncomplicated urinary tract infections (UTIs)","description":"This medicine is used to treat acute uncomplicated cystitis and pyelonephritis caused by susceptible gram-negative bacteria such as Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis.","evidence":"Well-established"},{"condition":"Complicated urinary tract infections","description":"It may be used for complicated UTIs, including those associated with structural abnormalities or catheterization, when the causative organism is susceptible.","evidence":"Established"},{"condition":"Gonorrhea","description":"This medicine has been used for the treatment of uncomplicated gonorrhea caused by Neisseria gonorrhoeae, though other agents are now preferred due to resistance.","evidence":"Limited due to resistance"},{"condition":"Bacterial gastroenteritis","description":"It may be prescribed for certain bacterial diarrheal illnesses, such as those caused by susceptible strains of Escherichia coli, but fluid and electrolyte management is primary.","evidence":"Limited"},{"condition":"Prostatitis","description":"This medicine can be used for chronic bacterial prostatitis caused by susceptible organisms, although other fluoroquinolones with better tissue penetration are often preferred.","evidence":"Limited"}]
Off-label uses: [{"condition":"Traveler's diarrhea","description":"Sometimes prescribed off-label for empirical treatment of traveler's diarrhea, but resistance is common and other antibiotics are generally preferred.","evidence":"Limited"},{"condition":"Spontaneous bacterial peritonitis prophylaxis","description":"Norfloxacin has been used off-label for prophylaxis of spontaneous bacterial peritonitis in patients with cirrhosis and ascites, but this is not a standard indication for this formulation.","evidence":"Limited"}]
Primary treatment for: Urinary tract infections
Also treats: Gonorrhea, Bacterial gastroenteritis, Prostatitis
📋 Drug Information
| Generic Name(s) | Norfloxacin |
| Brand Name | Alflox 400 Tablet |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Quinolones/ Fluroquinolones |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep the tablets in their original container, tightly closed. Do not store in the bathroom. Keep out of reach of children and pets. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture, but refer to the expiration date printed on the packaging. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine exerts its antibacterial effect by inhibiting two type II topoisomerase enzymes in susceptible bacteria: DNA gyrase (topoisomerase II) and topoisomerase IV. DNA gyrase is responsible for introducing negative supercoils into DNA, relieving torsional stress during replication, and topoisomerase IV is involved in decatenation of interlinked daughter DNA molecules after replication. By binding to these enzymes, this medicine stabilizes the enzyme-DNA cleavage complex, preventing the resealing of the DNA strand breaks. This leads to inhibition of DNA replication, transcription, repair, and recombination, ultimately causing bacterial cell death. The bactericidal action is concentration-dependent. Norfloxacin is active against a broad range of gram-negative bacteria and some gram-positive bacteria, but it has limited activity against anaerobes and is not effective against viruses.
Mechanism Steps
💡 How to Take alflox 200mg tablet
Strength: This medicine is available as a 200 mg immediate-release tablet for oral administration.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for uncomplicated urinary tract infections is 400 mg orally twice daily for 3 to 7 days, but the dose may vary depending on the indication, severity of infection, and renal function. For complicated UTIs, a longer duration may be required. For gonorrhea, a single 800 mg dose has been used historically, but resistance is common and other agents are preferred. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Norfloxacin is generally not recommended for children and adolescents due to the risk of cartilage and tendon damage, except in specific serious infections where the benefits outweigh the risks. |
| Elderly Dosage | Elderly patients (over 65 years) may have reduced renal function, which can increase the risk of norfloxacin accumulation and toxicity. Dosage should be adjusted based on creatinine clearance. Elderly patients are also at higher risk of tendon rupture, CNS effects, and cardiac arrhythmias. Use with caution and monitor renal function closely. |
| Renal Impairment | In patients with renal impairment, dosage adjustment is required. For creatinine clearance (CrCl) between 30 and 60 mL/min, a dose of 400 mg once daily may be sufficient. For CrCl less than 30 mL/min, a dose of 400 mg once daily or 200 mg twice daily may be used, but individualization is essential. In patients on hemodialysis, a dose of 400 mg may be given after dialysis. Always consult a clinician for precise dosing. |
| Hepatic Impairment | No specific dosage adjustment is provided for hepatic impairment in the available information. However, norfloxacin undergoes limited hepatic metabolism, so significant adjustment may not be necessary. Use with caution in patients with severe liver disease and monitor for adverse effects. |
| Maximum Daily Dose | The maximum recommended daily dose of norfloxacin is 800 mg per day, but this may vary based on the indication and clinical judgment. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of alflox 200mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Tizanidine | Major | |
| Theophylline | Major | |
| Warfarin | Major | |
| Antacids/sucralfate/minerals | Major | |
| Class IA/III antiarrhythmics | Major | |
| NSAIDs | Moderate | |
| Caffeine | Moderate | |
| Cyclosporine | Moderate | |
| Oral hypoglycemics/insulin | Moderate | |
| Probenecid | Moderate |
🚨 Major Interactions
- Tizanidine
- Theophylline
- Warfarin
- Antacids, sucralfate, and mineral supplements (calcium, magnesium, aluminum, iron, zinc)
- Class IA and III antiarrhythmics (e.g., quinidine, procainamide, amiodarone, sotalol)
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
⚡ Moderate Interactions
- Caffeine
- Cyclosporine
- Oral hypoglycemic agents (e.g., glibenclamide, insulin)
- Probenecid
- Nitrofurantoin
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Although norfloxacin does not directly interact with alcohol, both can cause central nervous system effects such as dizziness, drowsiness, and confusion. Alcohol may also worsen gastrointestinal side effects like nausea and abdominal discomfort. Additionally, alcohol can exacerbate the risk of seizures, which is a rare but serious side effect of fluoroquinolones. It is best to abstain from alcohol during the course of treatment and for a few days after completing it.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to norfloxacin, other fluoroquinolones, or any component of the formulation.","History of tendon disorders (tendinitis, tendon rupture) associated with fluoroquinolone use.","Myasthenia gravis (may worsen muscle weakness).","Pregnancy and breastfeeding (unless benefit outweighs risk).","Children and adolescents (except for specific serious infections where benefits outweigh risks).","Patients with a history of QT interval prolongation or uncorrected hypokalemia/hypomagnesemia.","Concomitant use with tizanidine."]
⚠️ Warnings & Precautions
["Fluoroquinolones, including norfloxacin, have been associated with disabling and potentially irreversible serious adverse reactions, including tendinitis, tendon rupture, peripheral neuropathy, and CNS effects. Reserve use for patients with no alternative treatment options for certain infections.","Tendon rupture can occur during or after therapy, most commonly in the Achilles tendon, and may be bilateral. Risk is increased in patients over 60 years, those taking corticosteroids, and organ transplant recipients.","Peripheral neuropathy may be irreversible. Discontinue if symptoms occur.","CNS effects including seizures, confusion, and hallucinations have been reported. Use with caution in patients with known or suspected CNS disorders.","Clostridioides difficile-associated diarrhea may occur. Evaluate if diarrhea develops.","Avoid excessive sunlight and use sunscreen due to photosensitivity risk.","Monitor blood glucose in diabetic patients; severe hypoglycemia has been reported.","May exacerbate myasthenia gravis. Avoid use in these patients.","Not recommended for use in children except for specific serious infections.","Do not use for viral infections; it is ineffective and promotes resistance."]
🤱 Lactation Safety
Norfloxacin is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, including effects on cartilage and tendon development, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Breastfeeding is generally not recommended while taking this medicine.
💊 Overdose Management
There is no specific antidote for norfloxacin overdose. Management should be symptomatic and supportive. In case of acute overdose, empty the stomach by inducing emesis or gastric lavage if appropriate. Maintain adequate hydration to prevent crystalluria. Monitor vital signs, ECG, and renal function. Hemodialysis or peritoneal dialysis does not effectively remove norfloxacin from the body. Contact a poison control center or emergency department immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have kidney disease, liver disease, diabetes, epilepsy or other seizure disorders, myasthenia gravis, heart rhythm problems, or a history of tendon problems. Avoid taking this medicine with dairy products, antacids, or mineral supplements containing calcium, magnesium, aluminum, iron, or zinc within 2 hours before or after your dose, as they can reduce absorption. Maintain adequate hydration during treatment. Avoid excessive sunlight and use sunscreen, as this medicine can make your skin more sensitive to sunlight. Do not drive or operate heavy machinery if you experience dizziness or confusion. Avoid alcohol while taking this medicine as it may increase central nervous system side effects. Complete the full course as prescribed even if you feel better, to prevent resistance. Do not share this medicine with others. If you experience pain, swelling, or rupture of a tendon, stop taking this medicine and seek immediate medical attention. If you develop numbness or tingling in your hands or feet, contact your doctor. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. This medicine is not recommended during pregnancy or breastfeeding unless clearly needed. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (over 65 years) are at increased risk of tendon rupture, central nervous system effects, and cardiac arrhythmias when taking this medicine. Renal function declines with age, so dosage adjustment may be necessary based on creatinine clearance. Monitor for signs of confusion, dizziness, and tendon pain. Ensure adequate hydration. Use with caution and consider alternative antibiotics if available.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. Fluoroquinolones are generally not recommended during pregnancy due to potential risks to fetal cartilage development. If you become pregnant while taking this medicine, contact your doctor immediately. Alternative antibiotics may be safer for treating infections during pregnancy.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with other medications used during surgery and can affect blood sugar levels. Your doctor may adjust the dose or timing of this medicine around your surgery. Do not stop taking it without consulting your doctor.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine may interact with certain antibiotics or anesthetics used in dentistry. It can also cause dry mouth or taste disturbances. Maintain good oral hygiene and stay hydrated. If you need dental work, your dentist may coordinate with your doctor to ensure safety.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you should avoid strenuous exercise or high-impact activities, as fluoroquinolones increase the risk of tendon rupture. If you experience any tendon pain, swelling, or discomfort, stop exercising and consult your doctor immediately. Light activities like walking are generally safe, but listen to your body and do not push through pain.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or confusion, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how this medicine affects you. If your work involves physical labor, be cautious about tendon pain and avoid strenuous activities. Take sick leave if needed to rest and recover. Inform your employer if you need accommodations.
🛑 When to Stop This Medicine
You should stop taking this medicine only after completing the full prescribed course, unless your doctor advises otherwise. If you experience serious side effects such as tendon pain, numbness, seizures, or severe allergic reactions, stop taking it immediately and seek medical attention. Do not stop early just because you feel better, as this can lead to recurrence of infection and antibiotic resistance. Always consult your doctor before stopping this medicine.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to bacterial resistance, making future infections harder to treat. It may also increase the risk of tendon damage, peripheral neuropathy, and central nervous system effects. Prolonged use can disrupt the normal gut flora, leading to diarrhea or fungal infections. Regular monitoring of kidney and liver function may be required if used for extended periods. This medicine should only be used for the shortest duration necessary to treat the infection.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Drinking plenty of water helps flush out bacteria from the urinary tract and can complement antibiotic therapy.
Evidence: Well-establishedCranberry juice or supplements may help prevent UTIs by preventing bacteria from adhering to the bladder wall, but evidence for treatment is limited.
Evidence: LimitedProbiotics may help restore gut flora disrupted by antibiotics and reduce the risk of antibiotic-associated diarrhea.
Evidence: ModerateThis is a urinary analgesic that can relieve burning and urgency symptoms but does not treat the infection. It may be used as an adjunct.
Evidence: Well-established for symptom relief💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, if you are due for any vaccinations, inform your doctor that you are taking this antibiotic. Live vaccines should generally be avoided during antibiotic therapy, but inactivated vaccines are safe. Complete your vaccination schedule as recommended by your healthcare provider.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specified.
✅ DO
Keep in the original container, tightly closed.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of reach of children and pets.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label clearly visible. Bring a copy of your prescription or a letter from your doctor, especially for international travel, as some countries have strict rules about antibiotics. Store the medicine in a cool, dry place, away from direct sunlight and moisture. If you are crossing time zones, adjust your dosing schedule to maintain even intervals, but consult your doctor for specific advice. Always pack this medicine in your carry-on luggage to avoid loss or temperature extremes in checked baggage. Check customs regulations of your destination regarding antibiotics.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours, but it is important to complete the full course as prescribed. If symptoms do not improve within 48 to 72 hours, contact your doctor.
A: It is best to take this medicine on an empty stomach, at least 1 hour before or 2 hours after a meal. If it upsets your stomach, you may take it with a light meal, but avoid dairy products.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: This medicine is generally not recommended during pregnancy unless clearly needed. Consult your doctor if you are pregnant or planning pregnancy.
A: It is best to avoid alcohol while taking this medicine, as it may increase dizziness, drowsiness, and the risk of seizures.
A: Seek immediate medical attention if you experience tendon pain or swelling, numbness or tingling in hands or feet, seizures, severe allergic reactions, or severe diarrhea.
A: No, you must complete the full prescribed course even if you feel better, to prevent the infection from returning and to avoid antibiotic resistance.
A: Yes, it can interact with antacids, dairy products, warfarin, theophylline, tizanidine, and some antiarrhythmics. Always inform your doctor about all medicines you are taking.
A: Store at room temperature between 15°C and 30°C, away from light and moisture. Keep in the original container and out of reach of children.
A: This medicine is generally not recommended for children and adolescents due to the risk of joint and tendon problems, except in specific serious infections where the benefits outweigh the risks. Consult a pediatrician.
🤔 Common Patient Concerns
🔄 Substitutes for alflox 200mg tablet
View AllAlternative brands with exact same active ingredient:
-
norflin 200mg tabletAan Pharma Pvt Ltd ₹19.00 14.3% CHEAPER
-
norbid 200mg tabletAlembic Pharmaceuticals Ltd ₹19.64 11.4% CHEAPER
-
noraxin 200mg tabletAcron Pharmaceuticals ₹21.56 2.8% CHEAPER
-
klib 200mg tabletEmcee Pharmaceuticals Pvt Ltd ₹23.32 5.2% COSTLIER
-
norilet 200mg tabletDr Reddy's Laboratories Ltd ₹23.40 5.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any infection.
Fact: This medicine is only effective against certain bacterial infections, not viruses or all bacteria. It should be used only for susceptible organisms. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full prescribed course to prevent bacterial resistance and recurrence of infection. - Myth: This medicine is safe to take with dairy products.
Fact: Dairy products can reduce the absorption of this medicine. Avoid taking them within 2 hours of your dose. - Myth: This medicine is safe during pregnancy.
Fact: This medicine is generally not recommended during pregnancy unless clearly needed, as it may affect fetal development. - Myth: This medicine can be shared with family members.
Fact: Never share antibiotics. They are prescribed for a specific infection and sharing can lead to inappropriate use and resistance.
🔄 Alternative Options
Generic Alternatives
- Norfloxacin 200 mg tablet
- Norfloxacin 400 mg tablet
Brand Alternatives
- Alflox 200mg tablet
- Norflox 200mg tablet
- Norbactin 200mg tablet