Alfanage 10mg/0.5mg Tablet - Uses, Price, Side Effects
What is alfanage 10mg/0.5mg tablet used for?
Alfanage 10mg/0.5mg tablet is a combination of Alfuzosin (10mg) and Dutasteride (0.5mg) used to treat benign prostatic hyperplasia (BPH). Alfuzosin relaxes muscles in the prostate and bladder neck, while Dutasteride reduces prostate size by inhibiting hormone production, improving urine flow and reducing symptoms.
- Generic Name: Alfuzosin + Dutasteride
- Manufacturer: Allenge India
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ alfanage 10mg/0.5mg tablet Uses & Benefits
Benign prostatic hyperplasia (BPH)
Off-label uses: Male pattern baldness (dutasteride alone)
๐ Drug Information
| Generic Name(s) | Alfuzosin + Dutasteride |
| Brand Name | Alfugress-D Tablet SR |
| Manufacturer | Allenge India |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | UROLOGY |
| Action Class | Alpha-1 adrenergic blocker + 5-alpha-reductase inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC, protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Alfuzosin: Blocks alpha-1 adrenoceptors in prostate/bladder neck; Dutasteride: Inhibits 5-alpha-reductase, reducing DHT
Mechanism Steps
๐ก How to Take alfanage 10mg/0.5mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of alfanage 10mg/0.5mg tablet
โ Common Side Effects
- Dizziness
- Headache
- Fatigue
- Nasopharyngitis
- Decreased libido
- Erectile dysfunction
- Ejaculation disorders
๐จ Serious Side Effects
- Orthostatic hypotension
- Syncope
- Priapism
- Breast cancer (rare)
โ ๏ธ Rare Side Effects
- Angioedema
- Hepatotoxicity
- Depression
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Ketoconazole | Moderate | Increased dutasteride levels |
| Prazosin | Moderate | Enhanced hypotensive effect |
๐จ Major Interactions
- CYP3A4 inhibitors (ketoconazole, ritonavir)
- Other alpha-blockers
- Antihypertensives
โก Moderate Interactions
- Cimetidine
- Warfarin
- CYP3A4 inducers
โน๏ธ Minor Interactions
- Digoxin
- Theophylline
๐ฝ๏ธ Food Interactions
Alfuzosin: Food increases absorption; Dutasteride: No significant effect
๐ท Alcohol Interaction
May increase hypotension risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe hepatic impairment, orthostatic hypotension, women/children
๐ Monitoring Parameters
Blood pressure, prostate-specific antigen (PSA), liver function
๐คฑ Lactation Safety
Not recommended; Dutasteride excreted in breast milk
๐ Overdose Management
Symptomatic and supportive; hypotension treatment
โฐ Missed Dose
Take as soon as remembered; skip if near next dose