Alersafe M Oral Suspension - Uses, Price, Side Effects
What is alersafe m oral suspension used for?
Alersafe M Oral Suspension is a combination medicine containing Levocetirizine (an antihistamine) and Montelukast (a leukotriene receptor antagonist). It is used to relieve symptoms of allergic rhinitis such as sneezing, runny nose, and itching, and to prevent asthma attacks. Levocetirizine blocks histamine, while Montelukast reduces inflammation in the airways.
- Generic Name: Levocetirizine + Montelukast
- Manufacturer: Medrix Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ alersafe m oral suspension Uses & Benefits
Seasonal and perennial allergic rhinitis; asthma prophylaxis
Off-label uses: Urticaria, Eosinophilic esophagitis
๐ Drug Information
| Generic Name(s) | Levocetirizine + Montelukast |
| Brand Name | Allercet-M Tablet |
| Manufacturer | Medrix Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Leukotriene Receptor Antagonist |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Levocetirizine selectively inhibits peripheral H1 receptors; Montelukast antagonizes leukotriene D4 at CysLT1 receptors
Mechanism Steps
๐ก How to Take alersafe m oral suspension
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of alersafe m oral suspension
โ Common Side Effects
- Headache
- Drowsiness
- Dry mouth
- Cough
- Pharyngitis
๐จ Serious Side Effects
- Angioedema
- Anaphylaxis
- Neuropsychiatric events (agitation, depression)
โ ๏ธ Rare Side Effects
- Hepatitis
- Thrombocytopenia
- Seizures
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | Increased risk of bleeding |
| Theophylline | Moderate | Increased theophylline levels |
| Ketoconazole | Minor | Reduced montelukast metabolism |
๐จ Major Interactions
- CYP3A4 inducers (e.g., Rifampin)
- CYP2C9 inducers (e.g., Phenobarbital)
โก Moderate Interactions
- Gemfibrozil
- Itraconazole
- Warfarin
โน๏ธ Minor Interactions
- Theophylline
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Montelukast absorption decreased by high-fat meal; take on empty stomach
๐ท Alcohol Interaction
Levocetirizine may potentiate CNS depression
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component; severe renal impairment (CrCl <10 mL/min) for levocetirizine
๐ Monitoring Parameters
Renal function, hepatic function, signs of neuropsychiatric events
๐คฑ Lactation Safety
Levocetirizine excreted in breast milk; caution advised
๐ Overdose Management
Symptomatic and supportive; no specific antidote
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double