alentos 0.5mg tablet

4.5 (14 reviews)

Entecavir (0.5mg)

🏭 Wockhardt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is alentos 0.5mg tablet used for?

Anticanol 0.5 Tablet (Entecavir) is used to treat ANTI INFECTIVES. It contains Entecavir (0.5mg), which Entecavir is a guanosine nucleoside analogue that inhibits hepatitis B virus (HB. Always consult your doctor before use. Take as prescribed.

Generic Name: Entecavir
Manufacturer: Wockhardt Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 alentos 0.5mg tablet Uses & Benefits

Chronic hepatitis B virus infection in adults with compensated or decompensated liver disease.

Off-label uses: Prophylaxis of hepatitis B reactivation in immunosuppressed patients.

📋 Drug Information

Generic Name(s)	Entecavir
Brand Name	Anticanol 0.5 Tablet
Manufacturer	Wockhardt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI INFECTIVES
Action Class	Nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs)
Route of Administration	Oral.
Storage	Store at 20-25°C (68-77°F); protect from moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration with peak plasma concentrations within 0.5-1.5 hours.

DistributionWidely distributed into tissues; volume of distribution approximately 0.7 L/kg.

Protein BindingApproximately 13% bound to human serum proteins.

MetabolismNot significantly metabolized; minor glucuronidation and sulfation.

Half-LifeApproximately 128-149 hours (accumulation half-life).

ExcretionPrimarily excreted unchanged in urine (62-73%) via glomerular filtration and tubular secretion.

BioavailabilityApproximately 100% after oral administration.

Onset of ActionRapid; viral suppression begins within days.

Peak Plasma Time0.5-1.5 hours.

Duration of ActionLong duration due to long half-life; once-daily dosing.

How It Works

Entecavir is a guanosine nucleoside analogue that inhibits hepatitis B virus (HBV) polymerase. It undergoes intracellular phosphorylation to the active triphosphate form, which competes with natural deoxyguanosine triphosphate and inhibits HBV DNA polymerase (reverse transcriptase) activity, leading to inhibition of viral replication.

Mechanism Steps

1Entecavir enters hepatocytes via nucleoside transporters.

2Intracellular phosphorylation by cellular kinases to entecavir triphosphate.

3Competitive inhibition of HBV DNA polymerase (reverse transcriptase) by binding to the enzyme.

💡 How to Take alentos 0.5mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of alentos 0.5mg tablet

✅ Common Side Effects

Headache
Fatigue
Dizziness
Nausea
Diarrhea
Dyspepsia
Insomnia

🚨 Serious Side Effects

Lactic acidosis
Severe hepatomegaly with steatosis
Acute exacerbation of hepatitis B upon discontinuation
Pancreatitis

⚠️ Rare Side Effects

Alopecia
Rash
Myalgia
Arthralgia
Elevated amylase/lipase

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Lamivudine	Major	Potential for cross-resistance; combination not recommended.
Adefovir	Major	Increased risk of nephrotoxicity; monitor renal function.
Tenofovir	Major	Increased risk of nephrotoxicity; monitor renal function.
Interferon alfa	Major	Possible additive myelosuppression.

🚨 Major Interactions

Lamivudine
Adefovir
Tenofovir
Interferon alfa

⚡ Moderate Interactions

Nucleoside analogues
Immunosuppressants

ℹ️ Minor Interactions

Acetaminophen
Ibuprofen

🍽️ Food Interactions

Food delays absorption and reduces peak concentration; take on an empty stomach (at least 2 hours before or after a meal).

🍷 Alcohol Interaction

Alcohol may increase hepatotoxicity risk; avoid or limit alcohol consumption.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to entecavir or any component of the formulation.

📊 Monitoring Parameters

HBV DNA levels, ALT, AST, bilirubin, renal function, HIV status (test before initiation).

🤱 Lactation Safety

Not recommended; excreted in human milk; consider risk to infant.

💊 Overdose Management

Limited experience; supportive care; hemodialysis may remove entecavir (approximately 30% in 4 hours).

⏰ Missed Dose

Take as soon as remembered unless it is almost time for next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

🔗 View Profile

🔄 Substitutes for alentos 0.5mg tablet

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Alternative brands with exact same active ingredient (Entecavir (0.5mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

alentos 0.5mg tablet

What is alentos 0.5mg tablet used for?

💊 alentos 0.5mg tablet Uses & Benefits

📋 Drug Information

🔬 Pharmacology (PK/PD)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take alentos 0.5mg tablet

⚠️ Side Effects of alentos 0.5mg tablet

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

ℹ️ Minor Interactions

🍽️ Food Interactions

🍷 Alcohol Interaction

🛡️ Safety & Warnings

🚫 Contraindications

📊 Monitoring Parameters

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

🔄 Substitutes for alentos 0.5mg tablet

⭐ User Reviews

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