alecta plus 325mg/37.5mg tablet - Paracetamol/Acetaminophen (325mg) + Tramadol (37.5mg) medicine

alecta plus 325mg/37.5mg tablet

4.8 (13 reviews)
๐Ÿญ SandMartin Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is alecta plus 325mg/37.5mg tablet used for?

Acuvin Tablet (Paracetamol/Acetaminophen + Tramadol) is used to treat PAIN ANALGESICS. It contains Paracetamol/Acetaminophen (325mg) + Tramadol (37.5mg), which Paracetamol: Inhibits cyclooxygenase (COX) in the CNS, reducing prostaglandin sy. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Paracetamol/Acetaminophen + Tramadol
  • Manufacturer: SandMartin Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š alecta plus 325mg/37.5mg tablet Uses & Benefits

Moderate to severe pain, acute pain, postoperative pain

Off-label uses: Chronic pain, neuropathic pain (tramadol component)

๐Ÿ“‹ Drug Information

Generic Name(s)Paracetamol/Acetaminophen + Tramadol
Brand NameAcuvin Tablet
ManufacturerSandMartin Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassPAIN ANALGESICS
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture and light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed from the gastrointestinal tract.
DistributionDistributed throughout body fluids; crosses placenta and enters breast milk.
Protein BindingParacetamol: 10-25%; Tramadol: 20%
MetabolismParacetamol: Hepatic via conjugation (glucuronidation, sulfation) and CYP2E1; Tramadol: Hepatic via CYP2D6 and CYP3A4 to active metabolite O-desmethyltramadol (M1).
Half-LifeParacetamol: 1.5-2.5 hours; Tramadol: 5-6 hours (M1: 7-9 hours)
ExcretionParacetamol: Renal (mostly as conjugates); Tramadol: Renal (90%) and feces (10%)
BioavailabilityParacetamol: 85-90%; Tramadol: 75%
Onset of ActionParacetamol: 30-60 minutes; Tramadol: 30-60 minutes
Peak Plasma TimeParacetamol: 0.5-2 hours; Tramadol: 1-2 hours
Duration of ActionParacetamol: 4-6 hours; Tramadol: 4-6 hours

How It Works

Paracetamol: Inhibits cyclooxygenase (COX) in the CNS, reducing prostaglandin synthesis; Tramadol: Binds to mu-opioid receptors and inhibits serotonin/norepinephrine reuptake.

Mechanism Steps

1Paracetamol inhibits COX enzymes in the CNS, reducing prostaglandin synthesis and pain perception.
2Tramadol binds to mu-opioid receptors, activating G-protein coupled signaling and reducing pain transmission.
3Tramadol inhibits serotonin and norepinephrine reuptake, enhancing descending inhibitory pain pathways.

๐Ÿ’ก How to Take alecta plus 325mg/37.5mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of alecta plus 325mg/37.5mg tablet

โœ… Common Side Effects

  • Nausea
  • dizziness
  • drowsiness
  • constipation
  • headache
  • sweating

๐Ÿšจ Serious Side Effects

  • Seizures
  • serotonin syndrome
  • respiratory depression
  • hepatotoxicity
  • hypotension
  • allergic reactions

โš ๏ธ Rare Side Effects

  • QT prolongation
  • adrenal insufficiency
  • pancreatitis
  • toxic epidermal necrolysis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Risk of serotonin syndrome, hypertensive crisis
SSRIs Major Increased risk of serotonin syndrome
Warfarin Moderate Increased INR and bleeding risk
Alcohol Major Hepatotoxicity and CNS depression

๐Ÿšจ Major Interactions

  • MAOIs
  • SSRIs
  • SNRIs
  • TCAs
  • Linezolid
  • Methylene blue
  • CNS depressants (alcohol, benzodiazepines)
  • Carbamazepine
  • Rifampin
  • Phenytoin

โšก Moderate Interactions

  • Anticoagulants (warfarin)
  • Anticholinergics
  • Digoxin
  • Metoclopramide
  • Domperidone

โ„น๏ธ Minor Interactions

  • Cholestyramine
  • Oral contraceptives

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but not extent.

๐Ÿท Alcohol Interaction

Increased risk of hepatotoxicity with paracetamol; additive CNS depression with tramadol.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, severe hepatic impairment, acute asthma, respiratory depression, MAOI use within 14 days, seizure disorders, acute intoxication with alcohol or CNS depressants

๐Ÿ“Š Monitoring Parameters

Pain relief, respiratory rate, liver function tests, renal function, signs of serotonin syndrome

๐Ÿคฑ Lactation Safety

Paracetamol: Safe; Tramadol: Use with caution, monitor infant for sedation

๐Ÿ’Š Overdose Management

Paracetamol: N-acetylcysteine; Tramadol: Naloxone (may increase seizure risk), supportive care

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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