aldol p 325mg/50mg tablet - Uses, Price, Side Effects & Substitutes
What is aldol p 325mg/50mg tablet used for?
Acuvin Tablet (Paracetamol/Acetaminophen + Tramadol) is used to treat PAIN ANALGESICS. It contains Paracetamol/Acetaminophen (325mg) + Tramadol (50mg), which Paracetamol: Inhibits cyclooxygenase (COX) in the CNS, reducing prostaglandin sy. Always consult your doctor before use. Take as prescribed.
- Generic Name: Paracetamol/Acetaminophen + Tramadol
- Manufacturer: Altar Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ aldol p 325mg/50mg tablet Uses & Benefits
Moderate to severe pain, acute pain, postoperative pain
Off-label uses: Chronic pain, neuropathic pain (tramadol component)
๐ Drug Information
| Generic Name(s) | Paracetamol/Acetaminophen + Tramadol |
| Brand Name | Acuvin Tablet |
| Manufacturer | Altar Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | PAIN ANALGESICS |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Paracetamol: Inhibits cyclooxygenase (COX) in the CNS, reducing prostaglandin synthesis; Tramadol: Binds to mu-opioid receptors and inhibits serotonin/norepinephrine reuptake.
Mechanism Steps
๐ก How to Take aldol p 325mg/50mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of aldol p 325mg/50mg tablet
โ Common Side Effects
- Nausea
- dizziness
- drowsiness
- constipation
- headache
- sweating
๐จ Serious Side Effects
- Seizures
- serotonin syndrome
- respiratory depression
- hepatotoxicity
- hypotension
- allergic reactions
โ ๏ธ Rare Side Effects
- QT prolongation
- adrenal insufficiency
- pancreatitis
- toxic epidermal necrolysis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Risk of serotonin syndrome, hypertensive crisis |
| SSRIs | Major | Increased risk of serotonin syndrome |
| Warfarin | Moderate | Increased INR and bleeding risk |
| Alcohol | Major | Hepatotoxicity and CNS depression |
๐จ Major Interactions
- MAOIs
- SSRIs
- SNRIs
- TCAs
- Linezolid
- Methylene blue
- CNS depressants (alcohol, benzodiazepines)
- Carbamazepine
- Rifampin
- Phenytoin
โก Moderate Interactions
- Anticoagulants (warfarin)
- Anticholinergics
- Digoxin
- Metoclopramide
- Domperidone
โน๏ธ Minor Interactions
- Cholestyramine
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Food may delay absorption but not extent.
๐ท Alcohol Interaction
Increased risk of hepatotoxicity with paracetamol; additive CNS depression with tramadol.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe hepatic impairment, acute asthma, respiratory depression, MAOI use within 14 days, seizure disorders, acute intoxication with alcohol or CNS depressants
๐ Monitoring Parameters
Pain relief, respiratory rate, liver function tests, renal function, signs of serotonin syndrome
๐คฑ Lactation Safety
Paracetamol: Safe; Tramadol: Use with caution, monitor infant for sedation
๐ Overdose Management
Paracetamol: N-acetylcysteine; Tramadol: Naloxone (may increase seizure risk), supportive care
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose