Agyvit-G Tablet - Uses, Price, Side Effects
What is agyvit-g tablet used for?
Agyvit-G Tablet is a combination medicine containing Gabapentin (300mg) and Methylcobalamin (500mcg). It is used to treat neuropathic pain and nerve damage. Gabapentin works by calming overactive nerves, while Methylcobalamin helps repair nerve tissue. Take it as prescribed by your doctor.
- Generic Name: Gabapentin + Methylcobalamin
- Manufacturer: Healthserch Pharma LLP
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ agyvit-g tablet Uses & Benefits
Neuropathic pain, epilepsy (adjunctive), peripheral neuropathy, restless legs syndrome
Off-label uses: Anxiety, bipolar disorder, hot flashes, fibromyalgia
๐ Drug Information
| Generic Name(s) | Gabapentin + Methylcobalamin |
| Brand Name | Alfagaba 100 Tablet |
| Manufacturer | Healthserch Pharma LLP |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Anticonvulsant, Neurotropic agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Gabapentin binds to ฮฑ2ฮด subunit of voltage-gated calcium channels, reducing calcium influx and neurotransmitter release. Methylcobalamin acts as a cofactor for methionine synthase and methylmalonyl-CoA mutase, promoting myelin synthesis and nerve regeneration.
Mechanism Steps
๐ก How to Take agyvit-g tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of agyvit-g tablet
โ Common Side Effects
- Dizziness
- Somnolence
- Peripheral edema
- Ataxia
- Fatigue
- Nausea
๐จ Serious Side Effects
- Angioedema
- Suicidal ideation
- Respiratory depression
- Stevens-Johnson syndrome
- Drug reaction with eosinophilia and systemic symptoms (DRESS)
โ ๏ธ Rare Side Effects
- Pancreatitis
- Rhabdomyolysis
- Hepatotoxicity
- Myoclonus
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | Increased dizziness and drowsiness |
| Opioid analgesics | Major | Increased CNS depression and respiratory depression |
| Antacids | Moderate | Reduced gabapentin absorption |
๐จ Major Interactions
- Opioids
- Antacids
- Cimetidine
- Hydrocodone
- Morphine
โก Moderate Interactions
- NSAIDs
- Antidiabetic agents
- Losartan
- Ethanol
โน๏ธ Minor Interactions
- Oral contraceptives
- Antacids (aluminum/magnesium)
๐ฝ๏ธ Food Interactions
High-fat meals may decrease gabapentin absorption, Avoid excessive alcohol
๐ท Alcohol Interaction
Increased CNS depression; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to gabapentin or methylcobalamin, severe renal impairment (CrCl <30 mL/min for gabapentin)
๐ Monitoring Parameters
Renal function, CNS effects (dizziness, sedation), therapeutic response (pain, seizure control)
๐คฑ Lactation Safety
Gabapentin excreted in breast milk; caution advised. Methylcobalamin is safe.
๐ Overdose Management
Supportive care; hemodialysis may remove gabapentin. Monitor CNS depression.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.