agipine 7.5mg tablet

4.6 (14 reviews)

Mirtazapine (7.5mg)

🏭 AGM Biotec 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is agipine 7.5mg tablet used for?

Agipine (Mirtazapine) is used to treat NEURO CNS. It contains Mirtazapine (7.5mg), which Antagonist at presynaptic alpha-2 adrenergic receptors, leading to increased nor. Always consult your doctor before use. Take as prescribed.

Generic Name: Mirtazapine
Manufacturer: AGM Biotec
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 agipine 7.5mg tablet Uses & Benefits

Major depressive disorder; off-label for anxiety, insomnia, PTSD, and appetite stimulation.

Off-label uses: Anxiety disorders, Insomnia, Post-traumatic stress disorder, Appetite stimulation in cachexia

📋 Drug Information

Generic Name(s)	Mirtazapine
Brand Name	Agipine
Manufacturer	AGM Biotec
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	NEURO CNS
Action Class	Noradrenergic and specific serotonergic antidepressants (NASSAs)
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed after oral administration; food does not affect absorption.

DistributionWidely distributed throughout the body; volume of distribution approximately 1.0 L/kg.

Protein BindingApproximately 85% bound to plasma proteins.

MetabolismExtensively metabolized in the liver via CYP2D6, CYP3A4, and CYP1A2; major metabolites include demethylmirtazapine and 8-hydroxymirtazapine.

Half-LifeApproximately 20-40 hours (mean 30 hours).

ExcretionPrimarily renal (75% as metabolites, 15% as unchanged drug); fecal excretion accounts for about 15%.

BioavailabilityApproximately 50% due to first-pass metabolism.

Onset of ActionTherapeutic effects may be seen within 1-2 weeks; full effect may take 4-6 weeks.

Peak Plasma TimeApproximately 2 hours post-dose.

Duration of Action24 hours (once-daily dosing).

How It Works

Antagonist at presynaptic alpha-2 adrenergic receptors, leading to increased norepinephrine and serotonin release; also antagonizes 5-HT2 and 5-HT3 receptors.

Mechanism Steps

1Mirtazapine blocks presynaptic alpha-2 adrenergic receptors on noradrenergic and serotonergic neurons.

2Blockade of alpha-2 autoreceptors increases norepinephrine release from noradrenergic neurons.

3Blockade of alpha-2 heteroreceptors on serotonergic neurons increases serotonin release.

💡 How to Take agipine 7.5mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of agipine 7.5mg tablet

✅ Common Side Effects

Somnolence
Increased appetite
Weight gain
Dry mouth
Constipation
Dizziness

🚨 Serious Side Effects

Agranulocytosis
Serotonin syndrome
Suicidal thoughts
Seizures

⚠️ Rare Side Effects

Jaundice
Pancreatitis
Stevens-Johnson syndrome
Hypomania

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
MAOIs	Major	Increased risk of serotonin syndrome
Linezolid	Major	Increased risk of serotonin syndrome
Methylene blue	Major	Increased risk of serotonin syndrome
CYP2D6 inhibitors	Moderate	Increased mirtazapine levels
CYP3A4 inhibitors	Moderate	Increased mirtazapine levels
CYP1A2 inhibitors	Moderate	Increased mirtazapine levels
CNS depressants	Moderate	Enhanced sedation
Serotonergic drugs	Moderate	Increased risk of serotonin syndrome
Warfarin	Minor	Possible increased INR
Phenytoin	Minor	Decreased mirtazapine levels
Carbamazepine	Minor	Decreased mirtazapine levels

🚨 Major Interactions

MAOIs
Linezolid
Methylene blue

⚡ Moderate Interactions

CYP2D6 inhibitors (e.g., paroxetine, fluoxetine)
CYP3A4 inhibitors (e.g., ketoconazole)
CYP1A2 inhibitors (e.g., ciprofloxacin)
CNS depressants (e.g., benzodiazepines, alcohol)
Serotonergic drugs (e.g., SSRIs, SNRIs, triptans)

ℹ️ Minor Interactions

Warfarin
Phenytoin
Carbamazepine

🍽️ Food Interactions

No significant food interactions; avoid grapefruit juice (may increase levels).

🍷 Alcohol Interaction

Increased CNS depression; avoid alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to mirtazapine; concurrent use with MAOIs or within 14 days of MAOI discontinuation.

📊 Monitoring Parameters

Mood, suicidal ideation, liver function tests, white blood cell count (rare agranulocytosis).

🤱 Lactation Safety

Excreted in breast milk; use with caution.

💊 Overdose Management

Symptoms: sedation, confusion, tachycardia; treatment: supportive care, activated charcoal, gastric lavage if recent.

⏰ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

🔗 View Profile

🔄 Substitutes for agipine 7.5mg tablet

View All

Alternative brands with exact same active ingredient (Mirtazapine (7.5mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.