Agipine 7.5mg Tablet (Mirtazapine): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- New or worsening thoughts of suicide or self-harm
- Agitation, hallucinations, rapid heart rate, fever, muscle stiffness, or confusion (signs of serotonin syndrome)
- Severe allergic reaction: rash, itching, swelling of face, lips, tongue, or throat, difficulty breathing
- Fainting, dizziness, or palpitations (possible heart rhythm changes)
- Severe headache, confusion, seizures, or weakness (possible low sodium levels)
- Yellowing of skin or eyes, dark urine, or severe abdominal pain (possible liver problems)
- Unusual bleeding or bruising
- Fever, sore throat, or mouth ulcers (possible blood disorder)
If experiencing severe symptoms, call emergency services immediately.
What is agipine 7.5mg tablet used for?
This medicine contains mirtazapine 7.5 mg, an antidepressant used to treat major depressive disorder. It works by blocking certain receptors in the brain to improve mood, sleep, and appetite. It is usually taken at bedtime due to its sedative effects. Do not stop this medicine suddenly without consulting your doctor.
- Generic Name: Mirtazapine
- Manufacturer: AGM Biotec
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 agipine 7.5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मिर्टाज़ापाइन 7.5 मिलीग्राम की गोली है, जिसका उपयोग अवसाद (डिप्रेशन) के इलाज के लिए किया जाता है। यह मूड को बेहतर बनाने, नींद में सुधार करने और भूख बढ़ाने में मदद करती है। यह दवा आमतौर पर रात में सोने से पहले ली जाती है क्योंकि यह नींद ला सकती है। इस दवा को डॉक्टर की सलाह के बिना अचानक बंद न करें। यह दवा हर किसी के लिए नहीं है। जिन लोगों को मिर्टाज़ापाइन से एलर्जी है या जो मोनोमाइन ऑक्सीडेज इनहिबिटर (MAOI) ले रहे हैं, उन्हें यह दवा नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, भूख बढ़ना, वजन बढ़ना, मुँह सूखना, कब्ज और चक्कर आना शामिल हैं। ये प्रभाव आमतौर पर शुरुआत में होते हैं और कुछ हफ्तों में कम हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, सेरोटोनिन सिंड्रोम और दिल की धड़कन में गड़बड़ी हो सकती है। अगर आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से दवा की मात्रा न बदलें और न ही अचानक बंद करें। यह दवा नींद ला सकती है, इसलिए जब तक आपको इसका असर पता न चले, गाड़ी न चलाएं और मशीनरी न चलाएं। इस दवा के साथ शराब न लें। अगर आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। इस दवा को बच्चों की पहुंच से दूर रखें।
💊 agipine 7.5mg tablet Uses & Benefits
- [{"condition":"Major depressive disorder","description":"This medicine is approved for the treatment of major depressive disorder in adults.
- It helps improve mood, sleep, appetite, and energy levels.","evidence":"Well-established"},{"condition":"Depression with insomnia","description":"Because of its sedating properties, this medicine is often helpful for people whose depression includes difficulty falling or staying asleep.","evidence":"Well-established"},{"condition":"Depression with poor appetite and weight loss","description":"This medicine can stimulate appetite and promote weight gain, which may benefit underweight patients with depression.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Insomnia","description":"Low-dose mirtazapine is sometimes prescribed off-label for short-term management of insomnia, especially when other treatments have failed.","evidence":"Limited"},{"condition":"Nausea and vomiting","description":"This medicine has been used off-label to help with nausea and vomiting, particularly in palliative care settings.","evidence":"Limited"},{"condition":"Post-traumatic stress disorder (PTSD) nightmares","description":"Some clinicians use this medicine off-label to reduce the frequency and intensity of nightmares in PTSD.","evidence":"Limited"}]
Primary treatment for: Major depressive disorder
Also treats: Depression with insomnia, Depression with poor appetite, Depression with weight loss
📋 Drug Information
| Generic Name(s) | Mirtazapine |
| Brand Name | Agipine |
| Manufacturer | AGM Biotec |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Noradrenergic and specific serotonergic antidepressants (NASSAs) |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C (59°F to 86°F). Keep it in a dry place, away from moisture and direct sunlight. Do not refrigerate or freeze. Keep this medicine out of the reach of children and pets. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture. Check the expiry date on the packaging before use. Do not use this medicine after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking specific serotonin and noradrenaline receptors in the brain. It is an antagonist at central presynaptic alpha-2 adrenergic inhibitory autoreceptors and heteroreceptors, which increases the release of noradrenaline and serotonin. It also blocks serotonin 5-HT2 and 5-HT3 receptors, which contributes to its antidepressant and sleep-promoting effects. Additionally, it is a potent antagonist of histamine H1 receptors, which explains its sedative and appetite-stimulating properties. This medicine has little effect on serotonin reuptake, unlike SSRIs.
Mechanism Steps
💡 How to Take agipine 7.5mg tablet
Strength: This medicine is available as an immediate-release tablet containing 7.5 mg of mirtazapine.
Dosage Information
| Adult Dosage | The usual starting dose of this medicine for adults with major depressive disorder is 15 mg once daily at bedtime. However, this 7.5 mg tablet may be used as a starting dose or for specific situations as determined by your doctor. The dose may be increased gradually up to a maximum of 45 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to treatment. Do not change your dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for use in children under 18 years of age due to an increased risk of suicidal thoughts and behaviors. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and low sodium levels. The starting dose may be lower, and dose increases should be made cautiously. Dose must be individualized by a qualified clinician based on renal and hepatic function and overall health status. |
| Renal Impairment | In patients with impaired kidney function, the clearance of this medicine may be reduced. Dose adjustment may be necessary. Consult your doctor for individualized dosing. |
| Hepatic Impairment | In patients with impaired liver function, the clearance of this medicine may be reduced. Dose adjustment may be necessary. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine is 45 mg per day. Doses above 45 mg per day have not been shown to be more effective and may increase the risk of side effects. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of agipine 7.5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Tramadol | Major | |
| Triptans | Major | |
| Linezolid | Major | |
| Methylene blue | Major | |
| Fluoxetine | Moderate | |
| Ketoconazole | Moderate | |
| Rifampin | Moderate | |
| Diazepam | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Tramadol
- Triptans (e.g., sumatriptan)
- Linezolid
- Methylene blue
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, bupropion)
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
- Benzodiazepines (e.g., diazepam, lorazepam)
- Alcohol
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the sedative effects of this medicine and impair your ability to drive or operate machinery. It may also worsen depression.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to mirtazapine or any component of the formulation","Concurrent use with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping an MAOI","Use in children under 18 years of age is not recommended due to increased risk of suicidal thoughts"]
⚠️ Warnings & Precautions
["This medicine may increase the risk of suicidal thoughts and behaviors, especially in children, adolescents, and young adults. Monitor closely for worsening depression or unusual changes in behavior.","This medicine can cause drowsiness and impair your ability to drive or operate machinery. Avoid these activities until you know how it affects you.","Do not stop this medicine abruptly, as withdrawal symptoms may occur. Taper gradually under medical supervision.","This medicine may cause weight gain and increased appetite. Monitor your weight and discuss with your doctor if concerned.","Use with caution in patients with bipolar disorder, as it may precipitate a manic episode.","Use with caution in patients with liver or kidney disease. Dose adjustment may be needed.","This medicine may cause low sodium levels (hyponatremia), especially in elderly patients. Monitor for signs such as confusion, headache, and weakness.","This medicine may increase the risk of serotonin syndrome when used with other serotonergic drugs. Monitor for symptoms."]
🤱 Lactation Safety
This medicine is excreted in breast milk. There are limited data on its effects on breastfed infants. Some infants may experience sedation, poor feeding, or weight gain. Consult your doctor to weigh the benefits of breastfeeding against the potential risks to the infant.
💊 Overdose Management
Overdose of this medicine may cause drowsiness, disorientation, tachycardia, and mild hypertension or hypotension. In severe cases, it can lead to respiratory depression, coma, and death. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be used if the overdose is recent. Monitor vital signs and cardiac rhythm.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop it suddenly on your own. This medicine can make you drowsy, so avoid driving or operating heavy machinery until you know how it affects you. Avoid alcohol while taking this medicine because it can increase drowsiness and impair your judgment. Tell your doctor about all other medicines, supplements, and herbal products you take, especially MAOIs, tramadol, and triptans. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before taking this medicine. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight. If you miss a dose, follow your doctor's instructions or the missed dose guidance provided with this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and low sodium levels. The starting dose may be lower, and dose increases should be made cautiously. Regular monitoring of kidney function and electrolytes is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, talk to your doctor before taking this medicine. Untreated depression can be harmful to both mother and baby. Your doctor will help you weigh the risks and benefits of continuing this medicine during pregnancy.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. This medicine may interact with anesthetic agents and increase sedation. Your doctor may advise you to stop this medicine temporarily before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine can cause dry mouth, which may increase the risk of dental problems. It may also interact with sedatives used in dentistry.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness. Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you. If you feel dizzy or faint during exercise, stop and rest.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, which may affect your ability to drive or operate machinery. It is best to take it at bedtime. You may need to adjust your work schedule if you experience morning drowsiness. Discuss with your employer if you need accommodations. Avoid operating heavy machinery until you know how this medicine affects you.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you need to stop, your doctor will gradually reduce your dose to prevent withdrawal symptoms. If you experience severe side effects or allergic reactions, seek immediate medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to weight gain, increased appetite, and metabolic changes. Regular monitoring of weight, blood sugar, and lipid levels may be necessary. Some patients may experience sexual dysfunction, though this is less common than with SSRIs. Periodic assessment of liver and kidney function may be advised. Do not stop this medicine without consulting your doctor, as withdrawal symptoms can occur.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
CBT is an effective non-drug treatment for depression and can be used alone or in combination with medication.
Evidence: Well-establishedExercise has been shown to improve mood and reduce symptoms of depression.
Evidence: Well-establishedThese practices can help reduce stress and improve emotional well-being.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are feeling unwell, consult your doctor before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. If crossing time zones, consult your doctor about adjusting the timing of your dose. Store this medicine at room temperature and away from direct sunlight. Check the customs regulations of your destination country regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine may help with sleep within a few days, but its antidepressant effects usually take 1 to 4 weeks to become noticeable. Full benefits may take 6 to 8 weeks.
A: This medicine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Discuss with your doctor.
A: Common side effects include drowsiness, increased appetite, weight gain, dry mouth, constipation, and dizziness.
A: No, avoid alcohol as it can increase sedation and impair your judgment.
A: Take the missed dose as soon as you remember, but skip it if it's almost time for your next dose. Do not double dose.
A: No, stopping suddenly can cause withdrawal symptoms. Always taper gradually under medical supervision.
🤔 Common Patient Concerns
🔄 Substitutes for agipine 7.5mg tablet
View AllAlternative brands with exact same active ingredient:
-
mirise 7.5mg tabletSunrise Remedies Pvt Ltd ₹32.81 30.2% CHEAPER
-
Mira 7.5mg TabletZoic Lifesciences ₹32.90 30% CHEAPER
-
miramind 7.5mg tabletTorrent Pharmaceuticals Ltd ₹33.00 29.8% CHEAPER
-
mizhra 7.5 mg tabletUSV Ltd ₹33.47 28.8% CHEAPER
-
mitrapil 7.5mg tabletPsychotropics India Ltd ₹34.66 26.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is only for sleep.
Fact: This medicine is an antidepressant used to treat depression. It can help with sleep, but its main purpose is to improve mood. - Myth: This medicine works immediately.
Fact: This medicine may help with sleep within a few days, but its antidepressant effects usually take 1 to 4 weeks to become noticeable. - Myth: This medicine is safe to stop suddenly.
Fact: Stopping this medicine suddenly can cause withdrawal symptoms. Always taper gradually under medical supervision. - Myth: This medicine is addictive.
Fact: This medicine is not considered addictive in the same way as opioids or benzodiazepines, but it can cause dependence and withdrawal symptoms if stopped abruptly.
🔄 Alternative Options
Generic Alternatives
- Mirtazapine 7.5 mg tablet
Brand Alternatives
- Agipine 7.5mg Tablet