afmed 20mg tablet - Uses, Price, Side Effects & Substitutes
What is afmed 20mg tablet used for?
Afzeta 30mg Tablet (Afatinib) is used to treat ANTI NEOPLASTICS. It contains Afatinib dimaleate (20mg), which Irreversible inhibitor of ErbB family of tyrosine kinases (EGFR, HER2, ErbB3, Er. Always consult your doctor before use. Take as prescribed.
- Generic Name: Afatinib
- Manufacturer: Medicamen Biotech Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ afmed 20mg tablet Uses & Benefits
First-line treatment of EGFR mutation-positive non-small cell lung cancer (NSCLC)
Off-label uses: Head and neck cancer, breast cancer (HER2-positive), other EGFR-driven tumors
๐ Drug Information
| Generic Name(s) | Afatinib |
| Brand Name | Afzeta 30mg Tablet |
| Manufacturer | Medicamen Biotech Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Tyrosine kinase inhibitors |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Irreversible inhibitor of ErbB family of tyrosine kinases (EGFR, HER2, ErbB3, ErbB4)
Mechanism Steps
๐ก How to Take afmed 20mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of afmed 20mg tablet
โ Common Side Effects
- Diarrhea
- Rash
- Stomatitis
- Paronychia
- Decreased appetite
- Fatigue
๐จ Serious Side Effects
- Interstitial lung disease
- Severe hepatotoxicity
- QT prolongation
- Severe diarrhea with dehydration
- Bullous skin reactions
โ ๏ธ Rare Side Effects
- Pancreatitis
- Nephrotic syndrome
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased afatinib exposure |
| Rifampin | Major | Decreased afatinib exposure |
| Digoxin | Moderate | Increased digoxin levels |
| Warfarin | Moderate | Increased INR |
| Grapefruit juice | Minor | Possible increased afatinib levels |
๐จ Major Interactions
- Ketoconazole
- Rifampin
- P-glycoprotein inhibitors
- CYP3A4 inducers
โก Moderate Interactions
- Digoxin
- Warfarin
- Statins
- Antacids
โน๏ธ Minor Interactions
- Grapefruit juice
- Caffeine
๐ฝ๏ธ Food Interactions
High-fat meals reduce absorption; take on empty stomach
๐ท Alcohol Interaction
Avoid alcohol due to hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Pregnancy, severe hepatic impairment, hypersensitivity to afatinib
๐ Monitoring Parameters
Liver function tests, renal function, ECG, electrolytes, skin reactions, diarrhea
๐คฑ Lactation Safety
Not recommended; excreted in animal milk, unknown in humans
๐ Overdose Management
No specific antidote; supportive care, monitor for adverse effects
โฐ Missed Dose
If missed, take as soon as remembered unless <12 hours to next dose; do not double
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for afmed 20mg tablet
View AllAlternative brands with exact same active ingredient (Afatinib dimaleate (20mg)):
-
afanat 20 tabletNatco Pharma Ltd โน2,906.00 1.3% COSTLIER
-
xovoltib 20mg tabletBoehringer Ingelheim โน51,476.25 1694.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.