afenasol 0.5mg tablet - Flupenthixol (0.5mg) medicine

Afenasol 0.5mg Tablet - Uses, Price, Side Effects

No reviews yet
๐Ÿญ Asvins Lifecare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is afenasol 0.5mg tablet used for?

Afenasol 0.5mg Tablet contains Flupenthixol, a thioxanthene antipsychotic used to treat schizophrenia and depression. It works by blocking dopamine and serotonin receptors in the brain, helping to improve mood and reduce psychotic symptoms. It is typically taken once or twice daily as prescribed by a doctor.

  • Generic Name: Flupenthixol
  • Manufacturer: Asvins Lifecare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š afenasol 0.5mg tablet Uses & Benefits

Schizophrenia, depression with anxiety, anxiety disorders, maintenance of bipolar disorder.

Off-label uses: Nausea and vomiting, agitation, dementia-related psychosis.

๐Ÿ“‹ Drug Information

Generic Name(s)Flupenthixol
Brand NameAnxiset 0.5 Tablet
ManufacturerAsvins Lifecare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassTypical Antipsychotics
Route of AdministrationOral (tablets), intramuscular (depot injection).
StorageStore at 20-25ยฐC, protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally, peak plasma concentration reached in 3-6 hours.
DistributionWidely distributed, crosses blood-brain barrier, volume of distribution 14 L/kg.
Protein Binding>99% bound to plasma proteins (albumin).
MetabolismExtensively metabolized in liver via CYP2D6 and other pathways.
Half-Life35 hours (oral), 19-39 hours (IM depot).
ExcretionPrimarily excreted in feces (via bile) and urine as metabolites.
Bioavailability40-50% (oral) due to first-pass metabolism.
Onset of ActionWithin 1-2 hours for oral, 24-72 hours for IM depot.
Peak Plasma Time3-6 hours (oral).
Duration of Action2-3 weeks for depot, 24 hours for oral.

How It Works

Blocks dopamine D1 and D2 receptors, also blocks serotonin 5-HT2A receptors.

Mechanism Steps

1Flupenthixol crosses the blood-brain barrier.
2Binds to dopamine D1 and D2 receptors in the brain.
3Blocks dopamine binding, reducing dopaminergic neurotransmission.

๐Ÿ’ก How to Take afenasol 0.5mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of afenasol 0.5mg tablet

โœ… Common Side Effects

  • Drowsiness
  • Dry mouth
  • Constipation
  • Weight gain
  • Extrapyramidal symptoms
  • Akathisia
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Tardive dyskinesia
  • Neuroleptic malignant syndrome
  • Seizures
  • QT prolongation
  • Agranulocytosis
  • Jaundice

โš ๏ธ Rare Side Effects

  • Photosensitivity
  • Galactorrhea
  • Gynecomastia
  • Impotence
  • Priapism
  • Lupus-like syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Hypertensive crisis
Anticholinergics Moderate Increased anticholinergic effects
Alcohol Moderate Increased CNS depression

๐Ÿšจ Major Interactions

  • MAOIs
  • Linezolid
  • Methylene blue
  • Other antipsychotics
  • Levodopa
  • Dopamine agonists

โšก Moderate Interactions

  • CNS depressants
  • Alcohol
  • Anticholinergics
  • Antihypertensives
  • Lithium

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Indomethacin
  • Propranolol

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase plasma levels.

๐Ÿท Alcohol Interaction

Increased CNS depression and sedation.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity, comatose states, CNS depression, bone marrow depression, pheochromocytoma, severe liver/renal impairment.

๐Ÿ“Š Monitoring Parameters

Blood pressure, heart rate, ECG, liver function tests, renal function, blood counts, extrapyramidal symptoms.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; avoid breastfeeding or monitor infant for sedation.

๐Ÿ’Š Overdose Management

Supportive care, gastric lavage, activated charcoal, monitor ECG, treat hypotension with IV fluids and vasopressors.

โฐ Missed Dose

Take as soon as remembered unless near next dose; skip missed dose if close to next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for afenasol 0.5mg tablet

View All

Alternative brands with exact same active ingredient (Flupenthixol (0.5mg)):

Medical Note: Always consult your doctor before switching medications.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory
SaathiMed App
SaathiMed App Consult doctors & order medicines faster
Install