aeroace-t4 tablet - Aceclofenac (100mg) + Thiocolchicoside (4mg) medicine

aeroace-t4 tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Doctomed ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is aeroace-t4 tablet used for?

Aldigesic TH 100mg/4mg Tablet (Aceclofenac + Thiocolchicoside) is used to treat PAIN ANALGESICS. It contains Aceclofenac (100mg) + Thiocolchicoside (4mg), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Thiocolc. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Aceclofenac + Thiocolchicoside
  • Manufacturer: Doctomed
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š aeroace-t4 tablet Uses & Benefits

Acute musculoskeletal pain, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle spasms

Off-label uses: Postoperative pain, dental pain, dysmenorrhea

๐Ÿ“‹ Drug Information

Generic Name(s)Aceclofenac + Thiocolchicoside
Brand NameAldigesic TH 100mg/4mg Tablet
ManufacturerDoctomed
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Muscle Relaxant
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture and light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in tissues
Protein BindingAceclofenac: >99% bound to plasma proteins; Thiocolchicoside: ~13% bound
MetabolismAceclofenac: Hepatic via CYP2C9 to diclofenac; Thiocolchicoside: Hepatic glucuronidation
Half-LifeAceclofenac: ~4 hours; Thiocolchicoside: ~7 hours
ExcretionAceclofenac: Renal (70-80% as metabolites); Thiocolchicoside: Renal (70% as glucuronide) and fecal
BioavailabilityAceclofenac: ~100%; Thiocolchicoside: ~25%
Onset of ActionAceclofenac: 30-60 minutes; Thiocolchicoside: 1-2 hours
Peak Plasma TimeAceclofenac: 1-3 hours; Thiocolchicoside: 1-2 hours
Duration of ActionAceclofenac: 12 hours; Thiocolchicoside: 24 hours

How It Works

Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Thiocolchicoside acts as a GABA-A receptor agonist and glycine receptor agonist, producing muscle relaxation

Mechanism Steps

1Aceclofenac inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis from arachidonic acid.
2Decreased prostaglandins lead to reduced inflammation, pain, and fever.
3Thiocolchicoside binds to GABA-A receptors and glycine receptors in the spinal cord and brainstem.

๐Ÿ’ก How to Take aeroace-t4 tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of aeroace-t4 tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Dizziness
  • Headache
  • Somnolence
  • Abdominal pain
  • Dyspepsia

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Hepatotoxicity
  • Nephrotoxicity
  • Cardiovascular events
  • Stevens-Johnson syndrome
  • Anaphylaxis
  • Bone marrow suppression

โš ๏ธ Rare Side Effects

  • Pancreatitis
  • Hearing loss
  • Tinnitus
  • Aseptic meningitis
  • Photosensitivity
  • Agranulocytosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Lithium Major Increased lithium toxicity
Methotrexate Major Increased methotrexate toxicity
Aspirin Major Increased GI ulceration risk
Corticosteroids Major Increased GI bleeding risk
Diuretics Major Reduced diuretic efficacy
ACE inhibitors Major Reduced antihypertensive effect
Cyclosporine Major Increased nephrotoxicity
SSRIs Moderate Increased bleeding risk
Alcohol Moderate Increased GI bleeding and hepatotoxicity

๐Ÿšจ Major Interactions

  • Warfarin
  • Lithium
  • Methotrexate
  • Anticoagulants
  • Aspirin
  • Corticosteroids
  • Diuretics
  • ACE inhibitors
  • Cyclosporine
  • Tacrolimus

โšก Moderate Interactions

  • SSRIs
  • SNRIs
  • Antiplatelet agents
  • Pentoxifylline
  • Zidovudine
  • Pemetrexed

โ„น๏ธ Minor Interactions

  • Beta-blockers
  • Digoxin
  • Phenytoin
  • Sulfonylureas

๐Ÿฝ๏ธ Food Interactions

May be taken with food to reduce GI upset; avoid alcohol

๐Ÿท Alcohol Interaction

Increased risk of GI bleeding and hepatotoxicity

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, active peptic ulcer, bleeding disorders, severe renal/hepatic impairment, pregnancy, lactation, children <18 years, history of asthma, CVS disease

๐Ÿ“Š Monitoring Parameters

Liver function, renal function, CBC, blood pressure, signs of GI bleeding

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage, activated charcoal; monitor for GI bleeding, renal function, CNS depression

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

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