Anaflam TH 8 Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is aefen pth 8mg/100mg/325mg tablet used for?
This medicine is a combination of thiocolchicoside (a muscle relaxant) and aceclofenac (an anti-inflammatory pain reliever) used for short-term relief of painful muscle spasms and musculoskeletal pain. It is taken orally with food, usually one tablet once or twice daily, as prescribed by a doctor.
- Generic Name: Thiocolchicoside + Aceclofenac
- Manufacturer: Sapson Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 aefen pth 8mg/100mg/325mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा थायोकोल्चिकोसाइड 8 मिलीग्राम और एसीक्लोफेनाक 100 मिलीग्राम का संयोजन है। इसका उपयोग मांसपेशियों में ऐंठन, दर्द और सूजन के इलाज के लिए किया जाता है, जैसे कि कमर दर्द, गर्दन दर्द, और चोट के बाद होने वाले दर्द में। यह दवा मांसपेशियों को आराम देती है और दर्द को कम करती है। इसे डॉक्टर की सलाह के अनुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, दस्त, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, और एलर्जी प्रतिक्रिया हो सकती है। यदि आपको काला मल, खून की उल्टी, तेज पेट दर्द, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब और अन्य दर्द निवारक दवाओं का सेवन न करें। यदि आपको चक्कर आते हैं तो वाहन न चलाएं। गर्भावस्था के दौरान इसका उपयोग न करें। बच्चों की पहुंच से दूर रखें।
💊 aefen pth 8mg/100mg/325mg tablet Uses & Benefits
[{"condition":"Acute low back pain with muscle spasm","description":"Relieves pain and reduces muscle spasm, improving mobility.","evidence":"Well-established"},{"condition":"Neck pain (cervical spondylosis) with spasm","description":"Reduces pain and stiffness associated with muscle spasm.","evidence":"Moderate"},{"condition":"Post-traumatic musculoskeletal pain","description":"Used after injuries like sprains or strains to reduce pain and inflammation.","evidence":"Moderate"},{"condition":"Post-operative pain and spasm","description":"May be prescribed short-term after surgery to manage pain and muscle spasm.","evidence":"Limited"}]
Off-label uses: [{"condition":"Tension-type headache","description":"Sometimes used off-label for tension headaches with muscle spasm.","evidence":"Limited"},{"condition":"Fibromyalgia","description":"Not standard, but occasionally prescribed for muscle pain in fibromyalgia.","evidence":"Insufficient"}]
Primary treatment for: Musculoskeletal pain with muscle spasm
Also treats: Acute low back pain, Neck pain, Post-traumatic pain, Post-operative pain
📋 Drug Information
| Generic Name(s) | Thiocolchicoside + Aceclofenac |
| Brand Name | Anaflam TH 4 Tablet |
| Manufacturer | Sapson Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Muscle Relaxant + NSAID |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits cyclooxygenase enzymes, reducing prostaglandin synthesis and thereby decreasing pain and inflammation. Thiocolchicoside is a centrally acting muscle relaxant that binds to GABA-A receptors and strychnine-sensitive glycine receptors in the spinal cord and brainstem, enhancing inhibitory neurotransmission and reducing muscle tone and spasm. Together, they provide relief from both pain and muscle spasm.
Mechanism Steps
💡 How to Take aefen pth 8mg/100mg/325mg tablet
Strength: Thiocolchicoside 8 mg + Aceclofenac 100 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally one to two times daily, preferably after meals. The exact dose and duration depend on the condition being treated, its severity, and the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects, especially gastrointestinal bleeding and kidney impairment. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose reduction may be necessary. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with liver impairment. Dose reduction may be necessary. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is two tablets (16 mg thiocolchicoside and 200 mg aceclofenac). Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of aefen pth 8mg/100mg/325mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Moderate | |
| Lithium | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor | |
| Aspirin | Minor | |
| Alcohol | Major |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
⚡ Moderate Interactions
- Antihypertensives (ACE inhibitors, ARBs, diuretics)
- Lithium
- SSRIs
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulcers, and drowsiness. It may also worsen liver toxicity.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to aceclofenac, thiocolchicoside, or any component","Active peptic ulcer or history of recurrent ulcers","Severe heart failure","Severe kidney disease","Severe liver disease","Third trimester of pregnancy","Children under 18 years (safety not established)","Use before coronary artery bypass graft surgery"]
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Avoid alcohol and other NSAIDs.","Do not drive if you feel dizzy or drowsy.","Use with caution in elderly patients.","Monitor liver and kidney function during long-term use.","Inform your doctor if you have asthma, bleeding disorders, or cardiovascular disease.","Do not use for more than 7 days without medical advice."]
🤱 Lactation Safety
Not established from the available information. Aceclofenac may pass into breast milk. Consult your doctor before use during breastfeeding.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, stomach pain, drowsiness, and kidney or liver damage. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Always take it with food or milk to reduce stomach irritation. Avoid alcohol and other NSAIDs while on this medicine. Inform your doctor if you have a history of stomach ulcers, kidney or liver problems, asthma, or bleeding disorders. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Use effective contraception during treatment and avoid use in the third trimester of pregnancy. Keep out of reach of children. Store at room temperature away from moisture and direct sunlight. Do not use this medicine for minor aches without medical advice.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor closely.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the third trimester. If you are planning pregnancy, consult your doctor to switch to a safer alternative.
🏥 Post-Surgery Considerations
May be prescribed short-term after surgery for pain and muscle spasm. Use only under medical supervision and for the shortest duration necessary.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may increase bleeding risk during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while experiencing muscle spasm. Gentle stretching and physiotherapy may be beneficial after acute pain subsides.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, affecting your ability to drive or operate machinery. Avoid such activities until you know how it affects you. Take rest and avoid prolonged sitting or standing.
🛑 When to Stop This Medicine
Stop taking this medicine if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or kidney problems. Do not stop abruptly without consulting your doctor if you have been on long-term therapy.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, and liver toxicity. Regular monitoring of liver and kidney function is advised. It is not recommended for extended use without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedMay help relieve muscle spasm and pain.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. Consult your doctor before any vaccination while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30 to 60 minutes after taking the tablet.
A: It is best taken with food or milk to reduce stomach upset.
A: Avoid taking other NSAIDs without consulting your doctor, as it may increase the risk of side effects.
🤔 Common Patient Concerns
🔄 Substitutes for aefen pth 8mg/100mg/325mg tablet
View AllAlternative brands with exact same active ingredient:
-
edoclof-max tabletEdmund Healthcare ₹32.81 86.8% CHEAPER
-
xynac th 100mg/8mg tabletArlak Biotech Pvt Ltd ₹67.50 72.8% CHEAPER
-
Thiochy A 100mg/8mg TabletMelody Healthcare Private Limited ₹92.81 62.6% CHEAPER
-
Thiodal 100mg/8mg TabletSapiens Labs Pvt Ltd ₹105.00 57.7% CHEAPER
-
thioceclo 100mg/8mg tablet srAristo Pharmaceuticals Pvt Ltd ₹128.30 48.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of pain.
Fact: It is specifically for musculoskeletal pain with muscle spasm and should not be used for all pain types. - Myth: It is safe to take long-term without monitoring.
Fact: Long-term use requires monitoring of liver and kidney function and is not recommended without medical supervision. - Myth: It can be taken on an empty stomach.
Fact: It should be taken with food to reduce stomach upset and risk of ulcers.
🔄 Alternative Options
Generic Alternatives
- Thiocolchicoside + Aceclofenac combination (generic)
Brand Alternatives
- Anaflam TH 8 Tablet