aece-dmr tablet - Chlorzoxazone (250mg) + Diclofenac (50mg) medicine

aece-dmr tablet

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🏭 Aadi Health Care 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

What is aece-dmr tablet used for?

This medicine contains Chlorzoxazone (250mg) + Diclofenac (50mg) and is used to treat PAIN ANALGESICS. Chlorzoxazone: Depresses CNS; Diclofenac: Inhibits COX-1/2. Always consult your doctor before use.

  • Generic Name: Chlorzoxazone + Diclofenac
  • Manufacturer: Aadi Health Care
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 aece-dmr tablet Uses & Benefits

Acute musculoskeletal pain, muscle spasms

Off-label uses: Chronic pain (not recommended)

📋 Drug Information

Generic Name(s)Chlorzoxazone + Diclofenac
Brand NameAche X Tablet
ManufacturerAadi Health Care
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassMuscle Relaxant + NSAID
Route of AdministrationOral
StorageStore at 20-25°C, protect from moisture
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely; crosses placenta
Protein BindingChlorzoxazone: 13-18%; Diclofenac: >99%
MetabolismChlorzoxazone: Hepatic (CYP2E1); Diclofenac: Hepatic (CYP2C9)
Half-LifeChlorzoxazone: 1-2 hrs; Diclofenac: 2 hrs
ExcretionUrine (metabolites)
BioavailabilityChlorzoxazone: ~100%; Diclofenac: ~50%
Onset of Action30-60 minutes
Peak Plasma Time1-2 hours
Duration of Action4-6 hours

How It Works

Chlorzoxazone: Depresses CNS; Diclofenac: Inhibits COX-1/2

Mechanism Steps

1Chlorzoxazone acts on CNS to depress reflexes and relax muscles
2Diclofenac inhibits cyclooxygenase (COX-1 and COX-2) enzymes
3COX inhibition reduces prostaglandin synthesis
4Decreased prostaglandins lead to reduced pain and inflammation

💡 How to Take aece-dmr tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of aece-dmr tablet

✅ Common Side Effects

Drowsiness
Dizziness
Nausea
Dyspepsia
Headache

🚨 Serious Side Effects

GI bleeding
Hepatotoxicity
Renal failure
Anaphylaxis

⚠️ Rare Side Effects

Blood dyscrasias
Stevens-Johnson syndrome
Pancreatitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased bleeding risk
Aspirin Major Increased GI ulceration risk
Lithium Major Increased lithium toxicity
Methotrexate Major Increased methotrexate toxicity
CYP2C9 inhibitors Major Increased diclofenac levels
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect
Anticoagulants Moderate Increased bleeding risk
Corticosteroids Moderate Increased GI ulceration risk
Antacids Minor Reduced absorption
Caffeine Minor Increased CNS stimulation

🚨 Major Interactions

  • Warfarin
  • Aspirin
  • Lithium
  • Methotrexate
  • CYP2C9 inhibitors

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • Corticosteroids

🍷 Alcohol Interaction

Increased hepatotoxicity risk

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, active GI bleeding, severe hepatic/renal impairment, history of asthma with NSAIDs, third trimester pregnancy

🤱 Lactation Safety

Not recommended; excreted in milk

💊 Overdose Management

Symptomatic and supportive; gastric lavage, activated charcoal

⏰ Missed Dose

Take as soon as remembered; skip if near next dose

🔄 Substitutes for aece-dmr tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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