adpep d tablet - Uses, Price, Side Effects & Substitutes
What is adpep d tablet used for?
Alera D 50 mg/10 mg Tablet (Diclofenac + Serratiopeptidase) is used to treat PAIN ANALGESICS. It contains Diclofenac (50mg) + Serratiopeptidase (10mg), which Diclofenac inhibits COX-1/COX-2, reducing prostaglandin synthesis; serratiopepti. Always consult your doctor before use. Take as prescribed.
- Generic Name: Diclofenac + Serratiopeptidase
- Manufacturer: Admac Pharma Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ adpep d tablet Uses & Benefits
Pain and inflammation in musculoskeletal disorders, dental pain, postoperative inflammation, dysmenorrhea.
Off-label uses: Acute gout, migraine, fever (diclofenac); chronic inflammation (serratiopeptidase).
๐ Drug Information
| Generic Name(s) | Diclofenac + Serratiopeptidase |
| Brand Name | Alera D 50 mg/10 mg Tablet |
| Manufacturer | Admac Pharma Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Proteolytic Enzyme |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Diclofenac inhibits COX-1/COX-2, reducing prostaglandin synthesis; serratiopeptidase hydrolyzes inflammatory mediators and reduces edema.
Mechanism Steps
๐ก How to Take adpep d tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of adpep d tablet
โ Common Side Effects
- Nausea
- Dyspepsia
- Abdominal pain
- Diarrhea
- Headache
- Dizziness
- Rash
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Renal failure
- Hepatotoxicity
- Cardiovascular thrombotic events
- Anaphylaxis
โ ๏ธ Rare Side Effects
- Pancreatitis
- Aseptic meningitis
- Blood dyscrasias
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Lithium | Major | Increased lithium toxicity |
| Methotrexate | Major | Increased methotrexate toxicity |
| ACE inhibitors | Major | Reduced antihypertensive effect, increased renal impairment risk |
| Diuretics | Major | Reduced diuretic effect, increased nephrotoxicity |
| Aspirin | Major | Increased GI ulceration risk |
| Other NSAIDs | Major | Additive adverse effects |
๐จ Major Interactions
- Warfarin
- Lithium
- Methotrexate
- ACE inhibitors
- Diuretics
- Aspirin
- Other NSAIDs
โก Moderate Interactions
- Anticoagulants
- Antiplatelets
- SSRIs
- Corticosteroids
- Cyclosporine
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
- Digoxin
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid high-fat meals.
๐ท Alcohol Interaction
Increased risk of GI bleeding and hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active GI bleeding, severe renal/hepatic impairment, history of asthma with NSAIDs, third trimester pregnancy, coronary artery bypass graft surgery.
๐ Monitoring Parameters
Renal function, hepatic function, blood pressure, signs of GI bleeding.
๐คฑ Lactation Safety
Not recommended; diclofenac excreted in breast milk.
๐ Overdose Management
Symptomatic and supportive; gastric lavage, activated charcoal; no specific antidote.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double.