adospas tablet - Uses, Price, Side Effects & Substitutes
What is adospas tablet used for?
Almefkem Spas 10mg/250mg Tablet (Dicyclomine + Mefenamic Acid) is used to treat PAIN ANALGESICS. It contains Dicyclomine (10mg) + Mefenamic Acid (250mg), which Dicyclomine: Antimuscarinic, relaxes smooth muscle; Mefenamic Acid: Inhibits COX. Always consult your doctor before use. Take as prescribed.
- Generic Name: Dicyclomine + Mefenamic Acid
- Manufacturer: Adoc Pharma
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ adospas tablet Uses & Benefits
Treatment of abdominal cramps, dysmenorrhea, and other smooth muscle spasms associated with pain
Off-label uses: Renal colic, biliary colic, migraine (limited evidence)
๐ Drug Information
| Generic Name(s) | Dicyclomine + Mefenamic Acid |
| Brand Name | Almefkem Spas 10mg/250mg Tablet |
| Manufacturer | Adoc Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Antispasmodic + NSAID |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Dicyclomine: Antimuscarinic, relaxes smooth muscle; Mefenamic Acid: Inhibits COX-1 and COX-2, reducing prostaglandin synthesis
Mechanism Steps
๐ก How to Take adospas tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of adospas tablet
โ Common Side Effects
- Dizziness
- Dry mouth
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Drowsiness
- Blurred vision
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Renal failure
- Hepatotoxicity
- Anaphylaxis
- Stevens-Johnson syndrome
- Seizures
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Pancreatitis
- Interstitial nephritis
- Aseptic meningitis
- Photosensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Aspirin | Major | Increased risk of GI ulceration and bleeding |
| Methotrexate | Major | Increased methotrexate toxicity |
| Lithium | Major | Increased lithium levels and toxicity |
| ACE inhibitors | Major | Reduced antihypertensive effect; increased nephrotoxicity |
| Diuretics | Major | Reduced diuretic effect; increased nephrotoxicity |
| Anticoagulants | Major | Increased bleeding risk |
| Corticosteroids | Major | Increased risk of GI ulceration |
| Antihypertensives | Moderate | Reduced antihypertensive effect |
| SSRIs | Moderate | Increased bleeding risk |
| Antidiabetic agents | Moderate | Enhanced hypoglycemic effect |
| Digoxin | Moderate | Increased digoxin levels |
| Phenytoin | Moderate | Increased phenytoin levels |
| Cyclosporine | Moderate | Increased nephrotoxicity |
| Antacids | Minor | Reduced absorption of mefenamic acid |
| Cholestyramine | Minor | Reduced absorption of mefenamic acid |
| Cimetidine | Minor | Increased mefenamic acid levels |
๐จ Major Interactions
- Warfarin
- Aspirin
- Methotrexate
- Lithium
- ACE inhibitors
- Diuretics
- Anticoagulants
- Corticosteroids
โก Moderate Interactions
- Antihypertensives
- SSRIs
- Antidiabetic agents
- Digoxin
- Phenytoin
- Cyclosporine
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
- Cimetidine
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid alcohol
๐ท Alcohol Interaction
Increased risk of GI bleeding and hepatotoxicity
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active GI bleeding, peptic ulcer disease, severe renal/hepatic impairment, history of asthma, third trimester pregnancy, children <6 months
๐ Monitoring Parameters
Renal function, hepatic function, CBC, signs of GI bleeding, blood pressure
๐คฑ Lactation Safety
Use with caution; may pass into breast milk
๐ Overdose Management
Symptomatic and supportive; induce emesis or gastric lavage; monitor for CNS depression, seizures, arrhythmias
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose