Adnil 5mg Tablet (Glibenclamide) - Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe hypoglycemia with confusion, seizures, or loss of consciousness
- Yellowing of skin or eyes (jaundice)
- Dark urine or pale stools
- Severe abdominal pain
- Unusual bleeding or bruising
- Fever with sore throat or mouth ulcers
- Swelling of face, lips, or throat or difficulty breathing
If experiencing severe symptoms, call emergency services immediately.
What is adnil 5mg tablet used for?
This medicine contains Glibenclamide 5mg, a sulfonylurea used to treat type 2 diabetes by stimulating insulin release from the pancreas. It is taken orally with meals, and the dose is individualized by a doctor.
- Generic Name: Glibenclamide
- Manufacturer: Globela Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 adnil 5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ग्लाइबेनक्लामाइड 5 मिलीग्राम की एक गोली है जिसका उपयोग टाइप 2 डायबिटीज (मधुमेह) में रक्त शर्करा को नियंत्रित करने के लिए किया जाता है। यह अग्न्याशय से इंसुलिन निकालने में मदद करती है। इसे भोजन के साथ लेना चाहिए। यह दवा डॉक्टर के परामर्श के बिना शुरू या बंद नहीं करनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में कम रक्त शर्करा (हाइपोग्लाइसीमिया), जी मिचलाना, पेट में हल्की परेशानी और त्वचा पर दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर हाइपोग्लाइसीमिया, एनीमिया और लीवर की समस्या शामिल हो सकती है। यदि आपको पसीना, कंपकंपी, चक्कर या भ्रम महसूस हो तो तुरंत मीठा खाएं और डॉक्टर को बताएं।
सुरक्षा सलाह: इस दवा को हमेशा भोजन के साथ या तुरंत बाद लें। कभी भी भोजन न छोड़ें। अपने साथ हमेशा ग्लूकोज या मिठाई रखें। शराब से बचें क्योंकि इससे रक्त शर्करा खतरनाक रूप से गिर सकती है। नियमित रूप से रक्त शर्करा की जांच करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर को सूचित करें। दवा को बच्चों की पहुंच से दूर रखें।
💊 adnil 5mg tablet Uses & Benefits
[{"condition":"Type 2 diabetes mellitus","description":"Used as an adjunct to diet and exercise to improve blood glucose control in adults with type 2 diabetes.","evidence":"Well-established"},{"condition":"Secondary diabetes due to pancreatic disease","description":"Sometimes used when other oral agents are not suitable, but only under specialist supervision.","evidence":"Limited"}]
Off-label uses: [{"condition":"Gestational diabetes","description":"Not routinely recommended; may be considered only if insulin is not feasible and under close specialist care.","evidence":"Limited"}]
Primary treatment for: Type 2 diabetes mellitus
Also treats: Secondary diabetes due to pancreatic disease
📋 Drug Information
| Generic Name(s) | Glibenclamide |
| Brand Name | Adnil 5mg Tablet |
| Manufacturer | Globela Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Sulfonylureas (Insulin Secretogogues) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine binds to specific receptors on pancreatic beta cells and closes ATP-sensitive potassium channels. This leads to depolarization of the cell membrane, opening of voltage-gated calcium channels, and influx of calcium. The rise in intracellular calcium triggers the release of insulin from preformed granules. Additionally, this medicine may increase the sensitivity of peripheral tissues to insulin. The overall effect is a reduction in blood glucose levels.
Mechanism Steps
💡 How to Take adnil 5mg tablet
Strength: Glibenclamide 5mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual starting dose of this medicine is 2.5 to 5 mg once daily, taken with breakfast or the first main meal. The dose may be increased gradually based on blood glucose response, up to a maximum of 20 mg per day. Doses above 10 mg per day may be divided. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the hypoglycemic effects of this medicine. Start with a low dose and titrate slowly. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in renal impairment. Dose reduction may be necessary. Contraindicated in severe renal impairment. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | Use with caution in hepatic impairment. Dose reduction may be necessary. Contraindicated in severe hepatic impairment. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | 20 mg per day |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of adnil 5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Beta-blockers | Major | |
| Fluconazole | Major | |
| Warfarin | Major | |
| Thiazide diuretics | Moderate | |
| Corticosteroids | Moderate | |
| ACE inhibitors | Moderate | |
| Alcohol | Moderate | |
| NSAIDs | Minor |
🚨 Major Interactions
- Beta-blockers
- Fluconazole
- Warfarin
⚡ Moderate Interactions
- Diuretics (thiazides)
- Corticosteroids
- ACE inhibitors
🍷 Alcohol Interaction
Alcohol can increase the risk of severe hypoglycemia and may cause a disulfiram-like reaction with flushing, nausea, and vomiting. It is best to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe renal impairment","Severe hepatic impairment","Known hypersensitivity to glibenclamide or other sulfonylureas","Pregnancy and breastfeeding"]
⚠️ Warnings & Precautions
["Risk of hypoglycemia, especially with irregular meals or alcohol.","May cause weight gain.","Use with caution in elderly patients and those with renal or hepatic impairment.","May increase cardiovascular risk in some patients.","Not recommended for use in children.","Avoid in patients with glucose-6-phosphate dehydrogenase deficiency due to risk of hemolytic anemia."]
🤱 Lactation Safety
This medicine is excreted in breast milk and may cause hypoglycemia in the nursing infant. Breastfeeding is not recommended while taking this medicine unless advised by a specialist.
💊 Overdose Management
Overdose can cause severe hypoglycemia. If overdose is suspected, seek emergency medical care immediately. Treatment includes intravenous glucose and close monitoring of blood glucose and vital signs.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if it is more than half the dosing interval away. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Always take this medicine with or immediately after a meal to reduce the risk of low blood sugar and stomach upset. Never skip meals while taking this medicine. Carry a source of fast-acting sugar such as glucose tablets or candy with you at all times. Check your blood sugar regularly as advised by your doctor. Avoid alcohol because it can cause dangerous drops in blood sugar. Tell your doctor about all other medicines you take, especially beta-blockers, diuretics, and other antidiabetic drugs. Do not drive or operate heavy machinery if you feel dizzy or shaky. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Keep this medicine out of reach of children and store it in its original packaging.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of hypoglycemia. Start with a low dose and monitor blood sugar closely. Dose adjustment may be needed based on renal function.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy. If you are planning pregnancy, consult your doctor to switch to a safer alternative, such as insulin.
🏥 Post-Surgery Considerations
Blood sugar control may be affected after surgery. Inform your surgeon and anesthesiologist about this medicine. Dose may need adjustment.
🦷 Dental Procedures
Inform your dentist about this medicine. Maintain good oral hygiene and monitor blood sugar before dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise can lower blood sugar. Check your blood sugar before exercising and carry a fast-acting sugar source. Avoid strenuous exercise if your blood sugar is low.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or shakiness due to low blood sugar, which can affect driving or operating machinery. Avoid these activities if you feel symptoms.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or your blood sugar is well controlled, your doctor may adjust or stop the medicine.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to weight gain and increased risk of hypoglycemia. It may also cause secondary failure over time, requiring addition of other antidiabetic agents. Regular monitoring of blood glucose, HbA1c, liver and kidney function is recommended.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise are essential for managing type 2 diabetes and can reduce the need for medication.
Evidence: Well-establishedMetformin, DPP-4 inhibitors, or SGLT2 inhibitors may be alternatives based on individual needs.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, infections can affect blood sugar control. Keep vaccinations up to date as advised by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid temperature extremes. Adjust dosing times if crossing time zones, but consult your doctor first. Carry extra doses in case of travel delays. Store away from direct sunlight and moisture.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood sugar within 30 to 60 minutes after taking it, but the full effect may take several days to weeks.
A: It may be used with caution and dose adjustment in mild to moderate kidney disease, but it is contraindicated in severe kidney disease.
A: If you miss a dose, take it as soon as you remember if it is more than half the dosing interval away. Otherwise, skip it and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for adnil 5mg tablet
View AllAlternative brands with exact same active ingredient:
-
betanase 5mg tabletCadila Pharmaceuticals Ltd ₹3.73 90.4% CHEAPER
-
gliconil 5mg tabletBiochem Pharmaceutical Industries ₹3.83 90.2% CHEAPER
-
codica 5mg tabletAbbott ₹4.41 88.7% CHEAPER
-
afdiex 5mg tabletCadila Pharmaceuticals Ltd ₹4.66 88.1% CHEAPER
-
davaindia glibenclamide 5mg tabletDavaindia Generic Pharmacy ₹5.00 87.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes.
Fact: This medicine helps control blood sugar but does not cure diabetes. It must be continued as prescribed. - Myth: This medicine can be taken without food.
Fact: This medicine should be taken with meals to reduce the risk of low blood sugar. - Myth: This medicine is safe for everyone with diabetes.
Fact: This medicine is not for type 1 diabetes or diabetic ketoacidosis and is contraindicated in pregnancy and severe kidney or liver disease.
🔄 Alternative Options
Generic Alternatives
- Glibenclamide 5mg tablet
Brand Alternatives
- Adnil 5mg tablet