adilan injection - Isoxsuprine (5mg/ml) medicine

Adilan Injection: Comprehensive Medicine Guide

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🏭 Albert David Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 27, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Limited
Reviewed by
SaathiMed Expert Panel | Oct 27, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Chest pain or irregular heartbeat
  • Severe dizziness or fainting
  • Severe headache with visual changes
  • Signs of severe allergic reaction such as rash and itching
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is adilan injection used for?

This medicine is an injectable vasodilator containing isoxsuprine, used to improve blood flow in peripheral vascular disease and occasionally to relax the uterus. It is administered by a healthcare professional.

  • Generic Name: Isoxsuprine (5mg/ml)
  • Manufacturer: Albert David Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 adilan injection के बारे में (Hindi Summary)

उपयोग: यह दवा एक इंजेक्शन है जिसमें आइसोक्ससुप्रीन नामक तत्व होता है। यह रक्त वाहिकाओं को फैलाकर रक्त के प्रवाह को बेहतर बनाती है। इसका उपयोग मुख्य रूप से पैरों और हाथों में रक्त संचार की कमी, ठंडक, सुन्नपन और ऐंठन जैसी समस्याओं में किया जाता है। कभी-कभी प्रसव को रोकने के लिए भी इसका उपयोग किया जाता है। यह दवा केवल डॉक्टर या नर्स द्वारा ही दी जानी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, दिल की धड़कन तेज होना, जी मिचलाना, उल्टी और चेहरे पर गर्मी लगना शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, सांस लेने में कठिनाई, सीने में दर्द और बहुत कम रक्तचाप हो सकता है। अगर ऐसा कुछ हो तो तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल स्वास्थ्य कर्मचारी द्वारा ही दी जानी चाहिए। खुद से इंजेक्शन न लगाएं। अगर आपको हृदय रोग, निम्न रक्तचाप, थायरॉइड या मधुमेह है तो डॉक्टर को बताएं। इस दवा को लेते समय शराब न पिएं। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चल जाए कि यह दवा आप पर कैसे असर करती है।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 adilan injection Uses & Benefits

[{"condition":"Peripheral vascular disease","description":"This medicine is used to improve blood flow in patients with narrowed blood vessels in the limbs, reducing symptoms like coldness, numbness, and cramping.","evidence":"Limited"},{"condition":"Cerebrovascular insufficiency","description":"It may be used to enhance blood circulation to the brain in certain conditions, although evidence is not robust.","evidence":"Limited"},{"condition":"Preterm labor (tocolytic)","description":"This medicine can relax uterine muscles and was historically used to delay premature labor, but safer alternatives are now preferred.","evidence":"Limited"}]

Off-label uses: [{"condition":"Raynaud's phenomenon","description":"Sometimes prescribed off-label to improve blood flow to fingers and toes in patients with Raynaud's phenomenon.","evidence":"Limited"},{"condition":"Intermittent claudication","description":"May be used off-label to improve walking distance in patients with intermittent claudication due to peripheral artery disease.","evidence":"Limited"}]

Primary treatment for: Peripheral vascular disease

Also treats: Cerebrovascular insufficiency, Preterm labor

📋 Drug Information

Generic Name(s)Isoxsuprine (5mg/ml)
Brand Nameadilan injection
ManufacturerAlbert David Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassBeta 2 agonist - Uterus
Route of AdministrationParenteral (intramuscular or intravenous)
StorageStore at room temperature (15-30°C). Protect from light. Do not freeze.
Shelf LifeNot established from the available information.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine only in a clinical setting with resuscitation equipment available.
2
Monitor blood pressure and heart rate before and after administration.
3
Ask patients about any history of heart disease or arrhythmias before prescribing.
4
Advise patients to avoid alcohol while receiving this medicine.
5
Instruct patients to report any signs of allergic reactions immediately.
6
Use with caution in elderly patients due to increased risk of hypotension.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Cold, painful extremities
This medicine is used to improve blood flow in peripheral vascular disease.
Likely Use
✅
Preterm labor contractions
This medicine may be used to relax the uterus.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is administered parenterally, so absorption is rapid and complete from the injection site.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionThe onset of action is within minutes after intravenous administration and within 10-30 minutes after intramuscular injection.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe duration of action is approximately 1-3 hours after intravenous administration and up to 4-6 hours after intramuscular injection.

How It Works

This medicine works by stimulating beta-2 adrenergic receptors on the smooth muscle cells of blood vessels. This stimulation leads to relaxation of the vascular smooth muscle, causing vasodilation and increased blood flow. It also has some effect on uterine smooth muscle, leading to relaxation.

Mechanism Steps

1
Binding to beta-2 receptors: This medicine binds to beta-2 adrenergic receptors located on the surface of smooth muscle cells in blood vessels and the uterus.
2
Activation of adenylate cyclase: Binding triggers the activation of the enzyme adenylate cyclase, which increases the production of cyclic AMP (cAMP) inside the cell.
3
Smooth muscle relaxation: Elevated cAMP levels lead to relaxation of the smooth muscle, resulting in vasodilation and uterine relaxation.

💡 How to Take adilan injection

Strength: Injection: 5 mg/ml

1This medicine is administered by a healthcare professional only.
2It is given as an intramuscular or intravenous injection.
3The injection site should be rotated if multiple doses are given.
4Do not self-administer.

Dosage Information

Adult DosageThe dosage of this medicine is individualized by a qualified clinician based on the indication, patient's age, weight, renal and hepatic function, and clinical response. It is typically administered intramuscularly or intravenously. Common adult doses range from 5 mg to 10 mg per administration, but the exact dose and frequency must be determined by the prescribing doctor. Do not self-administer.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially hypotension and dizziness. Dose should be individualized by a clinician.
Renal ImpairmentNot established from the available information. Use with caution in patients with renal impairment.
Hepatic ImpairmentNot established from the available information. Use with caution in patients with hepatic impairment.
Maximum Daily DoseNot established from the available information. Dose must be individualized by a qualified clinician.

⏰ What to Do If You Miss a Dose

📌 If you miss a scheduled dose
→ Contact your healthcare provider as soon as possible.
💡 Do not attempt to self-administer a double dose.

⚠️ Side Effects of adilan injection

✅ Common Side Effects

Dizziness (Common (5-10%))
Lie down and rest. Avoid sudden movements. Consult doctor if persistent.
Fast heartbeat (tachycardia) (Common (5-10%))
Report to your doctor if it feels uncomfortable or persists.
Nausea (Common (5-10%))
Take small sips of water. Inform your doctor if vomiting occurs.
Flushing (Common (5-10%))
This usually resolves on its own. Notify your doctor if it bothers you.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, throat, or difficulty breathing.
Chest pain or irregular heartbeat (Rare (<0.1%))
Stop the injection and seek immediate medical attention.
Severe hypotension (Rare (<0.1%))
Lie down and call for emergency medical assistance.

⚠️ Rare Side Effects

Blood dyscrasias
Report any unusual bleeding, bruising, or fatigue to your doctor.
Liver enzyme elevation
Your doctor may monitor liver function tests if you receive this medicine for a prolonged period.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Tricyclic antidepressants Major
Beta-blockers Moderate
Other vasodilators Moderate
Diuretics Minor

🚨 Major Interactions

  • MAO inhibitors
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Beta-blockers
  • Other vasodilators

🍷 Alcohol Interaction

Alcohol may enhance the dizziness and lightheadedness caused by this medicine. It is advisable to avoid alcohol while receiving this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Recent myocardial infarction","Severe hypotension","Active bleeding","Hypersensitivity to isoxsuprine","Severe cardiac arrhythmias"]

⚠️ Warnings & Precautions

["Use with caution in patients with cardiovascular disease.","May cause dizziness; avoid driving or operating machinery until effects are known.","Not recommended for patients with hyperthyroidism or diabetes without careful monitoring.","Prolonged use should be monitored with liver function tests.","Do not use if the solution is discolored or contains particulate matter."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe hypotension, tachycardia, and cardiac arrhythmias. Treatment is supportive and symptomatic. Seek immediate medical attention.

⏰ Missed Dose

This medicine is usually given by a healthcare professional in a clinical setting. If you miss a scheduled dose, contact your doctor or nurse as soon as possible. Do not attempt to self-administer a double dose.

Additional Safety Advice

General Safety

This medicine must be administered only by a healthcare professional. Do not attempt to self-inject. Inform your doctor if you have a history of heart disease, low blood pressure, thyroid problems, or diabetes. Avoid alcohol while receiving this medicine as it may worsen dizziness. Use caution when driving or operating machinery until you know how this medicine affects you. If you are pregnant or breastfeeding, consult your doctor before receiving this medicine. Do not use this medicine if the solution is discolored or contains particles. Keep all follow-up appointments and report any new or worsening symptoms immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the hypotensive and cardiac effects of this medicine. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before receiving this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be used after surgery to improve blood flow, but caution is needed if there is a risk of bleeding. Consult your surgeon.

🦷 Dental Procedures

Inform your dentist if you are receiving this medicine, as it may affect blood pressure and heart rate during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on blood vessels.
🥗
Engage in regular low-impact exercise like walking or swimming.
😴
Avoid smoking as it narrows blood vessels.
💧
Manage stress through relaxation techniques.
🧘
Follow a balanced diet rich in fruits and vegetables.

🏋️ Exercise Considerations

Avoid strenuous exercise immediately after receiving this medicine, as it may worsen dizziness or hypotension. Gradually resume activity as tolerated.

🥗 Diet Recommendations

Include omega-3 rich foods like fish.
Reduce salt intake to manage blood pressure.
Stay well hydrated.
Limit caffeine as it may increase heart rate.

💼 Impact on Daily Work & Life

This medicine may cause dizziness and fast heartbeat, which can affect your ability to drive or operate machinery. It is usually given in a clinical setting, so work impact is minimal if administered by a professional.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects, seek immediate medical attention. Your doctor will decide if and when to discontinue treatment.

📅 Long-Term Use Effects

Long-term use of this medicine may require monitoring of liver function and cardiovascular status. Prolonged use should be reviewed periodically by a doctor to assess continued benefit and potential risks.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Regular exercise, smoking cessation, and healthy diet can improve peripheral vascular disease.

Evidence: Well-established
Other vasodilators

Alternative medications like cilostazol may be used for peripheral vascular disease.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Consult your doctor for routine vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not freeze

✅ DO

Protect from light

❌ DON'T

Do not use if solution is discolored or contains particles

✅ DO

Keep out of reach of children

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

This medicine is administered by a healthcare professional, so travel is not typically applicable. If you are prescribed this medicine during travel, carry it in its original packaging with a copy of your prescription. Store at room temperature and protect from light. Check customs regulations for injectable medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 60-year-old man with peripheral vascular disease
He received this medicine as an intramuscular injection for his cold, painful feet. After a few doses, he noticed improved warmth and reduced pain. He was monitored for blood pressure changes and tolerated the medicine well.
💡 Lesson: Regular monitoring during treatment helps ensure safety and effectiveness.
👤 A 28-year-old pregnant woman with preterm labor
She was given this medicine intravenously to delay premature labor. Her contractions reduced, but she experienced palpitations. The doctor adjusted the dose and monitored her closely.
💡 Lesson: Close monitoring is essential when using this medicine in pregnancy, and side effects should be reported promptly.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within minutes after intravenous injection and within 10-30 minutes after intramuscular injection.

Q: Can I drive after receiving this medicine?

A: This medicine may cause dizziness. Avoid driving or operating machinery until you know how it affects you.

Q: Is this medicine safe during pregnancy?

A: It should be used during pregnancy only if clearly needed and prescribed by a doctor. Discuss the risks and benefits with your healthcare provider.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine at home?
  • How often can I receive this injection?
  • What are the risks during pregnancy?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while on this medicine?

🔄 Substitutes for adilan injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be self-injected at home.
    Fact: This medicine must be administered by a healthcare professional only.
  • Myth: This medicine is safe for everyone.
    Fact: It is contraindicated in certain heart conditions and should be used with caution in others.

📊 Comparison with Similar Medicines

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